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Table 3 Concentrations of free carnitine, acetyl carnitine and total carnitine in plasma, liver and muscle of rats fed diets without (Control) or with supplemented carnitine (Carnitine)

From: Supplementation of carnitine leads to an activation of the IGF-1/PI3K/Akt signalling pathway and down regulates the E3 ligase MuRF1 in skeletal muscle of rats

 

Control

Carnitine

Plasma (μmol/l)

Free carnitine

36 ± 5

91 ± 7*

Acetyl carnitine

16 ± 3

42 ± 6*

Total carnitine

52 ± 7

133 ± 10*

Liver (nmol/g dry matter)

Free carnitine

595 ± 70

1142 ± 158*

Acetyl carnitine

23 ± 13

74 ± 25*

Total carnitine

618 ± 72

1216 ± 142*

Muscle (nmol/g dry matter)

Free carnitine

2153 ± 321

3465 ± 420*

Acetyl carnitine

1246 ± 198

2571 ± 266*

Total carnitine

3399 ± 452

6036 ± 450*

  1. Values are means ± SD (n = 12/group). * indicates a significant difference to the control group (P < 0.05).