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  1. Amyotrophic lateral sclerosis (ALS) is a form of degenerative motor neuron disease. At the end stage of the disease artificial feeding is often required. Nevertheless, very little is known about the energy dem...

    Authors: Waltteri Siirala, Klaus T Olkkola, Tommi Noponen, Arno Vuori and Riku Aantaa
    Citation: Nutrition & Metabolism 2010 7:70
  2. We aimed to characterize the lasting effect of moderate caloric restriction during early pregnancy on offspring energy homeostasis, by focusing on the effects on food intake and body weight as well as on the i...

    Authors: Mariona Palou, Teresa Priego, Juana Sánchez, Andreu Palou and Catalina Picó
    Citation: Nutrition & Metabolism 2010 7:69
  3. A sedentary lifestyle and increased consumption of energy dense food have become more common in many parts of the world. The aim of this study was to study long term effects on body composition after a four we...

    Authors: Åsa Ernersson, Fredrik H Nystrom and Torbjörn Lindström
    Citation: Nutrition & Metabolism 2010 7:68
  4. Macrophage infiltration in adipose tissue together with the aberrant production of pro-inflammatory cytokines has been identified as the key link between obesity and its related metabolic disorders. This study...

    Authors: Ruby LC Hoo, Janice YL Wong, CF Qiao, A Xu, HX Xu and Karen SL Lam
    Citation: Nutrition & Metabolism 2010 7:67
  5. The cellular and molecular mechanisms of adipose tissue biology have been studied extensively over the last two decades. Adipose tissue growth involves both an increase in fat cell size and the formation of ma...

    Authors: Ralf Siegner, Stefan Heuser, Ursula Holtzmann, Jörn Söhle, Andreas Schepky, Thomas Raschke, Franz Stäb, Horst Wenck and Marc Winnefeld
    Citation: Nutrition & Metabolism 2010 7:66
  6. The thermogenic and metabolic properties of capsinoids appear to mimic those of the more pungent sister compound capsaicin. However, few data exist on how capsinoid ingestion affects energy expenditure in huma...

    Authors: Andrea R Josse, Scott S Sherriffs, Andrew M Holwerda, Richard Andrews, Aaron W Staples and Stuart M Phillips
    Citation: Nutrition & Metabolism 2010 7:65
  7. We previously determined that a weight-maintenance, non-ketogenic diet containing 30% carbohydrate (CHO), 30% protein, 40% fat, (30:30:40) (LoBAG30) decreased glycated hemoglobin (%tGHb) from 10.8 to 9.1% over a ...

    Authors: Mary C Gannon, Heidi Hoover and Frank Q Nuttall
    Citation: Nutrition & Metabolism 2010 7:64
  8. Little is known with respect to the metabolic response and the requirements of infected newborns. Moreover, the nutritional needs and particularly the energy metabolism of newborns with sepsis are controversia...

    Authors: Rubens Feferbaum, Cláudio Leone, Arnaldo AF Siqueira, Vitor E Valenti, Paulo R Gallo, Alberto OA Reis, Ary C Lopes, Viviane G Nascimento, Adriana G de Oliveira, Tatiana Dias de Carvalho, Rubens Wajnsztejn, Claudia de Castro Selestrin and Luiz Carlos de Abreu
    Citation: Nutrition & Metabolism 2010 7:63
  9. It is undetermined whether calcium supplementation has an effect on obesity or body composition in postmenopausal women. The purpose of the study is to detect the effect of calcium supplementation on indices o...

    Authors: Jiapeng Zhou, Lan-Juan Zhao, Patrice Watson, Qin Zhang and Joan M Lappe
    Citation: Nutrition & Metabolism 2010 7:62
  10. Calcium (Ca) - fortified foods are likely to play an important role in helping the consumer achieve an adequate Ca intake, especially for persons with a low intake of dairy products. Fish bones have a high Ca ...

    Authors: Marian K Malde, Susanne Bügel, Mette Kristensen, Ketil Malde, Ingvild E Graff and Jan I Pedersen
    Citation: Nutrition & Metabolism 2010 7:61
  11. Conjugated linoleic acid (cis-9, trans-11 CLA) and trans-11 vaccenic acid (VA) are found naturally in ruminant-derived foods. CLA has been shown to have numerous potential health related effects and has been exte...

    Authors: M Miriam Jacome-Sosa, Jing Lu, Ye Wang, Megan R Ruth, David C Wright, Martin J Reaney, Jianheng Shen, Catherine J Field, Donna F Vine and Spencer D Proctor
    Citation: Nutrition & Metabolism 2010 7:60
  12. Calorie restriction (CR) and endurance exercise are known to attenuate obesity and improve the metabolic syndrome. The aim of this study was to directly compare the effects of CR and endurance exercise in a mo...

    Authors: Ping Huang, Shoufeng Li, Mengle Shao, Qibin Qi, Feng Zhao, Jia You, Ting Mao, Wenjun Li, Zhen Yan and Yong Liu
    Citation: Nutrition & Metabolism 2010 7:59
  13. Old age is associated with an involuntary and progressive but physiological loss of muscle mass. The aim of this study was to evaluate the effects of exclusive consumption for 6 months of a protein-enriched en...

    Authors: Josune Olza, María D Mesa, Rafael M Poyatos, Concepción M Aguilera, Rosario Moreno-Torres, Milagros Pérez, Antonio Pérez de la Cruz and Angel Gil
    Citation: Nutrition & Metabolism 2010 7:58
  14. Leucine may function as a signaling molecule to regulate metabolism. We have previously shown that dietary leucine supplementation significantly improves glucose and energy metabolism in diet-induced obese mic...

    Authors: Kaiying Guo, Yi-Hao Yu, Jue Hou and Yiying Zhang
    Citation: Nutrition & Metabolism 2010 7:57
  15. The health benefits of polyunsaturated fatty acids (PUFAs), particularly those of the n-3 series are well documented. The mechanisms by which these effects are mediated are not fully clarified.

    Authors: Joanne F Doleman, John J Eady, Ruan M Elliott, Rob J Foxall, John Seers, Ian T Johnson and Elizabeth K Lund
    Citation: Nutrition & Metabolism 2010 7:56
  16. Antioxidant supplementations have the potential to alleviate the atherosclerotic damage caused by excessive production of reactive oxygen species (ROS). The present study evaluated the effects of prolonged ant...

    Authors: Marina Shargorodsky, Ortal Debby, Zipora Matas and Reuven Zimlichman
    Citation: Nutrition & Metabolism 2010 7:55
  17. Physical exercise beneficially impacts on the plasma lipoprotein profile as well as on the incidence of cardiovascular events and is therefore recommended in primary and secondary prevention strategies against...

    Authors: Maxi Meissner, Niels Nijstad, Folkert Kuipers and Uwe JF Tietge
    Citation: Nutrition & Metabolism 2010 7:54
  18. Dietary ratios of omega-3 (n-3) to omega-6 (n-6) polyunsaturated fatty acids (PUFAs) have been implicated in controlling markers of the metabolic syndrome, including insulin sensitivity, inflammation, lipid pr...

    Authors: Paul R Burghardt, Elyse S Kemmerer, Bradley J Buck, Andrew J Osetek, Charles Yan, Lauren G Koch, Steven L Britton and Simon J Evans
    Citation: Nutrition & Metabolism 2010 7:53
  19. Research on the uptake and transport of astaxanthin is lacking in most species. We studied the uptake of astaxanthin by plasma, lipoproteins and leukocytes in domestic dogs and cats.

    Authors: Jean Soon Park, Hong Wook Kim, Bridget D Mathison, Michael G Hayek, Stefan Massimino, Gregory A Reinhart and Boon P Chew
    Citation: Nutrition & Metabolism 2010 7:52
  20. Regardless of age or gender, resistance training or provision of adequate amounts of dietary protein (PRO) or essential amino acids (EAA) can increase muscle protein synthesis (MPS) in healthy adults. Combined...

    Authors: Juha J Hulmi, Christopher M Lockwood and Jeffrey R Stout
    Citation: Nutrition & Metabolism 2010 7:51
  21. N-acylethanolamines (NAEs), such as anandamide (AEA), are a group of endogenous lipids derived from a fatty acid linked to ethanolamine and have a wide range of biological activities, including regulation of me.....

    Authors: Michel M Joosten, Michiel GJ Balvers, Kitty CM Verhoeckx, Henk FJ Hendriks and Renger F Witkamp
    Citation: Nutrition & Metabolism 2010 7:49
  22. To determine the effects of high sucrose diets on vascular reactivity. We hypothesized that similar to high fat diets (HFD), HSD feeding would lead to increased adiposity resulting in inflammation and oxidativ...

    Authors: Karen L Sweazea, Mateja Lekic and Benjimen R Walker
    Citation: Nutrition & Metabolism 2010 7:48
  23. Appropriate long-term drinking of red wine is associated with a reduced risk of cardiovascular disease. Resveratrol, a well-known SIRT1 activator is considered to be one of the beneficial components contained ...

    Authors: Tomoko Tsukamoto, Rieko Nakata, Emi Tamura, Yukiko Kosuge, Aya Kariya, Michiko Katsukawa, Satoshi Mishima, Tetsuro Ito, Munekazu Iinuma, Yukihiro Akao, Yoshinori Nozawa, Yuji Arai, Shobu Namura and Hiroyasu Inoue
    Citation: Nutrition & Metabolism 2010 7:46
  24. The detrimental effects of maternal under-nutrition during gestation on fetal development are well known with an increased propensity of metabolic disorders identified in the adult offspring. Understanding exa...

    Authors: Hassendrini N Peiris, Anna P Ponnampalam, Murray D Mitchell and Mark P Green
    Citation: Nutrition & Metabolism 2010 7:44
  25. The lipid content of the chylomicrons is a key biomarker and risk factor of cardiovascular diseases and for the understanding of obesity. A high throughput determination of chylomicrons in human blood plasma i...

    Authors: Francesco Savorani, Mette Kristensen, Flemming H Larsen, Arne Astrup and Søren B Engelsen
    Citation: Nutrition & Metabolism 2010 7:43
  26. Fruits and vegetables are important sources of fiber and nutrients with a recognized antioxidant capacity, which could have beneficial effects on the proinflammatory status as well as some metabolic syndrome a...

    Authors: Helen Hermana M Hermsdorff, María Ángeles Zulet, Blanca Puchau and José Alfredo Martínez
    Citation: Nutrition & Metabolism 2010 7:42
  27. Subchronic administration of the potent pharmaceutical estrogen diethylstilbestrol (DES) to female Fischer 344 (F344) rats induces growth of large, hemorrhagic pituitaries that progress to tumors. Phytoestroge...

    Authors: Yow-Jiun Jeng, Mikhail Kochukov, Dhananjaya Nauduri, Bhupendra S Kaphalia and Cheryl S Watson
    Citation: Nutrition & Metabolism 2010 7:40
  28. The Forbes equation relating fat-free mass (FFM) to fat mass (FM) has been used to predict longitudinal changes in FFM during weight change but has important limitations when paired with a one dimensional energy ...

    Authors: Diana Thomas, Sai Krupa Das, James A Levine, Corby K Martin, Laurel Mayer, Andrew McDougall, Boyd J Strauss and Steven B Heymsfield
    Citation: Nutrition & Metabolism 2010 7:39
  29. Selenium is an essential micronutrient known for its antioxidant function. However, the association of serum selenium with lipid profiles and fasting glucose are inconsistent in populations with average intake...

    Authors: Kuen-Cheh Yang, Long-Teng Lee, Yow-Shan Lee, Hui-Ying Huang, Ching-Yu Chen and Kuo-Chin Huang
    Citation: Nutrition & Metabolism 2010 7:38
  30. Epidemiological studies associate consumption of whole grain foods, including breads, with reduced cardiovascular disease (CVD) risk; however, few studies have compared wheat whole grains with wheat refined gr...

    Authors: Amy J Tucker, Kathryn A MacKay, Lindsay E Robinson, Terry E Graham, Marica Bakovic and Alison M Duncan
    Citation: Nutrition & Metabolism 2010 7:37
  31. The beneficial actions of exercise training on lipid, glucose and energy metabolism and insulin sensitivity appear to be in part mediated by PGC-1α. Previous studies have shown that spontaneously exercised rat...

    Authors: Renata Matiello, Rosa T Fukui, Maria ER Silva, Dalva M Rocha, Bernardo L Wajchenberg, Salman Azhar and Rosa F Santos
    Citation: Nutrition & Metabolism 2010 7:36
  32. Macrophage inhibitory cytokine-1 (MIC-1) is a key inducer of cancer-related anorexia and weight loss. However, its possible role in the etiopathogenesis of nutritional disorders of other etiology such as anore...

    Authors: Ivana Dostálová, Petra Kaválková, Hana Papežová, Daniela Domluvilová, Vít Zikán and Martin Haluzík
    Citation: Nutrition & Metabolism 2010 7:34
  33. Management of glioblastoma multiforme (GBM) has been difficult using standard therapy (radiation with temozolomide chemotherapy). The ketogenic diet is used commonly to treat refractory epilepsy in children an...

    Authors: Giulio Zuccoli, Norina Marcello, Anna Pisanello, Franco Servadei, Salvatore Vaccaro, Purna Mukherjee and Thomas N Seyfried
    Citation: Nutrition & Metabolism 2010 7:33
  34. Despite its use in our diet for hundreds of years, hempseed has surprisingly little research published on its physiological effects. This may have been in the past because the psychotropic properties wrongly a...

    Authors: Delfin Rodriguez-Leyva and Grant N Pierce
    Citation: Nutrition & Metabolism 2010 7:32
  35. Carnitine is a conditionally essential nutrient that plays a vital role in energy production and fatty acid metabolism. Vegetarians possess a greater bioavailability than meat eaters. Distinct deficiencies ari...

    Authors: Judith L Flanagan, Peter A Simmons, Joseph Vehige, Mark DP Willcox and Qian Garrett
    Citation: Nutrition & Metabolism 2010 7:30
  36. The prevalence of Metabolic Syndrome and related chronic diseases, among them non-insulin-dependent (type 2) diabetes mellitus, are on the rise in the United States and throughout the world. Animal models that...

    Authors: Fadi Chaabo, Andrzej Pronczuk, Ekaterina Maslova and KC Hayes
    Citation: Nutrition & Metabolism 2010 7:29
  37. The prevalence of type 2 diabetes is higher among African Americans (AA) vs European Americans (EA), independent of obesity and other known confounders. Although the reason for this disparity is not known, it ...

    Authors: Jessica A Alvarez, Nikki C Bush, Suzanne S Choquette, Gary R Hunter, Betty E Darnell, Robert A Oster and Barbara A Gower
    Citation: Nutrition & Metabolism 2010 7:28
  38. Omentin-1 is a novel adipokine expressed in visceral adipose tissue and negatively associated with insulin resistance and obesity. We aimed to study the effects of weight loss-induced improved insulin sensitiv...

    Authors: José María Moreno-Navarrete, Victoria Catalán, Francisco Ortega, Javier Gómez-Ambrosi, Wifredo Ricart, Gema Frühbeck and José Manuel Fernández-Real
    Citation: Nutrition & Metabolism 2010 7:27
  39. We have recently determined the optimal cut-off of the homeostatic model assessment of insulin resistance for the diagnosis of insulin resistance (IR) and metabolic syndrome (MetS) in non-diabetic residents of...

    Authors: Alireza Esteghamati, Haleh Ashraf, Omid Khalilzadeh, Ali Zandieh, Manouchehr Nakhjavani, Armin Rashidi, Mehrdad Haghazali and Fereshteh Asgari
    Citation: Nutrition & Metabolism 2010 7:26
  40. Previous epidemiological investigations of associations between dietary glycemic intake and insulin resistance have used average daily measures of glycemic index (GI) and glycemic load (GL). We explored multip...

    Authors: Therese A O'Sullivan, Alexandra P Bremner, Sheila O'Neill and Philippa Lyons-Wall
    Citation: Nutrition & Metabolism 2010 7:25
  41. Relatively little is known about the role of specific saturated fatty acids in the development of high fat diet induced obesity and insulin resistance. Here, we have studied the effect of stearate in high fat ...

    Authors: Sjoerd AA van den Berg, Bruno Guigas, Silvia Bijland, Margriet Ouwens, Peter J Voshol, Rune R Frants, Louis M Havekes, Johannes A Romijn and Ko Willems van Dijk
    Citation: Nutrition & Metabolism 2010 7:24
  42. Gamma-oryzanol (OR), a phytosteryl ferulate mixture extracted from rice bran oil, has a wide spectrum of biological activities in particular, it has antioxidant properties.

    Authors: Maznah Ismail, Ghanya Al-Naqeeb, Wan Abd Azizbin Mamat and Zalinah Ahmad
    Citation: Nutrition & Metabolism 2010 7:23
  43. Dual-energy x-ray absorptiometry (DXA) provides an affordable and practical assessment of multiple whole body and regional body composition. However, little information is available on the assessment of change...

    Authors: Diana A Santos, Analiza M Silva, Catarina N Matias, David A Fields, Steven B Heymsfield and Luís B Sardinha
    Citation: Nutrition & Metabolism 2010 7:22
  44. A preventive role of selenium on the risk of diabetes has been reported and ascribed to the "insulin-like" activity of selenium and the antioxidant properties of the selenoenzymes. By contrast, data from cross...

    Authors: Tasnime N Akbaraly, Josiane Arnaud, Margaret P Rayman, Isabelle Hininger-Favier, Anne-Marie Roussel, Claudine Berr and Annick Fontbonne
    Citation: Nutrition & Metabolism 2010 7:21

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