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  1. Content type: Research

    The marine n-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) exert numerous beneficial effects on health, but their potency to improve treatment of type 2 diabetic (T2D) patients remains...

    Authors: Jiri Veleba, Jan Kopecky Jr., Petra Janovska, Ondrej Kuda, Olga Horakova, Hana Malinska, Ludmila Kazdova, Olena Oliyarnyk, Vojtech Skop, Jaroslava Trnovska, Milan Hajek, Antonin Skoch, Pavel Flachs, Kristina Bardova, Martin Rossmeisl, Josune Olza…

    Citation: Nutrition & Metabolism 2015 12:52

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  2. Content type: Review

    The number of obese patients has increased annually worldwide. Therefore, there is a strong need to develop a new effective and safe anti-obesity drug. Miglitol is an alpha-glucosidase inhibitor (αGI) that is ...

    Authors: Satoru Sugimoto, Hisakazu Nakajima, Kitaro Kosaka and Hajime Hosoi

    Citation: Nutrition & Metabolism 2015 12:51

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  3. Content type: Research

    Visceral fat area (VFA), a novel sex-specific index for visceral fat obesity (VFO) might play a major role in the development of vitamin D deficiency. However, the association between VFA and vitamin D insuffi...

    Authors: Meilin Zhang, Ping Li, Yufeng Zhu, Hong Chang, Xuan Wang, Weiqiao Liu, Yuwen Zhang and Guowei Huang

    Citation: Nutrition & Metabolism 2015 12:50

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  4. Content type: Review

    Cellular metabolic changes during chronic kidney disease (CKD) may induce higher production of oxygen radicals that play a significant role in the progression of renal damage and in the onset of important como...

    Authors: Simona Granata, Alessandra Dalla Gassa, Paola Tomei, Antonio Lupo and Gianluigi Zaza

    Citation: Nutrition & Metabolism 2015 12:49

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  5. Content type: Research

    From a health promotion perspective, the use of dietary indices is preferred above single nutrients and foods to evaluate diet quality. Longitudinal research about the association between dietary indices and r...

    Authors: Evelien Mertens, Benedicte Deforche, Patrick Mullie, Johan Lefevre, Ruben Charlier, Sara Knaeps, Inge Huybrechts and Peter Clarys

    Citation: Nutrition & Metabolism 2015 12:47

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  6. Content type: Methodology

    The most common methods for obtaining human resting metabolic rate (RMR) use either a ventilated hood connected to a metabolic cart (VH_MC) or calculation by many prediction equations utilizing the person’s he...

    Authors: Russell Rising, Kathryn Whyte, Jeanine Albu and Xavier Pi-Sunyer

    Citation: Nutrition & Metabolism 2015 12:46

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  7. Content type: Research

    Although the R230C-ATP-binding cassette A1 (ABCA1) variant has been consistently associated with HDL-C levels, its association with diabetes and other metabolic parameters is unclear. Estrogen and dietary factors...

    Authors: Leonor Jacobo-Albavera, Carlos Posadas-Romero, Gilberto Vargas-Alarcón, Sandra Romero-Hidalgo, Rosalinda Posadas-Sánchez, María del Carmen González-Salazar, Alessandra Carnevale, Samuel Canizales-Quinteros, Aida Medina-Urrutia, Erika Antúnez-Argüelles and Teresa Villarreal-Molina

    Citation: Nutrition & Metabolism 2015 12:45

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  8. Content type: Research

    Non-alcoholic fatty liver disease (NAFLD), characterized as excessive lipid accumulation within hepatocytes, is growing in prevalence. The exploitation of effective drugs for NAFLD has been proven challenging....

    Authors: Wencong Dai, Kunyuan Wang, Xinchun Zheng, Xiaohui Chen, Wenqing Zhang, Yiyue Zhang, Jinlin Hou and Li Liu

    Citation: Nutrition & Metabolism 2015 12:42

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  9. Content type: Research

    Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in developed countries. NAFLD encompasses a spectrum of diseases, ranging from hepatic steatosis to non-alcoholic ste...

    Authors: Rafat A. Siddiqui, Zhidong Xu, Kevin A. Harvey, Thomas M. Pavlina, Michael J. Becker and Gary P. Zaloga

    Citation: Nutrition & Metabolism 2015 12:41

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  10. Content type: Research

    Overweight in Guadeloupe is a public health matter affecting children and adults. In the present study we evaluated the metabolic profile, including serum ghrelin, leptin and adiponectin levels, in normal weig...

    Authors: Christine Rambhojan, Elodie Bouaziz-Amar, Laurent Larifla, Jacqueline Deloumeaux, Josiane Clepier, Jean Plumasseau, Jean-Marc Lacorte and Lydia Foucan

    Citation: Nutrition & Metabolism 2015 12:43

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  11. Content type: Research

    Maternal obesity is associated with dysregulation of glucose and lipid metabolism with consequent exposure of the fetus to an abnormal metabolic milieu. It is recognized that maternal obesity predisposes offsp...

    Authors: Sarah J. Glastras, Muh Geot Wong, Hui Chen, Jie Zhang, Amgad Zaky, Carol A. Pollock and Sonia Saad

    Citation: Nutrition & Metabolism 2015 12:40

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  12. Content type: Research

    It is well established that weight is an important determinant of bone health. Whereas obesity is associated with increased mortality and morbidity from diabetes and cardiovascular diseases, high body weight i...

    Authors: A. El Maghraoui, S. Sadni, A. El Maataoui, A. Majjad, A. Rezqi, Z. Ouzzif and A. Mounach

    Citation: Nutrition & Metabolism 2015 12:44

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  13. Content type: Research

    A short-term high-fat diet impairs mitochondrial function and the ability of skeletal muscle to respond to growth stimuli, but it is unknown whether such a diet alters the ability to respond to atrophy signals...

    Authors: Steven L. Roseno, Patrick R. Davis, Lance M. Bollinger, Jonathan J. S. Powell, Carol A. Witczak and Jeffrey J. Brault

    Citation: Nutrition & Metabolism 2015 12:39

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  14. Content type: Research

    Fat infiltration of the liver, muscle and pancreas is associated with insulin resistance and risk of diabetes. Weight loss reduces ectopic fat deposition and risk of diabetes, but is difficult to sustain to du...

    Authors: Nicola D. Guess, Anne Dornhorst, Nick Oliver, Jimmy D. Bell, E. Louise Thomas and Gary S. Frost

    Citation: Nutrition & Metabolism 2015 12:36

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  15. Content type: Research

    Energy restriction causes adaptations in energy expenditure (total-,TEE; resting-,REE; activity induced-,AEE).

    Authors: Stefan G. J. A. Camps, Sanne P. M. Verhoef, Nadia Roumans, Freek G. Bouwman, Edwin C. M. Mariman and Klaas R. Westerterp

    Citation: Nutrition & Metabolism 2015 12:37

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  16. Content type: Research

    Site-1 protease (S1P) is the key enzyme required for activation of the sterol regulatory element binding proteins (SREBPs) that govern lipid synthesis. While S1P has been speculated to influence plasma apoB-co...

    Authors: Debapriya Basu, Afroza Huq, Jahangir Iqbal, M. Mahmood Hussain, Xian-Cheng Jiang and Weijun Jin

    Citation: Nutrition & Metabolism 2015 12:35

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  17. Content type: Research

    Severe calorie restriction (CR) is shown to improve or even reverse β-cell dysfunction in patients with obesity and type 2 diabetes mellitus. However, whether mild to moderate CR can reverse β-cell dysfunction...

    Authors: Xiuying Gao, Dien Yan, Yinan Zhao, Hong Tao and Yingsheng Zhou

    Citation: Nutrition & Metabolism 2015 12:34

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  18. Content type: Research

    Obesity-induced hepatic lipid accumulation causes lipotoxicity, mitochondrial dysfunction, oxidative stress, and insulin resistance, and is implicated in non-alcoholic hepatic pathologies such as steatohepatit...

    Authors: Chu-Sook Kim, Yoonhee Kwon, Suck-Young Choe, Sun-Myung Hong, Hoon Yoo, Tsuyoshi Goto, Teruo Kawada, Hye-Seon Choi, Yeonsoo Joe, Hun Taeg Chung and Rina Yu

    Citation: Nutrition & Metabolism 2015 12:33

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  19. Content type: Research

    Recent studies have shown that vitamin-D intake can improve skeletal muscle function and strength in frail vitamin-D insufficient individuals. We investigated whether vitamin-D intake can improve the muscular ...

    Authors: Jakob Agergaard, Jeanette Trøstrup, Jacob Uth, Jonas Vestergard Iversen, Anders Boesen, Jesper L. Andersen, Peter Schjerling and Henning Langberg

    Citation: Nutrition & Metabolism 2015 12:32

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  20. Content type: Research

    Obesity is significant problem involving eating behavior and peripheral metabolic conditions. The effect of carbohydrate and fat restriction on appetite regulation, fibroblast growth factor 21 (FGF21) and lept...

    Authors: Lorena del Rocío Ibarra-Reynoso, Liudmila Pisarchyk, Elva Leticia Pérez-Luque, Ma. Eugenia Garay-Sevilla and Juan Manuel Malacara

    Citation: Nutrition & Metabolism 2015 12:31

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  21. Content type: Research

    Individuals with insulin resistance and resulting impaired glucose tolerance along with type 2 diabetes showed an increased prevalence of atherosclerosis. Our aim in this study was to address whether diet-indu...

    Authors: Bo Ning, Xiaoyan Wang, Ying Yu, Ahmed Bilal Waqar, Qi Yu, Tomonari Koike, Masashi Shiomi, Enqi Liu, Yifei Wang and Jianglin Fan

    Citation: Nutrition & Metabolism 2015 12:30

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  22. Content type: Research

    Both aging and obesity are related to dysregulated immune function, which may be responsible for increased risk of infection and also chronic non-infectious diseases. Dietary lipids have been shown to impact i...

    Authors: Mitra Rozati, Junaidah Barnett, Dayong Wu, Garry Handelman, Edward Saltzman, Thomas Wilson, Lijun Li, Junpeng Wang, Ascensión Marcos, José M. Ordovás, Yu-Chi Lee, Mohsen Meydani and Simin Nikbin Meydani

    Citation: Nutrition & Metabolism 2015 12:28

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  23. Content type: Research

    Non-alcoholic fatty liver disease (NAFLD) is rapidly turning into the most common liver disorder worldwide. One of the strategies that has been shown to effectively improve NAFLD is regular exercise, which see...

    Authors: Sheril Alex, Andreas Boss, Arend Heerschap and Sander Kersten

    Citation: Nutrition & Metabolism 2015 12:29

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