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  1. Differences in total body and regional adiposity according to sex are observed from an early age, but these differences become more evident after puberty due to hormonal changes. We aimed to assess the evoluti...

    Authors: Silvana Paiva Orlandi, Leonardo Pozza Santos, Ana Maria Baptista Menezes, Fernando C. Wehrmeister, Helen Gonçalves and Maria Cecília Formoso Assunção
    Citation: Nutrition & Metabolism 2019 16:21
  2. Maternal undernutrition programs fetal energy homeostasis and increases the risk of metabolic disorders later in life. This study aimed to identify the signs of hepatic metabolic programming in utero and durin...

    Authors: Xiaoling Zhou, Hong Yang, Qiongxian Yan, Ao Ren, Zhiwei Kong, Shaoxun Tang, Xuefeng Han, Zhiliang Tan and Abdelfattah Z. M. Salem
    Citation: Nutrition & Metabolism 2019 16:20
  3. Maternal riboflavin deficiency (RD) induces embryonic death in poultry. The underlying mechanisms, however, remain to be established and an overview of molecular alterations at the protein level is still lacki...

    Authors: Jing Tang, Jian Hu, Ming Xue, Zhanbao Guo, Ming Xie, Bo Zhang, Zhengkui Zhou, Wei Huang and Shuisheng Hou
    Citation: Nutrition & Metabolism 2019 16:19
  4. Gut derived toxins such as p-cresol, p-cresyl sulfate (pCS) and indoxyl sulfate (IS), which belong to protein-bound uremic toxins that promote development of fibrosis inflammatory state associated with chronic...

    Authors: Hamid Tayebi Khosroshahi, Behzad Abedi, Morteza Ghojazadeh, Azam Samadi and Abolghasem Jouyban
    Citation: Nutrition & Metabolism 2019 16:18
  5. To investigate the influences of exercise on the levels of chemerin and its receptor chemokine-like receptor (CMKLR1) in the peripheral metabolic organs of obesity and diabetes rats, and whether the mechanism ...

    Authors: Xiaojing Lin, Yanan Yang, Jing Qu and Xiaohui Wang
    Citation: Nutrition & Metabolism 2019 16:17
  6. Epidemiological and experimental studies have extensively indicated that chronic subclinical systemic inflammation (CSSI) and oxidative stress are risk factors for several chronic diseases, including cancer, a...

    Authors: Yazan Ranneh, Abdah Md Akim, Hasiah Ab Hamid, Huzwah Khazaai, Abdulmannan Fadel and Ayman M. Mahmoud
    Citation: Nutrition & Metabolism 2019 16:15
  7. Adiponectin exerts several beneficial cardiovascular effects, however their specific molecular mechanisms require additional understanding. This study investigated the mechanisms of adiponectin action in the h...

    Authors: Amy Botta, Ying Liu, Sivaporn Wannaiampikul, Rungsunn Tungtrongchitr, Keith Dadson, Tae-Sik Park and Gary Sweeney
    Citation: Nutrition & Metabolism 2019 16:14
  8. Iron is a critical component of metabolic homeostasis, but consumption of dietary iron has increased dramatically in the last 30 years, corresponding with the rise of metabolic disease. While the link between ...

    Authors: Mario A. Miranda, Celine L. St Pierre, Juan F. Macias-Velasco, Huyen Anh Nguyen, Heather Schmidt, Lucian T. Agnello, Jessica P. Wayhart and Heather A. Lawson
    Citation: Nutrition & Metabolism 2019 16:13
  9. Oil tea is a type of traditional tea beverage used for treating various ailments in minority population in Guangxi, China. Our previous study showed oil tea improved glucose and lipid levels in type 2 diabetic...

    Authors: Qiantu Hu, Huafeng Chen, Yanli Zuo, Qin He, Xuan He, Steve Simpson Jr, Wei Huang, Hui Yang, Haiying Zhang and Rui Lin
    Citation: Nutrition & Metabolism 2019 16:12
  10. Catch-up growth in adult (CUGA) is characterized by visceral fat accumulation, ectopic lipid deposition and insulin resistance (IR). Here, we investigated the determinants of these pathophysiological consequen...

    Authors: Yan Li, Shan Yu, Lulu Chen, Xiang Hu, Juan Zheng and Xiuling Deng
    Citation: Nutrition & Metabolism 2019 16:11
  11. Oxidative stress-induced damage in endothelial cells is a crucial initiator of atherosclerosis (AS), which is highly related to excessive reactive oxygen species (ROS) and mitochondrial dynamics. Resveratrol (...

    Authors: Jining Yang, Xi Zhou, Xianglong Zeng, Ou Hu, Long Yi and Mantian Mi
    Citation: Nutrition & Metabolism 2019 16:9
  12. Since lifestyle changes are main therapies for non-alcoholic fatty liver disease (NAFLD), changing dietary components (nutritional or bioactive) may play a parallel important role. Few studies have assessed th...

    Authors: Seyed Ali Jazayeri-Tehrani, Seyed Mahdi Rezayat, Siavash Mansouri, Mostafa Qorbani, Seyed Moayed Alavian, Milad Daneshi-Maskooni and Mohammad-Javad Hosseinzadeh-Attar
    Citation: Nutrition & Metabolism 2019 16:8
  13. Small dense LDL cholesterol (sdLDL-c) has been established to be highly associated with metabolic disorder. However, the relationship between circulating sdLDL-c and the presence of metabolic syndrome (MetS) h...

    Authors: Jiahua Fan, Yangqing Liu, Songping Yin, Nixuan Chen, Xinxiu Bai, Qiuyi Ke, Jia Shen and Min Xia
    Citation: Nutrition & Metabolism 2019 16:7
  14. Obesity has become a public health concern worldwide because it is linked to numerous metabolic disorders, such as hyperlipidemia, hypertension and cardiovascular disease. Therefore, there is an urgent need to...

    Authors: Licong Yang, Yan Zhao, Yongfang Pan, Dongming Li and Guodong Zheng
    Citation: Nutrition & Metabolism 2019 16:6
  15. The GC haplotype of the vitamin D binding protein (encoded by the GC gene) might be a risk factor to the vitamin D (VD) nutritional status for many populations, while evidences from the Chinese Han population are...

    Authors: Ji-Chang Zhou, Yumei Zhu, Chunmei Gong, Xiongshun Liang, Xiaoying Zhou, Yuanfei Xu, Deliang Lyu, Junluan Mo, Jian Xu, Jinping Song, Xiaoling Che, Shiqiang Sun, Changhua Huang and Xiao-Li Liu
    Citation: Nutrition & Metabolism 2019 16:5
  16. Osteoporosis is one of the world’s major medical burdens in the twenty-first century. Pharmaceutical intervention currently focusses on decelerating bone loss, but phytochemicals such as baicalein, which is a ...

    Authors: Dominik Saul, Marie Weber, Marc Hendrik Zimmermann, Robyn Laura Kosinsky, Daniel Bernd Hoffmann, Björn Menger, Stefan Taudien, Wolfgang Lehmann, Marina Komrakova and Stephan Sehmisch
    Citation: Nutrition & Metabolism 2019 16:4
  17. Although retinol binding protein 4 (RBP4) has been implicated in insulin resistance in experimental studies, the association between RBP4 and risk of type 2 diabetes remains unclear. We assessed this associati...

    Authors: Yeli Wang, Liang Sun, Xu Lin, Jian-Min Yuan, Woon-Puay Koh and An Pan
    Citation: Nutrition & Metabolism 2019 16:3
  18. Effective evaluation or prediction of therapy response could be helpful for treatment of chronic kidney disease (CKD), which may rely on accurate biomarkers. Acylcarnitines are involved with lipid metabolism a...

    Authors: Fang-Ying Xia, Li Zhu, Chao Xu, Qing-Qing Wu, Wan-Jia Chen, Rong Zeng and Yue-Yi Deng
    Citation: Nutrition & Metabolism 2019 16:2
  19. Increased consumption of linoleic acid (LA, omega-6) in Western diets coupled with the pro-inflammatory and adipogenic properties of its derivatives has led to suggestions that fetal exposure to this dietary p...

    Authors: Sally A. V. Draycott, Ge Liu, Zoe C. Daniel, Matthew J. Elmes, Beverly S. Muhlhausler and Simon C. Langley-Evans
    Citation: Nutrition & Metabolism 2019 16:1
  20. Higher dietary intake of fibers and coffee, but lower red meat intake is associated with reduced risk for type 2 diabetes in epidemiological studies. We hypothesized that a calorie-restricted diet, which is hi...

    Authors: Yanislava Karusheva, Lejla Kunstein, Alessandra Bierwagen, Bettina Nowotny, Stefan Kabisch, Jan B. Groener, Ann Kristin Fleitmann, Christian Herder, Giovanni Pacini, Klaus Strassburger, Hans-Ulrich Häring, Peter P. Nawroth, Andreas F. H. Pfeiffer, Volker Burkart, Karsten Müssig, Michael Roden…
    Citation: Nutrition & Metabolism 2018 15:90
  21. Several studies have identified a negative association between serum glycine (Gly) levels and metabolic syndrome (MetS). However, this association has not been fully established in the elderly.

    Authors: Xianghui Li, Liang Sun, Wenduo Zhang, Hongxia Li, Siming Wang, Hongna Mu, Qi Zhou, Ying Zhang, Yueming Tang, Yu Wang, Wenxiang Chen, Ruiyue Yang and Jun Dong
    Citation: Nutrition & Metabolism 2018 15:89
  22. Although dietary patterns have been linked to chronic diseases such as cardiovascular disease, sparse data are available for a relationship between dietary patterns and incident chronic kidney disease (CKD) in...

    Authors: Golaleh Asghari, Mehrnaz Momenan, Emad Yuzbashian, Parvin Mirmiran and Fereidoun Azizi
    Citation: Nutrition & Metabolism 2018 15:88
  23. In a previous study, we showed that consumption of diets enriched in saturated fatty acids causes changes in alternative splicing of pre-mRNAs encoding a number of proteins in rat skeletal muscle, including th...

    Authors: Adam J. Black, Rudolf J. Schilder and Scot R. Kimball
    Citation: Nutrition & Metabolism 2018 15:87
  24. Non-alcoholic fatty liver disease (NAFLD) is a chronic and progressive liver disease with an increased risk of morbidity and mortality. However, so far no specific pharmacotherapy has been approved. Gynostemma pe...

    Authors: Ning Jia, Xiaoyan Lin, Shizhan Ma, Shujian Ge, Shumin Mu, Chongbo Yang, Shulong Shi, Ling Gao, Jin Xu, Tao Bo and Jiajun Zhao
    Citation: Nutrition & Metabolism 2018 15:86
  25. The current systematic review and meta-analysis of randomized controlled trials (RCTs) was conducted to summarize the effect of vitamin D supplementation on endothelial activation among patients with metabolic...

    Authors: Reza Tabrizi, Maryam Akbari, Kamran B. Lankarani, Seyed Taghi Heydari, Fariba Kolahdooz and Zatollah Asemi
    Citation: Nutrition & Metabolism 2018 15:85
  26. It has been proved that coffee consumption was associated with a lower risk of type 2 diabetes mellitus. But the benefit effect of coffee on hyperglycemia in Chinese population was largely unknown. Besides, th...

    Authors: Fei Gao, Yinan Zhang, Sheng Ge, Huijuan Lu, Ruihua Chen, Pingyan Fang, Yixie Shen, Congrong Wang and Weiping Jia
    Citation: Nutrition & Metabolism 2018 15:84
  27. Salvia hispanica seeds have been commonly used by people that seek healthy habits through natural foods to reduce cholesterol and triacylglycerides levels, however, the evidences that support this assumption are ...

    Authors: Cristiane Freitas Rodrigues, Willian Salgueiro, Matheus Bianchini, Juliana Cristina Veit, Robson Luiz Puntel, Tatiana Emanuelli, Cristiane Casagrande Dernadin and Daiana Silva Ávila
    Citation: Nutrition & Metabolism 2018 15:83
  28. Consumption of fructose-rich diets has been implicated in the increasing global prevalence of metabolic syndrome (MetS). Interventions during periods of early ontogenic developmental plasticity can cause epige...

    Authors: Trevor T. Nyakudya, Emmanuel Mukwevho and Kennedy H. Erlwanger
    Citation: Nutrition & Metabolism 2018 15:82
  29. Evidence has suggested a potential link exists between trimethylamine-N-oxide (TMAO), a choline-derived metabolite produced by gut microbiota, and some cancers, but little is known for primary liver cancer (PLC).

    Authors: Zhao-Yan Liu, Xu-Ying Tan, Qi-Jiong Li, Gong-Cheng Liao, Ai-Ping Fang, Dao-Ming Zhang, Pei-Yan Chen, Xiao-Yan Wang, Yun Luo, Jing-An Long, Rong-Huan Zhong and Hui-Lian Zhu
    Citation: Nutrition & Metabolism 2018 15:81
  30. Fasting and especially intermittent fasting have been shown to be an effective intervention in many diseases, such as obesity and diabetes. The fasting-mimicking diet (FMD) has recently been found to ameliorat...

    Authors: Siying Wei, Ruomei Han, Jingyu Zhao, Shuo Wang, Meiqin Huang, Yining Wang and Yan Chen
    Citation: Nutrition & Metabolism 2018 15:80
  31. Sex hormone-binding globulin (SHBG), a glycoprotein synthesized by hepatocytes, has been linked to insulin resistance and hepatic lipid metabolism and is suggested to be associated with nonalcoholic fatty live...

    Authors: Jing Luo, Qian Chen, Tianran Shen, Xu Wang, Wanjun Fang, Xiaocai Wu, Zenan Yuan, Gengdong Chen, Wenhua Ling and Yuming Chen
    Citation: Nutrition & Metabolism 2018 15:79
  32. Visceral adipose tissue (VAT) area is a strong predictor of obesity-related cardiometabolic alterations, but its measurement is costly, time consuming and, in some cases, involves radiation exposure. Glutamate...

    Authors: Ina Maltais-Payette, Marie-Michèle Boulet, Cornelia Prehn, Jerzy Adamski and André Tchernof
    Citation: Nutrition & Metabolism 2018 15:78
  33. Previous studies in teleost have demonstrated the adaptive strategy to maintain hepatic lipid homeostasis within certain limit. The excess of fat-intake could induce abnormal lipid deposition in liver but not ...

    Authors: Jie Wang, Xu-Fang Liang, Shan He, Jiao Li, Kang Huang, Yan-Peng Zhang and Dong Huang
    Citation: Nutrition & Metabolism 2018 15:77
  34. Bariatric surgery is a widely adopted treatment for obesity and its secondary complications. In the past decade, microvesicles (MVs) and CD36 have increasingly been considered as possible biomarkers for obesit...

    Authors: Jaco Botha, Morten Hjuler Nielsen, Maja Høegh Christensen, Henrik Vestergaard and Aase Handberg
    Citation: Nutrition & Metabolism 2018 15:76
  35. An ability to switch between primarily oxidizing fat in the fasted state to carbohydrate in the fed state, termed metabolic flexibility, is associated with insulin sensitivity. Metabolic flexibility has been e...

    Authors: Nicholas T. Broskey, Charmaine S. Tam, Elizabeth F. Sutton, Abby D. Altazan, Jeffrey H. Burton, Eric Ravussin and Leanne M Redman
    Citation: Nutrition & Metabolism 2018 15:75
  36. Diabetes mellitus is one of the most common chronic diseases that accompanied by severe complications. Gynura divaricata (GD), a medicinal and edible plant that is usually used for the treatment of diabetes. Ther...

    Authors: Xiao-Lu Yin, Bing-Qing Xu and Yu-Qing Zhang
    Citation: Nutrition & Metabolism 2018 15:73
  37. Advanced glycation end products (AGEs), a group of compounds that are formed by non-enzymatic reactions between carbonyl groups of reducing sugars and free amino groups of proteins, lipids or nucleic acids, ca...

    Authors: Jie-Hua Chen, Xu Lin, Cuihong Bu and Xuguang Zhang
    Citation: Nutrition & Metabolism 2018 15:72
  38. Non-alcoholic fatty liver disease (NAFLD) covers a spectrum of lesions ranging from steatosis to a complex pattern, nonalcoholic steatohepatitis (NASH). Ultrasonography provides important information on hepati...

    Authors: Guozhen Cui, Robert C Martin, Xingkai Liu, Qianqian Zheng, Harshul Pandit, Ping Zhang, Wei Li and Yan Li
    Citation: Nutrition & Metabolism 2018 15:71
  39. This study aimed to assess the association between the angiopoietin-like protein 4 gene (ANGPTL4) single nucleotide polymorphisms (SNPs) and serum lipid levels, the risk of coronary artery disease (CAD) and ische...

    Authors: Qian Yang, Rui-Xing Yin, Xiao-Li Cao, Feng Huang, Yi-Jiang Zhou and Wu-Xian Chen
    Citation: Nutrition & Metabolism 2018 15:70
  40. Metabolic Syndrom has become a public health problem. It mainly results from the increased consumption of fat and sugar. In this context, the benefits of personalized moderate exercise training were investigat...

    Authors: Julie Dupas, Annie Feray, Anthony Guernec, Morgane Pengam, Manon Inizan, François Guerrero, Jacques Mansourati and Christelle Goanvec
    Citation: Nutrition & Metabolism 2018 15:69
  41. MicroRNAs (miRNAs), a class of single-stranded non-coding RNA of about 22 nucleotides, are potent regulators of gene expression existing in both plants and animals. Recent studies showed that plant miRNAs coul...

    Authors: Zhiqing Li, Ruodan Xu and Ning Li
    Citation: Nutrition & Metabolism 2018 15:68

    The Correction to this article has been published in Nutrition & Metabolism 2018 15:74

  42. Weight loss, especially fat mass reduction, helps to improve blood glucose control, insulin sensitivity, and β-cell function. This study aimed to compare the effect of exenatide and glargine on body compositio...

    Authors: Ting-Ting Yin, Yan Bi, Ping Li, Shan-Mei Shen, Wei-Min Wang, Can Jiang, Cai-Xia Gao, Yan Wang, Li-Jun Gao, Da-Long Zhu and Wen-Huan Feng
    Citation: Nutrition & Metabolism 2018 15:67
  43. Increased oxidative stress and impaired antioxidant defense are important mechanisms in the pathogenesis of diabetic myopathy. Alpha-lipoic acid (ALA) has been indicated as a weight-loss treatment in rodents a...

    Authors: Oak-Kee Hong, Jang-Won Son, Hyuk-Sang Kwon, Seong-Su Lee, Sung-Rae Kim and Soon Jib Yoo
    Citation: Nutrition & Metabolism 2018 15:66
  44. We previously reported on the anti-obesogenic and anti-inflammatory effects associated with n-3 long-chain polyunsaturated fatty acids (LCPUFA) in our diet-induced obesity (DIO) mouse model. Two isocaloric hig...

    Authors: Stefanie Worsch, Mathias Heikenwalder, Hans Hauner and Bernhard L. Bader
    Citation: Nutrition & Metabolism 2018 15:65
  45. Dietary interventions have been shown to attenuate some of the myocardial pathological alterations associated with obesity. This study evaluated the effect of dietary normalization from a fat/fructose/choleste...

    Authors: Laura Jul Andreasen, Simone Krog, Trine Pagh Ludvigsen, Ole Lerberg Nielsen, Jacob Eifer Møller, Berit Østergaard Christoffersen, Henrik Duelund Pedersen and Lisbeth Høier Olsen
    Citation: Nutrition & Metabolism 2018 15:64
  46. Non-alcoholic fatty liver disease (NAFLD) is the hepatic component of metabolic syndrome. Despite the beneficial health effects of cardamom on dyslipidemia, hepatomegaly, and fasting hyperglycemia, no previous...

    Authors: Milad Daneshi-Maskooni, Seyed Ali Keshavarz, Mostafa Qorbani, Siavash Mansouri, Seyed Moayed Alavian, Mahtab Badri-Fariman, Seyed Ali Jazayeri-Tehrani and Gity Sotoudeh
    Citation: Nutrition & Metabolism 2018 15:63
  47. Muscle protein synthesis and muscle net balance plateau after moderate protein ingestion in adults. However, it has been suggested that there is no practical limit to the anabolic response of whole-body net ba...

    Authors: Michael Mazzulla, Kimberly A. Volterman, Jeff E. Packer, Denise J. Wooding, Jahmal C. Brooks, Hiroyuki Kato and Daniel R. Moore
    Citation: Nutrition & Metabolism 2018 15:62

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