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Fig. 6 | Nutrition & Metabolism

Fig. 6

From: Spexin ameliorated obesity-related metabolic disorders through promoting white adipose browning mediated by JAK2-STAT3 pathway

Fig. 6

SPX increases beige-fat specific markers in 3T3-L1 white adipocytes. (A ~ D) SPX increases the expressions of UCP1, TBX1 and CIDEA in 3T3-L1 adipocytes in a time-dependent and concentration-dependent manner. (E) The mRNA expression levels of UCP1, TBX1 and CIDEA in 100 nM SPX-treated differentiated 3T3-L1 adipocytes after 3 h. (F) Immunofluorescence staining shows increased expression of UCP1 upon 100 nM SPX treatment 3 h (×600 magnification; scale bar = 50 μm). All values are represented as means with error bars representing S.D. *, P < 0.05; **, P < 0.01. n = 6 for each group

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Nutrition & Metabolism

ISSN: 1743-7075

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