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Fig. 1 | Nutrition & Metabolism

Fig. 1

From: Exploration of vitamin D metabolic activity-related biological effects and corresponding therapeutic targets in prostate cancer

Fig. 1

Exploration of gene modules related to vitamin D metabolic activity. A: The cluster tree of 1045 patients with prostate cancer enrolled in the study, colored based on clustering. B: The expression heatmap of vitamin D synthesis related genes in all tissue samples, colored based on relative expression levels. C: Violin plot of the relative expression of vitamin D receptors in all tissue samples. The expression levels of different groups were compared by group T test. D: The Kaplan-Meier curves of disease-free survival of patients in different vitamin D activity groups, and log-rank test was to compare the difference in prognosis between the two groups. E: Results of gene module merging based on clustering and dynamic pruning methods. Each vertical line indicates a gene and each branch represents an expression module of highly interconnected genes. Below the dendrogram, different modules are given different colors. Gray indicates that genes are outside all modules. F: Analysis of network topology for the soft-threshold power. G: The correlations of gene modules with multiple clinical features, colored by P values and correlation coefficients

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