Adherence to the Eatwell Guide and cardiometabolic, cognitive and neuroimaging parameters: an analysis from the PREVENT dementia study

Table 3 Table of generalised additive models for associations between EWG and EWG graded with cardiometabolic risk scores, 4MT score and self-reported healthy eating

Dietary score	Unadjusted				Fully adjusted
Dietary score	β	SE	95% CI	p	β	SE	95% CI	p
Four Mountains Test
EWG	0.04	0.11	-0.18, 0.26	0.72	0.05	0.11	-0.18, 0.28	0.68
EWG graded	0.02	0.03	-0.04, 0.08	0.52	0.02	0.03	-0.04, 0.08	0.58
White Matter Lesion Volume
EWG	-0.005	0.01	-0.03, 0.02	0.64	-0.005	0.01	-0.02, 0.01	0.63
EWG graded	-0.001	0.003	-0.007, 0.004	0.66	-0.002	0.003	-0.007, 0.003	0.47
Left Hippocampus
EWG	-17.05	8.50	-34.04, -0.05	0.05	-14.85	8.74	-32.33, 2.63	0.09
EWG graded	-5.11	2.27	-9.66, -0.57	0.02	-4.28	2.38	-9.04, 0.48	0.07
Right Hippocampus
EWG	-15.43	9.50	-34.44, 3.57	0.11	-13.99	9.77	-33.52, 5.55	0.15
EWG graded	-1.47	2.55	-6.57, 3.63	0.57	-0.74	2.67	-6.07, 4.60	0.78
Left Hippocampal Thickness
EWG	0.001	0.002	-0.003, 0.005	0.51	0.002	0.002	-0.002, 0.006	0.40
EWG graded	0.0006	0.0005	-0.0004, 0.002	0.24	0.0008	0.0005	-0.0003, 0.002	0.13
Right Hippocampal Thickness
EWG	0.0006	0.002	-0.003, 0.004	0.73	0.001	0.002	-0.003, 0.005	0.54
EWG graded	0.0003	0.0005	-0.0006, 0.001	0.49	0.0006	0.0005	-0.0004, 0.002	0.26
Self-reported healthy eating
EWG	0.43	0.09	0.26, 0.60	< 0.001^¶	0.38	0.09	0.21, 0.57	< 0.001^¶
EWG graded	0.11	0.02	0.07, 0.16	< 0.001^¶	0.10	0.02	0.05, 0.14	< 0.001^¶

CI Confidence interval, 4MT Four Mountains Test, EWG Eatwell Guide score, FRS Framingham Risk Score. 4MT score fully adjusted model includes age, sex, education, APOEε4, parental history of dementia, NART score, physical activity score and socioeconomic status as covariates. Self-reported healthy eating score includes age, sex, education, APOEε4, parental history of dementia, APOEε4, physical activity score and socioeconomic status as covariates.
^¶p<0.05 after False Discovery Rate (FDR) adjustment.

ISSN: 1743-7075