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Nutrition & Metabolism


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  1. Content type: Research

    Both aging and obesity are related to dysregulated immune function, which may be responsible for increased risk of infection and also chronic non-infectious diseases. Dietary lipids have been shown to impact i...

    Authors: Mitra Rozati, Junaidah Barnett, Dayong Wu, Garry Handelman, Edward Saltzman, Thomas Wilson, Lijun Li, Junpeng Wang, Ascensión Marcos, José M. Ordovás, Yu-Chi Lee, Mohsen Meydani and Simin Nikbin Meydani

    Citation: Nutrition & Metabolism 2015 12:28

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  2. Content type: Research

    Diacylglyceride acyltransferase 1 (DGAT1) is the enzyme that adds the final fatty acid on to a diacylglyceride during triglyceride (TG) synthesis. DGAT1 plays a key role in the repackaging of dietary TG into c...

    Authors: Rodney A. Velliquette, Kerry Grann, Stephen R. Missler, Jennifer Patterson, Chun Hu, Kevin W. Gellenbeck, Jeffrey D. Scholten and R. Keith Randolph

    Citation: Nutrition & Metabolism 2015 12:27

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  3. Content type: Review

    Zinc is a mineral that plays a vital role in many biological processes and plays an important role in insulin action and carbohydrate metabolism. It may also have a protective role in the prevention of atherog...

    Authors: Priyanga Ranasinghe, WS Wathurapatha, MH Ishara, R. Jayawardana, P. Galappatthy, P. Katulanda and GR Constantine

    Citation: Nutrition & Metabolism 2015 12:26

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  4. Content type: Perspective

    Intakes of high sugar-sweetened beverages (SSBs) in adults can escalate risk of metabolic syndrome (MetS); however, data of longitudinal studies in children and adolescents are lacking. In this study we assess...

    Authors: Parvin Mirmiran, Emad Yuzbashian, Golaleh Asghari, Somayeh Hosseinpour-Niazi and Fereidoun Azizi

    Citation: Nutrition & Metabolism 2015 12:25

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  5. Content type: Research

    Body mass index (BMI) and serum 25-hydroxy vitamin D3 (25OHD) concentrations are inversely related. As BMI contains only limited information regarding body fat distribution, we aimed to analyze the cross-secti...

    Authors: A. Hannemann, B. Heinsbaek Thuesen, N. Friedrich, H. Völzke, A. Steveling, T. Ittermann, K. Hegenscheid, M. Nauck, A. Linneberg and H. Wallaschofski

    Citation: Nutrition & Metabolism 2015 12:24

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  6. Content type: Research

    Ammonia detoxification is essential for physiological well-being, and the urea cycle in liver plays a predominant role in ammonia disposal. Nobiletin (NOB), a natural dietary flavonoid, is known to exhibit var...

    Authors: Kazunari Nohara, Youngmin Shin, Noheon Park, Kwon Jeong, Baokun He, Nobuya Koike, Seung-Hee Yoo and Zheng Chen

    Citation: Nutrition & Metabolism 2015 12:23

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  7. Content type: Research

    Cytokines secreted by adipose tissue macrophages (ATMs) significantly alter adipocyte function, inducing inflammatory responses and decreasing insulin sensitivity. However, little relevant information is avail...

    Authors: Yaqin Zhang, Li Shi, Hongliang Mei, Jiexin Zhang, Yunxia Zhu, Xiao Han and Dalong Zhu

    Citation: Nutrition & Metabolism 2015 12:21

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  8. Content type: Research

    A large body of evidence suggests that atherosclerosis is an inflammatory disease, in which cytokines and growth factors play a major role in disease progression. The methanolic extracts of Sphaeranthus indicus a...

    Authors: Rai Ajit K. Srivastava, Sapna Mistry and Somesh Sharma

    Citation: Nutrition & Metabolism 2015 12:20

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  9. Content type: Research

    Abdominal obesity is a major risk factor for insulin resistance, type 2 diabetes and cardiovascular diseases. Dietary fat induces insulin resistance in humans and rodents. The current study investigates whethe...

    Authors: Hilda E Ghadieh, Zachary N Smiley, Melissa W Kopfman, Mona G Najjar, Michael J Hake and Sonia M Najjar

    Citation: Nutrition & Metabolism 2015 12:19

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  10. Content type: Research

    South Asians were reported to have a higher liver fat content as compared to BMI-matched Caucasians. This study compared the increase in liver fat content in response to overfeeding with a high fat diet in Sou...

    Authors: Siti N. Wulan, Vera B. Schrauwen-Hinderling, Klaas R. Westerterp and Guy Plasqui

    Citation: Nutrition & Metabolism 2015 12:18

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  11. Content type: Research

    Diet-induced hepatic steatosis is highly associated with nonalcoholic fatty liver disease, which is related to the development of metabolic syndrome. While advanced stage nonalcoholic hepatic steatosis and ste...

    Authors: Yasuhito Shimada, Shisei Kuninaga, Michiko Ariyoshi, Beibei Zhang, Yasuhiko Shiina, Yoshinori Takahashi, Noriko Umemoto, Yuhei Nishimura, Hiroyuki Enari and Toshio Tanaka

    Citation: Nutrition & Metabolism 2015 12:17

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  12. Content type: Review

    The ability of inorganic nitrate and nitrite to convert to nitric oxide (NO), and some of its properties e.g. regulation of glucose metabolism, vascular homeostasis, and insulin signaling pathway, have recentl...

    Authors: Zahra Bahadoran, Asghar Ghasemi, Parvin Mirmiran, Fereidoun Azizi and Farzad Hadaegh

    Citation: Nutrition & Metabolism 2015 12:16

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  13. Content type: Brief communication

    Cigarette smoking is associated with an increased risk of type 2 diabetes mellitus (T2DM). Smokers exhibit low circulating levels of total adiponectin (ADPN) and high-molecular-weight (HMW) ADPN multimers. Blo...

    Authors: Mingzhen Li, Chunjun Li, Yu Liu, Yan Chen, Xiangdong Wu, Demin Yu, Victoria P Werth, Kevin Jon Williams and Ming-Lin Liu

    Citation: Nutrition & Metabolism 2015 12:15

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  14. Content type: Research

    There is great interest in the relationship between polyunsaturated fatty acids and health. Yet, the combinatory effect of factors such as sex, ethnicity, genetic polymorphisms and hormonal contraceptives (HC)...

    Authors: Salma A Abdelmagid, Shannon E Clarke, Kaitlin Roke, Daiva E Nielsen, Alaa Badawi, Ahmed El-Sohemy, David M Mutch and David WL Ma

    Citation: Nutrition & Metabolism 2015 12:14

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  15. Content type: Research

    Riboflavin (RF) is essential for normal cellular metabolic activities. Human cells obtain RF from their surroundings via a carrier-mediated process that involves RF transporters -1, -2 & -3 (hRFVT -1, -2 & -3;...

    Authors: Veedamali S Subramanian, Rubina Kapadia, Abhisek Ghosal and Hamid M Said

    Citation: Nutrition & Metabolism 2015 12:13

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  16. Content type: Methodology

    Metabolic therapy using ketogenic diets (KD) is emerging as an alternative or complementary approach to the current standard of care for brain cancer management. This therapeutic strategy targets the aerobic f...

    Authors: Joshua J Meidenbauer, Purna Mukherjee and Thomas N Seyfried

    Citation: Nutrition & Metabolism 2015 12:12

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  17. Content type: Research

    Pharmacological stimulation of peroxisome proliferator-activated receptor-gamma (PPAR-γ) has been recognized as a molecular switch in alleviating myocardial injury through modulating oxidative, inflammatory an...

    Authors: Neha Rani, Saurabh Bharti, Jagriti Bhatia, Ameesha Tomar, T C Nag, Ruma Ray and Dharamvir Singh Arya

    Citation: Nutrition & Metabolism 2015 12:11

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  18. Content type: Research

    The hallmark of Type 2 diabetes (T2D) is hyperglycemia, although there are multiple other metabolic abnormalities that occur with T2D, including insulin resistance and dyslipidemia. To advance T2D prevention a...

    Authors: Amit Kumar, Joseph Shiloach, Michael J Betenbaugh and Emily J Gallagher

    Citation: Nutrition & Metabolism 2015 12:8

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  19. Content type: Research

    Dementia induced by β-amyloid accumulation impairs peripheral glucose homeostasis, but red pepper extract improves glucose homeostasis. We therefore evaluated whether long-term oral consumption of different re...

    Authors: Hye Jeong Yang, Dae Young Kwon, Min Jung Kim, Suna Kang, Na Rang Moon, James W Daily and Sunmin Park

    Citation: Nutrition & Metabolism 2015 12:9

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  20. Content type: Research

    Diet has a significant relationship with the risk of coronary heart disease (CHD). Traditionally the effect of diet on CHD was measured with the biomarker for low-density lipoprotein (LDL) cholesterol. However...

    Authors: Marc J Mathews, Leon Liebenberg and Edward H Mathews

    Citation: Nutrition & Metabolism 2015 12:6

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  21. Content type: Research

    n-3 long chain polyunsaturated fatty acid (n-3 LC PUFA) increases β-oxidation and limits lipid accumulation in adipocytes. The current study was conducted to determine whether their precursor alpha-linolenic a...

    Authors: Xihong Zhou, Weiche Wu, Jingqing Chen, Xinxia Wang and Yizhen Wang

    Citation: Nutrition & Metabolism 2015 12:10

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  22. Content type: Brief communication

    Apolipoprotein (apo)B is the structural apoprotein of intestinally- and liver- derived lipoproteins and plays an important role in the transport of triacylglycerol (TAG) and cholesterol. Previous studies have ...

    Authors: Karani Santhanakrishnan Vimaleswaran, Anne M Minihane, Yue Li, Rosalyn Gill, Julie A Lovegrove, Christine M Williams and Kim G Jackson

    Citation: Nutrition & Metabolism 2015 12:7

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  23. Content type: Research

    Accumulative evidence in the literature suggests alcohol consumption is a protective factor of the metabolic syndrome (MS). However, few studies investigated the relationship between alcohol consumption and co...

    Authors: Jing Xiao, Jian-Ping Huang, Guang-Fei Xu, De-Xi Chen, Gui-Yun Wu, Min Zhang, Yi Shen and Hui Cai

    Citation: Nutrition & Metabolism 2015 12:5

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