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  1. Content type: Research

    Metabolic abnormalities are more associated with central obesity than peripheral obesity, but the underlying mechanisms are largely unknown. The present study was to identify serum metabolic biomarkers which d...

    Authors: Xiang Gao, Weidong Zhang, Yongbo Wang, Pardis Pedram, Farrell Cahill, Guangju Zhai, Edward Randell, Wayne Gulliver and Guang Sun

    Citation: Nutrition & Metabolism 2016 13:33

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  2. Content type: Research

    Apple polyphenols could represent a novel nutritional approach in the management and control of blood glucose, especially in type 2 diabetics. The aim of this study was to test the therapeutic potential of an ...

    Authors: Manuel Manzano, María D Giron, José D. Vilchez, Natalia Sevillano, Nuri El-Azem, Ricardo Rueda, Rafael Salto and Jose M. Lopez-Pedrosa

    Citation: Nutrition & Metabolism 2016 13:32

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  3. Content type: Research

    Intestinal fatty-acid binding protein (I-FABP) is expressed in epithelial cells of the mucosal layer of the small intestine tissue. When intestinal mucosal damage occurs, I-FABP is released into the circulatio...

    Authors: Eva Lau, Cláudia Marques, Diogo Pestana, Mariana Santoalha, Davide Carvalho, Paula Freitas and Conceição Calhau

    Citation: Nutrition & Metabolism 2016 13:31

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  4. Content type: Research

    Obesity is one of the greatest public health problems and major risk factors for serious metabolic diseases and significantly increases the risk of premature death. The aim of this study was to determine the i...

    Authors: Min-Sup Jung, Soo-Jung Lee, Yuno Song, Sun-Hee Jang, Wongi Min, Chung-Kil Won, Hong-Duck Kim, Tae Hoon Kim and Jae-Hyeon Cho

    Citation: Nutrition & Metabolism 2016 13:29

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  5. Content type: Review

    Hydroxycinnamic acid derivatives are important class of polyphenolic compounds originated from the Mavolanate-Shikimate biosynthesis pathways in plants. Several simple phenolic compounds such as cinnamic acid, p-...

    Authors: Md Ashraful Alam, Nusrat Subhan, Hemayet Hossain, Murad Hossain, Hasan Mahmud Reza, Md Mahbubur Rahman and M Obayed Ullah

    Citation: Nutrition & Metabolism 2016 13:27

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  6. Content type: Research

    Little is known about the effects of dietary components on the regulation of the gastric emptying rate of alcohol and its impact on alcohol metabolism. We recently found that the crude water-insoluble dietary ...

    Authors: Shunji Oshima, Sachie Shiiya, Yoshimi Tokumaru and Tomomasa Kanda

    Citation: Nutrition & Metabolism 2016 13:25

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  7. Content type: Research

    Current criterion of waist circumference (WC) for abdominal obesity is not enough to demonstrate characteristics of obese and non-obese populations defined by BMI. The aim of this study was to redefine the cut...

    Authors: Kyung-Soo Kim, Hyun-Ju Oh, Young Ju Choi, Byung Wook Huh, Soo-Kyung Kim, Seok Won Park, Eun Jig Lee, Yong-Wook Cho and Kap-Bum Huh

    Citation: Nutrition & Metabolism 2016 13:26

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  8. Content type: Research

    Cholesterol accumulation causes pancreatic beta cell lipotoxicity and dysfunction. Cholesteryl ester transfer protein (CETP) plays an important role in blood lipid homeostasis. However, its role in tissue lipi...

    Authors: Wen Guo, Yingyun Gong, Zhenzhen Fu, Jinxiang Fu, Yan Sun, Xianxia Ju, Yina Chang, Wen Wang, Xiaohui Zhu, Beibei Gao, Xiaoyun Liu, Tao Yang and Hongwen Zhou

    Citation: Nutrition & Metabolism 2016 13:21

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  9. Content type: Research

    The liver is an important site of fat oxidation, which participates in the metabolic regulation of food intake. We showed previously that mice with genetically inactivated Acads, encoding short-chain acyl-CoA deh...

    Authors: Sujoy Ghosh, Claudia Kruger, Shawna Wicks, Jacob Simon, K. Ganesh Kumar, William D. Johnson, Randall L. Mynatt, Robert C. Noland and Brenda K. Richards

    Citation: Nutrition & Metabolism 2016 13:17

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  10. Content type: Research

    There is currently no standard clinical refeeding diet for the treatment of anorexia nervosa (AN). To provide the most efficacious AN clinical care, it is necessary to define the metabolic effects of current r...

    Authors: Erin D. Giles, Jennifer Hagman, Zhaoxing Pan, Paul S. MacLean and Janine A. Higgins

    Citation: Nutrition & Metabolism 2016 13:18

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  11. Content type: Brief communication

    Insulin regulates glucose homeostasis through direct effects on the liver, among other organs, with leptin modulating insulin’s hepatic actions. Since central leptin may modify insulin signaling in the liver, ...

    Authors: Emma Burgos-Ramos, Sandra Canelles, Laura M. Frago, Julie A. Chowen, Eduardo Arilla-Ferreiro, Jesús Argente and Vicente Barrios

    Citation: Nutrition & Metabolism 2016 13:19

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  12. Content type: Research

    Type 2 diabetes is associated with increased plasma concentrations of non-esterified fatty acids (NEFAs), which trigger pancreatic β-cell dysfunction and apoptosis. Only long-chain saturated NEFAs induced lipo...

    Authors: Thomas Plötz, Magnus Hartmann, Sigurd Lenzen and Matthias Elsner

    Citation: Nutrition & Metabolism 2016 13:16

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  13. Content type: Research

    As a result of the increased consumption of sugar-rich and fatty-products, and the increase in preference for such products, metabolic disorders are becoming more common at a younger age. Fructose is particula...

    Authors: Iona Lozano, Remmelt Van der Werf, William Bietiger, Elodie Seyfritz, Claude Peronet, Michel Pinget, Nathalie Jeandidier, Elisa Maillard, Eric Marchioni, Séverine Sigrist and Stéphanie Dal

    Citation: Nutrition & Metabolism 2016 13:15

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  14. Content type: Review

    The worldwide prevalence of obesity more than doubled between 1980 and 2014. The obesity pandemic is tightly linked to an increase in energy availability, sedentariness and greater control of ambient temperatu...

    Authors: Nazarii Kobyliak, Caterina Conte, Giovanni Cammarota, Andreana P. Haley, Igor Styriak, Ludovit Gaspar, Jozef Fusek, Luis Rodrigo and Peter Kruzliak

    Citation: Nutrition & Metabolism 2016 13:14

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  15. Content type: Research

    Resistant glucan (RG) and hydrogenated resistant glucan (HRG) are new dietary fiber materials developed to decrease the risk of metabolic syndrome and lifestyle-related diseases. We investigated the metabolism...

    Authors: Sadako Nakamura, Kenichi Tanabe, Shigeki Morita, Norihisa Hamaguchi, Fumio Shimura and Tsuneyuki Oku

    Citation: Nutrition & Metabolism 2016 13:13

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  16. Content type: Research

    The brain is by far the most metabolically active organ in the body, with overall energy expenditure and local blood-supply closely related to neural activity. Both energy metabolism and cerebral vaso-dilation...

    Authors: David O. Kennedy, Emma J. Stevenson, Philippa A. Jackson, Sarah Dunn, Karl Wishart, Gregor Bieri, Luca Barella, Alexandra Carne, Fiona L. Dodd, Bernadette C. Robertson, Joanne Forster and Crystal F. Haskell-Ramsay

    Citation: Nutrition & Metabolism 2016 13:11

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  17. Content type: Research

    Many people believe in favourable effects of branched-chain amino acids (BCAAs; valine, leucine, and isoleucine), especially leucine, on muscle protein balance and consume BCAAs for many years. We determined t...

    Authors: Milan Holecek, Pavel Siman, Melita Vodenicarovova and Roman Kandar

    Citation: Nutrition & Metabolism 2016 13:12

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  18. Content type: Research

    The treatment of Irritable bowel syndrome (IBS) is still challenging. Partially hydrolyzed guar gum (PHGG) is a known prebiotic fiber. To assess the effects of PHGG on clinical symptoms of IBS patients in a pr...

    Authors: E. Niv, A. Halak, E. Tiommny, H. Yanai, H. Strul, T. Naftali and N. Vaisman

    Citation: Nutrition & Metabolism 2016 13:10

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  19. Content type: Research

    Nutritional ketosis induced by the ketogenic diet (KD) has therapeutic applications for many disease states. We hypothesized that oral administration of exogenous ketone supplements could produce sustained nut...

    Authors: Shannon L. Kesl, Angela M. Poff, Nathan P. Ward, Tina N. Fiorelli, Csilla Ari, Ashley J. Van Putten, Jacob W. Sherwood, Patrick Arnold and Dominic P. D’Agostino

    Citation: Nutrition & Metabolism 2016 13:9

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