Figure 6

The KD alters overall gene expression to more closely resemble that seen in normal brain. Eight microarrays were analyzed by 2-way ANOVA for interaction effects, using standard Bonferonni multiple testing correction. There were strong interactions between ketogenic diet and normal diet in non-tumor classes, especially in context of standard diet non-tumor. The trend is that many expression profiles in tumor mice on a ketogenic diet seem to trend back to a profile seen with mice living on a standard diet having no tumor.