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  1. It was evidenced that saturated fatty acids (FAs) have a detrimental effect on pancreatic β-cells function and survival, leading to endoplasmic reticulum (ER) calcium release, ER stress, and apoptosis. In the ...

    Authors: Jan Šrámek, Vlasta Němcová and Jan Kovář
    Citation: Nutrition & Metabolism 2021 18:74
  2. Despite the worldwide burden of diverticular disease, the connections between diverticular disease and dietary habits remain poorly understood, particularly in an asymptomatic representative sample. We investi...

    Authors: Esther Askani, Susanne Rospleszcz, Theresa Rothenbacher, Nina Wawro, Helmut Messmann, Carlo N. De Cecco, Ricarda von Krüchten, Charlotte Kulka, Lena S. Kiefer, Wolfgang Rathmann, Annette Peters, Christopher L. Schlett, Fabian Bamberg, Jakob Linseisen and Corinna Storz
    Citation: Nutrition & Metabolism 2021 18:73
  3. Cardiac hypertrophy is an independent risk factor of many cardiovascular diseases. Studies have demonstrated that microRNA-126 (miR-126) was involved in angiogenesis during physiological and pathological proce...

    Authors: Haiyu Li, Xiaoxu Tian, Yongjuan Ruan, Junhui Xing and Zhe Meng
    Citation: Nutrition & Metabolism 2021 18:71
  4. Hypertension is a known risk factor for multiple chronic diseases. Existing literature on the association between frequency of spicy food consumption and hypertension shows mixed findings.

    Authors: Hao Wang, Lingli Chen, Dun Shen, Yuan Cao, Xiaoyi Zhang, Kaixu Xie, Chunmei Wang, Shuiqing Zhu, Pei Pei, Yu Guo, Fiona Bragg, Min Yu, Zhengming Chen and Liming Li
    Citation: Nutrition & Metabolism 2021 18:70
  5. The incidence of obesity is increasing worldwide, and it is a risk factor for diabetes, dyslipidemia, and nonalcoholic fatty liver disease. Our previous study had demonstrated that high-fat diet induced increa...

    Authors: Hongying Cai, Zhiguo Wen, Kun Meng and Peilong Yang
    Citation: Nutrition & Metabolism 2021 18:69
  6. Metabolic syndrome (MetS) is significantly associated with the risk of cardiovascular disease and its prevalence is showing a trend of getting younger. Previous studies on the relationship between elements and...

    Authors: Huidi Zhang, Qingqing Man, Pengkun Song, Siran Li, Xiaobing Liu, Lijuan Wang, Yuqian Li, Yichun Hu and Lichen Yang
    Citation: Nutrition & Metabolism 2021 18:67
  7. Dairy intake has been implicated in later ovarian aging but mechanism underlying the association is unknown. This study aimed to investigate (1) associations between dairy intake and metabolites previously sho...

    Authors: Nazanin Moslehi, Rezvan Marzbani, Hassan Rezadoost, Parvin Mirmiran, Fahimeh Ramezani Tehrani and Fereidoun Azizi
    Citation: Nutrition & Metabolism 2021 18:66
  8. Impaired hepatic fatty acid metabolism and persistent mitochondrial dysfunction are phenomena commonly associated with liver failure. Decreased serum levels of L-carnitine, a amino acid derivative involved in ...

    Authors: Pengtao Li, Zhengguo Xia, Weichang Kong, Qiong Wang, Ziyue Zhao, Ashley Arnold, Qinglian Xu and Jiegou Xu
    Citation: Nutrition & Metabolism 2021 18:65
  9. This study investigated the mechanisms underlying the preventive effect of dihydromyricetin (DHM) against liver fibrosis involving hepatic stellate cells (HSCs) and hepatic natural killer (NK) cells.

    Authors: Xi Zhou, Li Yu, Min Zhou, Pengfei Hou, Long Yi and Mantian Mi
    Citation: Nutrition & Metabolism 2021 18:64
  10. Previous reports regarding the predictive power of adiposity indices remain inconsistent, and longitudinal studies on this top are limited. The associations of hyperuricemia risk with changes in obesity status...

    Authors: Zonglei Zhou, Kunpeng Li, Xianzhi Li, Rongsheng Luan and Ruzhen Zhou
    Citation: Nutrition & Metabolism 2021 18:62
  11. Previous work in HEK-293 cells demonstrated the importance of amino acid-induced mTORC1 translocation to the lysosomal surface for stimulating mTORC1 kinase activity and protein synthesis. This study tested th...

    Authors: Michael S. Borack, Jared M. Dickinson, Christopher S. Fry, Paul T. Reidy, Melissa M. Markofski, Rachel R. Deer, Kristofer Jennings, Elena Volpi and Blake B. Rasmussen
    Citation: Nutrition & Metabolism 2021 18:61
  12. The practical relevance of metabolic adaptation remains a controversial issue. To the best of our knowledge, no study has properly evaluated the role of metabolic adaptation in modulating weight loss outcomes....

    Authors: Catia Martins, Jessica Roekenes, Barbara A. Gower and Gary R. Hunter
    Citation: Nutrition & Metabolism 2021 18:60
  13. To prospectively examine the associations of baseline serum uric acid (SUA) and SUA changes with incident metabolic syndrome (MetS) and update the evidence through a meta-analysis.

    Authors: Sen Chen, Nianwei Wu, Chuan Yu, Ying Xu, Chengfu Xu, Yuli Huang, Jian Zhao, Ningxiu Li and Xiong-Fei Pan
    Citation: Nutrition & Metabolism 2021 18:59
  14. Feeding rhythm disruption contributes to the development of obesity. The receptors of glucagon-like peptide-1 (GLP-1) are distributed in the wide regions of the brain. Among these regions, GLP-1 receptors (GLP...

    Authors: Yuko Maejima, Shoko Yokota, Masaru Shimizu, Shoichiro Horita, Daisuke Kobayashi, Akihiro Hazama and Kenju Shimomura
    Citation: Nutrition & Metabolism 2021 18:58
  15. Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders among women of reproductive age. This study was designed to investigate the effects of melatonin and/or magnesium supplementation ...

    Authors: Mohammad Alizadeh, Majid Karandish, Mohammad Asghari Jafarabadi, Lida Heidari, Roshan Nikbakht, Hossein Babaahmadi Rezaei and Reihaneh Mousavi
    Citation: Nutrition & Metabolism 2021 18:57
  16. High-fat diet (HFD)-induced obesity causes immune cells to infiltrate adipose tissue, leading to chronic inflammation and metabolic syndrome. Brown adipose tissue (BAT) can dissipate the energy produced by lip...

    Authors: Pengyu Fu, Rongxin Zhu, Jie Jia, Yang Hu, Chengjun Wu, Pawel Cieszczyk, Hans-Christer Holmberg and Lijing Gong
    Citation: Nutrition & Metabolism 2021 18:56
  17. The TM4 (UBAC2) protein, which contains 4 transmembrane domains and one ubiquitin binding domain, is mainly expressed in cell and nuclear membranes. The current research aimed to explore the role of TM4 in metabo...

    Authors: Lili Chen, Kuanping Ye, Xiaocheng Feng, Lianxi Li, Qin Li, Ying Huang, Xuanchun Wang, Rumei Li, Cheng Hu, Zhen Yang, Bin Lu, Yehong Yang, Jie Wen, Zhaoyun Zhang, Min He, Qinghua Wang…
    Citation: Nutrition & Metabolism 2021 18:54
  18. Soybean oil is a very common edible oil in daily life. With the changes in the dietary composition, the intake of soybean oil increased. However, the effects of dietary intake of soybean oil on testosterone pr...

    Authors: Yu Su, Zhenhua Tian, Xiangyu Qi, Dandan Luo, Luna Liu, Shuang Liu, Dongmei Zheng, Fang Wei, Zhao He and Qingbo Guan
    Citation: Nutrition & Metabolism 2021 18:53
  19. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Pariyarath Sangeetha Thondre, Helen Lightowler, Lis Ahlstrom and Andrew Gallagher
    Citation: Nutrition & Metabolism 2021 18:52

    The original article was published in Nutrition & Metabolism 2021 18:41

  20. Whether vitamin D supplementation has any effect on body fat percentage, especially among elite athletes, remains unclear. The aim of this study was to evaluate the effect of vitamin D supplementation on serum...

    Authors: Itaru Kawashima, Takashi Tsukahara, Ryosuke Kawai, Takafumi Mizuno, Shinya Ishizuka, Hideki Hiraiwa and Shiro Imagama
    Citation: Nutrition & Metabolism 2021 18:51
  21. Mitochondrial dysfunction has been implicated as a significant factor in the liver disease process. Blueberry juice and probiotics (BP) synergistically improve liver function in alcoholic fatty liver disease (...

    Authors: Houmin Fan, Yanyan Shen, Ya Ren, Qiuju Mou, Tao Lin, Lili Zhu and Tingting Ren
    Citation: Nutrition & Metabolism 2021 18:50
  22. Tight junction proteins play crucial roles in maintaining the intestinal mucosal barrier. Although previous studies have shown that Notch signaling is closely related to tight junction proteins, the mechanism ...

    Authors: Fubin Qiu, Zehui Zhang, Linxue Yang, Rui Li and Ying Ma
    Citation: Nutrition & Metabolism 2021 18:49
  23. Caloric restriction (CR) has become increasingly attractive in the treatment of type 2 diabetes mellitus (T2DM) because of the increasingly common high-calorie diet and sedentary lifestyle. This study aimed to...

    Authors: Li Zhang, Ying-juan Huang, Jia-pan Sun, Ting-ying Zhang, Tao-li Liu, Bin Ke, Xian-fang Shi, Hui Li, Geng-peng Zhang, Zhi-yu Ye, Jianguo Hu and Jian Qin
    Citation: Nutrition & Metabolism 2021 18:48
  24. Application of mixed meal tolerance tests (MMTT) to measure beta-cell function in long-term studies is limited by modification of the commercial products occurring over time. This study assessed the intra-indi...

    Authors: Theresa Kössler, Pavel Bobrov, Klaus Strassburger, Oliver Kuss, Oana-Patricia Zaharia, Yanislava Karusheva, Clara Möser, Kálmán Bódis, Volker Burkart, Michael Roden and Julia Szendroedi
    Citation: Nutrition & Metabolism 2021 18:47
  25. Withania coagulans (Stocks) Dunal fruits are used in the therapeutics of several ailments due to possessing of potent phytoconstituents which is also used traditionally for curing the diabetes.

    Authors: Heera Ram, Pramod Kumar, Ashok Purohit, Priya Kashyap, Suresh Kumar, Shivani Kumar, Garima Singh, Abdulaziz A. Alqarawi, Abeer Hashem, Elsayed Fathi Abd-Allah, Al-Bandari Fahad Al-Arjani and Bhim Pratap Singh
    Citation: Nutrition & Metabolism 2021 18:43
  26. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Amin Salehpour, Mehdi Hedayati, Farzad Shidfar, Asal Neshatbini Tehrani, Ali Asghar Farshad and Saeed Mohammadi
    Citation: Nutrition & Metabolism 2021 18:42

    The original article was published in Nutrition & Metabolism 2021 18:29

  27. There are many benefits of maintaining healthy blood glucose levels, and studies have shown that lifestyle changes such as changes to diet can successfully restore normoglycaemia in participants with dysglycae...

    Authors: Pariyarath Sangeetha Thondre, Helen Lightowler, Lis Ahlstrom and Andrew Gallagher
    Citation: Nutrition & Metabolism 2021 18:41

    The Correction to this article has been published in Nutrition & Metabolism 2021 18:52

  28. To meet the needs of foetal growth and development, marked changes in lipid profiles occur during pregnancy. Abnormal lipid metabolism is often accompanied by adverse pregnancy outcomes, which seriously affect...

    Authors: Jiayu Lu, Ying Gong, Xinhong Wei, Zhenyu Yao, Rui Yang, Jinxing Xin, Ling Gao and Shanshan Shao
    Citation: Nutrition & Metabolism 2021 18:40
  29. Mechanism exploitation of energy homeostasis is urgently required because of the worldwide prevailing of obesity-related metabolic disorders in human being. Although it is well known that leptin plays a centra...

    Authors: Huimin Liu, Tianxin Du, Chen Li and Guoqing Yang
    Citation: Nutrition & Metabolism 2021 18:39
  30. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Zhiliang Cai, Qiaoxuan Zhang, Ziqiang Xia, Songbai Zheng, Lilan Zeng, Liqiao Han, Jun Yan, Peifeng Ke, Junhua Zhuang, Xinzhong Wu and Xianzhang Huang
    Citation: Nutrition & Metabolism 2021 18:38

    The original article was published in Nutrition & Metabolism 2020 17:8

  31. Hypercholesterolemia is a major risk factor for cardiovascular disease. It has been reported that pineapple contains healthy nutrients and phytochemicals associated with antioxidant and anti-inflammatory capac...

    Authors: Porrnthanate Seenak, Sarawut Kumphune, Wachirawadee Malakul, Ratanon Chotima and Nitirut Nernpermpisooth
    Citation: Nutrition & Metabolism 2021 18:36
  32. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Wanzi Jiang, Shushu Huang, Shuai Ma, Yingyun Gong, Zhenzhen Fu, Li Zhou, Wen Hu, Guofang Mao, Zhimin Ma, Ling Yang, Guangfeng Tang, Xiaofang Sun, Ping Zhang, Jianling Bai, Lei Chen, Bimin Shi…
    Citation: Nutrition & Metabolism 2021 18:35

    The original article was published in Nutrition & Metabolism 2021 18:17

  33. Leucine deprivation modulates the dietary amino acid composition, reducing the fat content and improving the glucose tolerance, thus protecting the organism against obesity. However, a complete deprivation of ...

    Authors: Ziheng Zhou, Hanrui Yin, Yajie Guo, Yuanyuan Fang, Feixiang Yuan, Shanghai Chen and Feifan Guo
    Citation: Nutrition & Metabolism 2021 18:34
  34. Many chronic disease patients experience a concurrent loss of lean muscle mass. Skeletal muscle is a dynamic tissue maintained by continuous protein turnover and progenitor cell activity. Muscle stem cells, or...

    Authors: Josiane Joseph and Jason D. Doles
    Citation: Nutrition & Metabolism 2021 18:33
  35. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Golbarg Rahimi, Salime Heydari, Bahareh Rahimi, Navid Abedpoor, Iman Niktab, Zahra Safaeinejad, Maryam Peymani, Farzad Seyed Forootan, Zahra Derakhshan, Mohammad Hossein Nasr Esfahani and Kamran Ghaedi
    Citation: Nutrition & Metabolism 2021 18:32

    The original article was published in Nutrition & Metabolism 2021 18:14

  36. Due to the lack of evidence, advice pertaining to glycemic load (GL) can be misleading. Does the excessive restriction of GL, mostly through an extreme reduction in carbohydrate intake, result in a relatively ...

    Authors: Fengyi He, Chaogang Chen, Feng Li, Yiqin Qi, Xiuhong Lin, Ping Liang, Meng Ren and Li Yan
    Citation: Nutrition & Metabolism 2021 18:31
  37. Neck circumference, a proxy for upper-body subcutaneous fat, is a unique and pathogenic fat depot that confers additional metabolic risk. The purpose of present study was to determine whether neck circumferenc...

    Authors: Jie Shi, Zixuan Wang, Weiwei Zhang, Yixin Niu, Ning Lin, Xiaoyong Li, Hongmei Zhang, Guang Ning, Jiangao Fan, Li Qin, Qing Su and Zhen Yang
    Citation: Nutrition & Metabolism 2021 18:30
  38. 1,25-dihydroxyvitamin D3 may regulate adipogenesis in adipocytes in-vitro, but little is known about possible molecular mechanisms related to the inhibitory effect of 1,25-dihydroxyvitamin D3 on adipogenesis i...

    Authors: Amin Salehpour, Mehdi Hedayati, Farzad Shidfar, Asal Neshatbini Tehrani, Ali Asghar Farshad and Saeed Mohammadi
    Citation: Nutrition & Metabolism 2021 18:29

    The Correction to this article has been published in Nutrition & Metabolism 2021 18:42

  39. Cardiovascular diseases (CVDs) are associated with an unhealthy lifestyle, including poor diet. Indices reflecting the overall quality of diets are more effective than single food or nutrient-based approaches ...

    Authors: Fatemeh Nouri, Masoumeh Sadeghi, Noushin Mohammadifard, Hamidreza Roohafza, Awat Feizi and Nizal Sarrafzadegan
    Citation: Nutrition & Metabolism 2021 18:28
  40. Cancer-associated cachexia is a multifactorial syndrome defined by progressive weight loss with ongoing loss of adipose tissue and skeletal muscle. Adipose loss occurs in the early stage of cachexia and is ass...

    Authors: Jun Han, Lei Shen, Zheng Zhan, Yuguo Liu, Chang Zhang, Ruochen Guo, Yangjun Luo, Zhiqin Xie, Ying Feng and Guohao Wu
    Citation: Nutrition & Metabolism 2021 18:27
  41. Nonalcoholic fatty liver disease (NAFLD) is the most prevalent liver disease and is characterized by excessive fat accumulation. Kaili Sour Soup, a food typical of Guizhou Province, is believed to have signifi...

    Authors: Shuo Cong, Zhengchao Li, Lei Yu, Yongmei Liu, Yaxin Hu, Ying Bi and Mingliang Cheng
    Citation: Nutrition & Metabolism 2021 18:26
  42. The link between total cholesterol (TC) and all-cause and specific mortality has not been elucidated. Herein, we aimed to evaluate the effect of TC levels on all-cause, cardiovascular disease (CVD), and cancer...

    Authors: Guo-dong He, Xiao-cong Liu, Lin Liu, Yu-ling Yu, Chao-lei Chen, Jia-yi Huang, Kenneth Lo, Yu-qing Huang and Ying-qing Feng
    Citation: Nutrition & Metabolism 2021 18:25

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