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Table 2 Insulin secretion from RINm5F cells in response to glucose (5.5 and 22 mmol/L) concentration*

From: Protective effects of γ-aminobutyric acid against H2O2-induced oxidative stress in RIN-m5F pancreatic cells

  Glucose
5.5 mmol/L 22 mmol/L
Control 25.45 ± 2.01 58.98 ± 7.27d
H2O2 20.14 ± 2.50 19.46 ± 3.17a
H2O2 + 50 μmol/L GABA 26.62 ± 1.65 22.32 ± 4.41a
H2O2 + 100 μmol/L GABA 24.71 ± 2.94 31.88 ± 4.30b
H2O2 + 200 μmol/L GABA 25.92 ± 3.16 38.70 ± 3.97c
  1. Control, control medium; H2O2, medium containing 100 μmol/L H2O2; H2O2 + (50 μmol/L, 100 μmol/L, 200 μmol/L) GABA, medium containing 100 μmol/L H2O2 and GABA
  2. *Values are expressed as mean ± SD (n = 8) of three separate experiments. Means with different superscript letters within a same column gare significantly different (P < 0.05)