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Table 3 Concentrations of free carnitine, acetyl carnitine and total carnitine in plasma, liver and muscle of rats fed diets without (Control) or with supplemented carnitine (Carnitine)

From: Supplementation of carnitine leads to an activation of the IGF-1/PI3K/Akt signalling pathway and down regulates the E3 ligase MuRF1 in skeletal muscle of rats

  Control Carnitine
Plasma (μmol/l)
Free carnitine 36 ± 5 91 ± 7*
Acetyl carnitine 16 ± 3 42 ± 6*
Total carnitine 52 ± 7 133 ± 10*
Liver (nmol/g dry matter)
Free carnitine 595 ± 70 1142 ± 158*
Acetyl carnitine 23 ± 13 74 ± 25*
Total carnitine 618 ± 72 1216 ± 142*
Muscle (nmol/g dry matter)
Free carnitine 2153 ± 321 3465 ± 420*
Acetyl carnitine 1246 ± 198 2571 ± 266*
Total carnitine 3399 ± 452 6036 ± 450*
  1. Values are means ± SD (n = 12/group). * indicates a significant difference to the control group (P < 0.05).