Table 3 Association between APOA5 genetic variants and metabolic syndrome risk

rs2266788

 A/A

1051/171

1.0 (ref)

1.0 (ref)

 A/G

546/114

1.28 (0.99–1.66)

0.06

1.37 (1.02–1.83)

0.038

 G/G

81/17

1.29 (0.75–2.23)

0.36

1.37 (0.75–2.51)

0.30

Dominant

 A/A

1051/171

1.0 (ref)

1.0 (ref)

 A/G + G/G

627/131

1.28 (1.00-1.65)

0.048

1.37 (1.03–1.81)

0.029

Recessive

 A/A + A/G

1597/285

1.0 (ref)

1.0 (ref)

 G/G

81/17

1.18 (0.69–2.01)

0.55

1.23 (0.68–2.21)

0.50

rs662799

 A/A

877/123

1.0 (ref)

1.0 (ref)

 A/G

663/136

1.46 (1.12–1.90)

0.005

1.57 (1.16–2.12)

0.003

 G/G

140/42

2.14 (1.44–3.17)

< 0.001

2.59 (1.66–4.04)

< 0.001

Dominant

 A/A

877/123

1.0 (ref)

1.0 (ref)

 A/G + G/G

803/178

1.58 (1.23–2.03)

< 0.001

1.74 (1.31–2.31)

< 0.001

Recessive

 A/A + A/G

1540/259

1.0 (ref)

1.0 (ref)

 G/G

140/42

1.78 (1.23–2.58)

0.002

2.09 (1.37–3.17)

< 0.001

rs651821

 T/T

863/121

1.0 (ref)

1.0 (ref)

 T/C

665/137

1.47 (1.13–1.91)

0.004

1.58 (1.17–2.13)

0.003

 C/C

139/42

2.16 (1.45–3.20)

< 0.001

2.64 (1.69–4.13)

< 0.001

Dominant

 T/T

863/121

1.0 (ref)

1.0 (ref)

 T/C + C/C

804/179

1.59 (1.24–2.04)

< 0.001

1.76 (1.32–2.33)

< 0.001

Recessive

 T/T + T/C

1528/258

1.0 (ref)

1.0 (ref)

 C/C

139/42

1.79 (1.24–2.59)

0.002

2.12 (1.39–3.22)

< 0.001