Fig. 4

GABA modulates Pdx-1 a Mafa b and Gabra2 c mRNA expression. Results are the mean of at least three separate experiments. Values are means (n = 4), with standard errors represented by vertical bars. Means with different lower-case letters are significantly different (P < 0.05). Control, control medium; H₂O₂, medium containing 100 μM H₂O₂; H₂O₂ + (50 μM, 100 μM, 200 μM) GABA, medium containing 100 μM H₂O₂ and GABA