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  1. Obesity, characterized by the excessive accumulation of triglycerides in adipocytes and their decreased excretion from adipocytes, is closely related to various health problems. Ginsenoside Rb1 (Rb1), the most...

    Authors: Rong Guo, Lei Wang, Xianqin Zeng, Minghao Liu, Peng Zhou, Huixia Lu, Huili Lin and Mei Dong
    Citation: Nutrition & Metabolism 2020 17:69
  2. Physical exercise and activity status may modify the effect of the fat mass- and obesity-associated (FTO) genotype on body weight and obesity risk. To understand the interaction between FTO’s effect and physical ...

    Authors: Jessica Danaher, Christos G. Stathis, Robin A. Wilson, Alba Moreno-Asso, R. Mark Wellard and Matthew B. Cooke
    Citation: Nutrition & Metabolism 2020 17:68
  3. Early nutritional programming affects a series of metabolism, growth and development in mammals. Fish also exhibit the developmental plasticity by early nutritional programming. However, little is known about ...

    Authors: Qiang-Sheng Zhu, Jie Wang, Shan He, Xu-Fang Liang, Shuang Xie and Qian-Qian Xiao
    Citation: Nutrition & Metabolism 2020 17:67
  4. Early diagnosis of type 2 diabetes mellitus (T2DM) is still difficult. Screening of plasma biomarkers has great significance of optimizing diagnosis and predicting the complications of T2DM.

    Authors: Shuai Wang, Zhiyuan Lu, Yuxin Wang, Tianran Zhang and Xiaodong He
    Citation: Nutrition & Metabolism 2020 17:66
  5. Propolis is a sticky, resinous material gather from plants and is blended with wax and other constituents. It is reported to have anti-inflammatory, anti-oxidative and blood glucose-lowering properties. This r...

    Authors: Naseh Pahlavani, Mahsa Malekahmadi, Safieh Firouzi, Daryoush Rostami, Alireza Sedaghat, Ahmad Bagheri Moghaddam, Gordon A. Ferns, Jamshid Gholizadeh Navashenaq, Reza Reazvani, Mohammad Safarian and Majid Ghayour-Mobarhan
    Citation: Nutrition & Metabolism 2020 17:65
  6. Insulin resistance and accumulation of visceral adipose tissue (VAT) and intermuscular adipose tissue (IMAT) place aging adults with obesity at high risk of cardio-metabolic disease. A very low carbohydrate di...

    Authors: Amy M Goss, Barbara Gower, Taraneh Soleymani, Mariah Stewart, May Pendergrass, Mark Lockhart, Olivia Krantz, Shima Dowla, Nikki Bush, Valene Garr Barry and Kevin R. Fontaine
    Citation: Nutrition & Metabolism 2020 17:64
  7. Hypertriglyceridemic waist (HTGW) phenotype has been suggested as a risk factor for chronic kidney disease (CKD). However, there is limited evidence on the relationship of triglyceride waist phenotypes with es...

    Authors: Yun Qiu, Qi Zhao, Na Wang, Yuting Yu, Ruiping Wang, Yue Zhang, Shuheng Cui, Meiying Zhu, Xing Liu, Yonggen Jiang and Genming Zhao
    Citation: Nutrition & Metabolism 2020 17:63
  8. The relationship between selenium (Se) and insulin resistance remains unclear. We aim to explore the association between toenail Se levels and insulin resistance through a cross-sectional study comprising Chin...

    Authors: Qiuyun Gu, Xueying Cui, Kun Du, Bian Wang, Wei Cai, Qingya Tang and Xiuhua Shen
    Citation: Nutrition & Metabolism 2020 17:62
  9. Dietary protein deficiency and amino acid imbalance cause hepatic fat accumulation. We previously demonstrated that only arginine deficiency or total amino acid deficiency in a diet caused significant hepatic ...

    Authors: Lila Otani, Hiroki Nishi, Ayaka Koyama, Yuta Akasaka, Yusuke Taguchi, Yuka Toyoshima, Daisuke Yamanaka, Fumihiko Hakuno, Huijuan Jia, Shin-Ichiro Takahashi and Hisanori Kato
    Citation: Nutrition & Metabolism 2020 17:60
  10. Previous studies indicated that serum 25-hydroxyvitamin D [25(OH)D] concentrations are positively associated with physical activity levels independent of sun exposure. However, the effect of resistance trainin...

    Authors: Xiaomin Sun, Xiao-Kai Ma, Lin Zhang and Zhen-Bo Cao
    Citation: Nutrition & Metabolism 2020 17:59
  11. Both low vitamin D status and metabolic syndrome (MetS) are worldwide concerns, and low 25-hydroxyvitamin D [25(OH)D] levels are associated with MetS; however, related epidemiological evidence based on elderly...

    Authors: Ling Liu, Zhaojin Cao, Feng Lu, Yingchun Liu, Yuebin Lv, Yingli Qu, Heng Gu, Chengcheng Li, Jiayi Cai, Saisai Ji, Yawei Li, Feng Zhao and Xiaoming Shi
    Citation: Nutrition & Metabolism 2020 17:58
  12. As a lipid metabolic disorder, non-alcoholic fatty liver disease (NAFLD) is an important cause of cirrhosis and hepatocellular carcinoma, with no effective drug up to date. Previous studies have demonstrated i...

    Authors: Jingjie Wang, Yitong Zhang, Qin Zhuo, Yujen Tseng, Jiucun Wang, Yanyun Ma, Jun Zhang and Jie Liu
    Citation: Nutrition & Metabolism 2020 17:46
  13. Although obesity is considered as the main cause of Type II diabetes (T2DM), non-obese individuals may still develop T2DM and obese individuals may not.

    Authors: Somayeh Alsadat Hosseini Khorami, Mohd Sokhini Abd Mutalib, Mohammad Feili Shiraz, Joseph Anthony Abdullah, Zulida Rejali, Razana Mohd Ali and Huzwah Khaza’ai
    Citation: Nutrition & Metabolism 2020 17:55
  14. The gut microbiota plays a critical role in obesity and lipid metabolism disorder. Chokeberry (Aronia melanocarpa L.) are rich in polyphenols with various physiological and pharmacological activities. We determin...

    Authors: Yue Zhu, Jia-ying Zhang, Yu-long Wei, Jing-yi Hao, Yu-qing Lei, Wan-bin Zhao, Yu-hang Xiao and Ai-dong Sun
    Citation: Nutrition & Metabolism 2020 17:54
  15. Lower post-prandial glucose (PPG) and insulin (PPI) responses to foods are associated with reduced diabetes risk and progression. Several plant extracts have been proposed to reduce PPG or PPI by inhibiting en...

    Authors: David J. Mela, Xiu-Zhen Cao, Rajendra Dobriyal, Mark I. Fowler, Li Lin, Manoj Joshi, Theo J. P. Mulder, Peter G. Murray, Harry P. F. Peters, Mario A. Vermeer and Zhang Zhang
    Citation: Nutrition & Metabolism 2020 17:51
  16. Metabolically healthy obesity (MHO) has been reported to be associated with the development of vascular damage by the carotid intima-media thickness, but the relationship between metabolic health and obesity p...

    Authors: Yue Yuan, Jian-Jun Mu, Chao Chu, Wen-Ling Zheng, Yang Wang, Jia-Wen Hu, Qiong Ma, Yu Yan, Yue-Yuan Liao and Chen Chen
    Citation: Nutrition & Metabolism 2020 17:50
  17. Obesity has reached an alarming rate worldwide. Promoting thermogenesis via increasing the function of brown adipose tissue (BAT) or white adipose tissue (WAT) browning has been proposed as a new protective ap...

    Authors: Naimeh Mesri Alamdari, Pardis Irandoost, Neda Roshanravan, Mohammadreza Vafa, Mohammad Asghari Jafarabadi, Shahriar Alipour, Leila Roshangar, Mohammadreza Alivand, Farnaz Farsi and Farzad Shidfar
    Citation: Nutrition & Metabolism 2020 17:42
  18. Obesity is becoming one of the most severe global health problems. However, risk of developing normal weight obesity, where an individual has a high percentage of body fat despite a normal body mass index, is ...

    Authors: Yuko Maejima, Shoko Yokota, Shoichiro Horita and Kenju Shimomura
    Citation: Nutrition & Metabolism 2020 17:48
  19. Detox diet are known as a popular dieting strategies that helps toxins elimination and weight manage but there is very little clinical evidence. The Wellnessup diet (WD) used in the present study designed as a...

    Authors: Su-Jin Jung, Woo-Lim Kim, Byung-Hyun Park, Seung-Ok Lee and Soo-Wan Chae
    Citation: Nutrition & Metabolism 2020 17:47
  20. Hepatic insulin resistance (IR) is an early pathological characteristic of many metabolic diseases, such as type 2 diabetes. Long noncoding RNAs (lncRNAs) have been identified as mediators of IR and related di...

    Authors: Zengyuan Zhou, Xue Zhao, Liang Chen, Yuzheng Li, Zhao Chen, Yuanyuan Wang, Zihao Zhou and Xia Chu
    Citation: Nutrition & Metabolism 2020 17:45
  21. Vitamin D deficiency has been often observed in obese persons. One of the mechanisms suggested for low vitamin D status in obesity was decreased bioavailability of vitamin D (VD) due to sequestration in adipos...

    Authors: Chan Yoon Park, Yongho Shin, Jeong-Han Kim, Shuang Zhu, Young Sun Jung and Sung Nim Han
    Citation: Nutrition & Metabolism 2020 17:44
  22. Parenteral nutrition (PN)-associated liver disease (PNALD) is a common and life-threatening complication in patients receiving PN. However, its definitive etiology is not yet clear. Therefore, performed proteo...

    Authors: Gulisudumu Maitiabola, Feng Tian, Haifeng Sun, Li Zhang, Xuejin Gao, Bin Xue and Xinying Wang
    Citation: Nutrition & Metabolism 2020 17:43
  23. Atherosclerosis (AS), which characterized with the accumulation of lipids on the vessel wall, is the pathological basis of many cardiovascular diseases (CVD) and seriously threatens human health. Resveratrol (...

    Authors: Liyu Zhou, Jun Long, Yuting Sun, Weikai Chen, Runze Qiu and Dongping Yuan
    Citation: Nutrition & Metabolism 2020 17:41
  24. Even Non-alcoholic steatohepatitis (NASH) has been becoming the key role in process of liver fibrosis or cirrhosis, no any NASH involving liver fibrosis mice model which consistent with the mechanisms of fatty...

    Authors: Xin Xin, Bei-Yu Cai, Cheng Chen, Hua-Jie Tian, Xin Wang, Yi-Yang Hu and Qin Feng
    Citation: Nutrition & Metabolism 2020 17:40
  25. Accumulating evidence shows that circulating levels of trimethylamine N-oxide, which is generated from the metabolism of dietary choline, may predict cardiovascular disease among Caucasians. Acute coronary syn...

    Authors: Yuxiang Dai, Qianqian Tian, Jing Si, Zhonghan Sun, Shalaimaiti Shali, Lili Xu, Daoyuan Ren, Shufu Chang, Xin Dong, Hongxia Zhao, Zhendong Mei, Yan Zheng and Junbo Ge
    Citation: Nutrition & Metabolism 2020 17:39
  26. The aims of this study were to verify the effect of progressive-chronic and acute sodium bicarbonate (SB) supplementation on the anaerobic capacity, blood acid-base balance, and discipline-specific performance...

    Authors: Krzysztof Durkalec-Michalski, Paulina M. Nowaczyk, Jacek Adrian, Joanna Kamińska and Tomasz Podgórski
    Citation: Nutrition & Metabolism 2020 17:38
  27. High fat diet impact transcription of hepatic genes responsible for drug metabolism and pharmacokinetics. Until now, researches just focused on a couple specific genes without a global profile showing. Age-dep...

    Authors: Yuqi He, Tao Yang, Yimei Du, Lin Qin, Feifei Ma, Zunping Wu, Hua Ling, Li Yang, Zhengtao Wang, Qingdi Zhou, Guangbo Ge and Yanliu Lu
    Citation: Nutrition & Metabolism 2020 17:37
  28. Obesity is associated with chronic inflammation, which contributes to cardiovascular diseases. MicroRNAs (miRNAs) are reported to be involved in vascular inflammation and atherosclerosis. Abelmoschus esculentus (...

    Authors: Luoning Gou, Geng Liu, Rong Ma, Anita Regmi, Tianshu Zeng, Juan Zheng, Xueyu Zhong and Lulu Chen
    Citation: Nutrition & Metabolism 2020 17:35
  29. Gypenosides (Gyp) are the main ingredient of the Chinese medicine, Gynostemma pentaphyllum. They are widely used in Asia as a hepatoprotective agent. Here, we elucidated the mechanism of Gyp in non-alcoholic stea...

    Authors: Hongshan Li, Yingfei Xi, Xin Xin, Huajie Tian and Yiyang Hu
    Citation: Nutrition & Metabolism 2020 17:34
  30. Knowledge of the physiologic requirement for iron, the core index for the formulation of a dietary reference intake (DRI), is of great importance for the health of a pregnant woman and her fetus, and can help ...

    Authors: Jie Cai, Tongxiang Ren, Jiaxi Lu, Jinghuan Wu, Deqian Mao, Weidong Li, Yu Zhang, Min Li, Jianhua Piao, Lichen Yang, Yuxia Ma, Jun Wang and Xiaoguang Yang
    Citation: Nutrition & Metabolism 2020 17:33
  31. Infant anemia is prevalent in low- and middle-income countries. Maternal body mass index (BMI) is associated with serum ferritin in cord blood, but as yet has not been linked to infant anemia. The objective of...

    Authors: Shaohua Yin, Yubo Zhou, Hongtian Li, Zhihao Cheng, Yali Zhang, Le Zhang, Jufen Liu and Jianmeng Liu
    Citation: Nutrition & Metabolism 2020 17:32
  32. Pomegranate juice (POMj) contains abundant soluble polyphenolic antioxidant compounds and is recommended for its cardioprotective/atheroprotective properties. However, very few studies have investigated the ef...

    Authors: Achraf Ammar, Khaled Trabelsi, Stephen J. Bailey, Mouna Turki, Nicola Luigi Bragazzi, Omar Boukhris, Kais El Abed, Mohamed Bouaziz, Fatma Ayadi, Tarak Driss, Nizar Souissi, Hamdi Chtourou and Anita Hökelmann
    Citation: Nutrition & Metabolism 2020 17:31
  33. Resveratrol is a natural polyphenolic compound that ameliorates postmenopausal osteoporosis by activating the estrogen receptor. Research has shown that resveratrol exhibits some type of estrogen receptor agon...

    Authors: Wei Wang, Li-Mei Zhang, Chang Guo and Jian-Feng Han
    Citation: Nutrition & Metabolism 2020 17:29
  34. This study aimed to identify a dietary pattern (DP) characterised mainly by high intakes of free sugar and other nutrients hypothesised to be associated with obesity such as dietary energy density (DED), perce...

    Authors: Nor Aishah Emi, Wan Ying Gan, Zalilah Mohd Shariff, Azriyanti Anuar Zaini, Nurainul Hana Shamsuddin, Mahenderan Appukutty and Geeta Appannah
    Citation: Nutrition & Metabolism 2020 17:28
  35. Obesity is a severe public health threat worldwide. Emerging evidence suggests that gut microbiota dysbiosis is closely associated with obesity and its related metabolic complications. The aim of the present s...

    Authors: Wendong Wang, Mintao Zhong, Tiantian Yu, Lei Chen, Lijun Shi, Junwei Zong and Shouyu Wang
    Citation: Nutrition & Metabolism 2020 17:27
  36. Androgen receptor (AR) has been reported to play vital roles in exercise-induced increase of muscle mass in rats, but needs to be further verified and the mechanism behind remains unclear. As AR target genes, ...

    Authors: Lijun YIN, Lin LU, Xiaojing LIN and Xiaohui WANG
    Citation: Nutrition & Metabolism 2020 17:26
  37. Higher choline and betaine levels have been linked to lower risk of liver cancer, whereas existing data in relation to hepatocellular carcinoma (HCC) prognosis are scarce. Our objective was to examine the asso...

    Authors: Zhao-Yan Liu, Dinuerguli Yishake, Ai-Ping Fang, Dao-Ming Zhang, Gong-Cheng Liao, Xu-Ying Tan, Yao-Jun Zhang and Hui-Lian Zhu
    Citation: Nutrition & Metabolism 2020 17:25
  38. Evaluation of the action of various traditional plants to treat metabolic syndrome are strongly studied. In our study, we investigated the effect of the Tunisian jojoba seed on a metabolic syndrome induced in ...

    Authors: Sahla Belhadj, Stephanie Dal, Fakhreddine Khaskhoussi, Elisa Maillard-Pedracini, Olfa Hentati and Séverine Sigrist
    Citation: Nutrition & Metabolism 2020 17:24
  39. Metastatic cancer is incurable and understanding the molecular underpinnings is crucial to improving survival for our patients. The IGF-1/Akt signaling pathway is often impaired in cancer leading to its progre...

    Authors: Anuradha A. Shastri, Anthony Saleh, Jason E. Savage, Tiziana DeAngelis, Kevin Camphausen and Nicole L. Simone
    Citation: Nutrition & Metabolism 2020 17:23
  40. Trehalose is a functional disaccharide that has anti-metabolic activities such as suppression of adipocyte hypertrophy in mice and alleviation of impaired glucose tolerance in humans. Trehalase hydrolyzes treh...

    Authors: Chikako Arai, Aki Suyama, Shigeyuki Arai, Norie Arai, Chiyo Yoshizane, Satomi Koya-Miyata, Akiko Mizote, Shin Endo, Toshio Ariyasu, Hitoshi Mitsuzumi and Shimpei Ushio
    Citation: Nutrition & Metabolism 2020 17:22
  41. Obesity occurs when the body’s energy intake is constantly greater than its energy consumption and the pharmacological enhancing the activity of brown adipose tissue (BAT) and (or) browning of white adipose ti...

    Authors: Gang Wei, Honglin Sun, Jun-li Liu, Kai Dong, Junli Liu and Min Zhang
    Citation: Nutrition & Metabolism 2020 17:21
  42. Biosyntheses of proteins, nucleotides and fatty acids, are essential for the malignant proliferation and survival of cancer cells. Cumulating research findings show that amino acid restrictions are potential s...

    Authors: Jian-Sheng Kang
    Citation: Nutrition & Metabolism 2020 17:20

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