Revisiting the interconnection between lipids and vitamin K metabolism: insights from recent research and potential therapeutic implications: a review

Table 1 Interventional studies of vitamin K on lipids profile

Intervention	Subjects	Dosage	Duration	Lipid	Findings	Ref
Phylloquinone, MK-4	Rat	600 mg/kg/d	3 months	TG	Phylloquinone: ↓TG by 48% MK-4: ↓TG by 29%	[33]
MK-7	Human	90 µg/d	8 weeks	TG	↓TG (p = 0.003)	[35]
Phylloquinone	Human	10 mg/d	8 weeks	TG, LDL-C,HDL-C, TC	No significant changes in lipid profile	[40]
Vitamin K2	Human	52 µg/d	12 weeks	TG,LDL-C,HDL-C,TC	No significant changes in lipid profile	[41]

ISSN: 1743-7075