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  1. Content type: Research

    Renal interstitial fibrosis is a common final pathological process in the progression of kidney disease. This is primarily due to oxidative stress, which contributes to renal inflammation and fibrosis. Nuclear...

    Authors: Sungjin Chung, Hye Eun Yoon, Soo Jeong Kim, Sung Jun Kim, Eun Sil Koh, Yu Ah Hong, Cheol Whee Park, Yoon Sik Chang and Seok Joon Shin

    Citation: Nutrition & Metabolism 2014 11:2

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  2. Content type: Research

    Phenolic acids are covalently bound to the arabinoxylan fibre matrix of wheat aleurone layer. In order to be bioavailable they need to be released by endogenous or bacterial enzymes and absorbed within the int...

    Authors: Jenna Pekkinen, Natalia N Rosa, Otto-Ilari Savolainen, Pekka Keski-Rahkonen, Hannu Mykkänen, Kaisa Poutanen, Valérie Micard and Kati Hanhineva

    Citation: Nutrition & Metabolism 2014 11:1

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  3. Content type: Research

    African-Americans are more insulin-resistant than whites but have lower triglyceride (TG) concentrations. The metabolic basis for this is unknown. Our goal was to determine in a cross-sectional study the effec...

    Authors: Anne E Sumner, Jeremy D Furtado, Amber B Courville, Madia Ricks, Novie Younger-Coleman, Marshall K Tulloch-Reid and Frank M Sacks

    Citation: Nutrition & Metabolism 2013 10:73

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  4. Content type: Research

    Mixing a small proportion, 10%, of retinoic acid (RA) into an oral dose of vitamin A (VA) has been shown to markedly increase retinol uptake and retinyl ester (RE) formation in the neonatal lung, as compared t...

    Authors: Lili Wu, Reza Zolfaghari and A Catharine Ross

    Citation: Nutrition & Metabolism 2013 10:72

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  5. Content type: Review

    Caffeine, nicotine, ethanol and tetrahydrocannabinol (THC) are among the most prevalent and culturally accepted drugs in western society. For example, in Europe and North America up to 90% of the adult populat...

    Authors: Dominik H Pesta, Siddhartha S Angadi, Martin Burtscher and Christian K Roberts

    Citation: Nutrition & Metabolism 2013 10:71

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  6. Content type: Research

    There is completely no report about both hen egg anti-lipase immunoglobulin yolk (IgY) and its anti-obesity action. Thus, we tried to isolate and characterize a novel anti-lipase immunoglobulin from hen egg yo...

    Authors: Mai Hirose, Taishi Ando, Rahman Shofiqur, Kouji Umeda, Yoshikatsu Kodama, Sa Van Nguyen, Tsuyoshi Goto, Masaya Shimada and Satoshi Nagaoka

    Citation: Nutrition & Metabolism 2013 10:70

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  7. Content type: Research

    Serum 25-hydroxyvitamin D (25(OH)D) concentrations associate with skeletal muscle weakness (i.e., deficit in skeletal muscle strength) after muscular injury or damage. Although supplemental vitamin D increases...

    Authors: Tyler Barker, Erik D Schneider, Brian M Dixon, Vanessa T Henriksen and Lindell K Weaver

    Citation: Nutrition & Metabolism 2013 10:69

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  8. Content type: Research

    Elevated homocysteine is a cardiovascular risk factor in hyperlipidemia. Transsulfuration pathway provides an endogenous pathway for homocysteine conversion to antioxidant glutathione (GSH). Salvianolic acid A...

    Authors: Wenting Zhang, Hua He, Haidong Wang, Shijun Wang, Xi Li, Yao Liu, Huiyong Jiang, Hao Jiang, Yidan Yan, Yixuan Wang and Xiaoquan Liu

    Citation: Nutrition & Metabolism 2013 10:68

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  9. Content type: Brief communication

    The protective effect of HDL is mostly attributed to their metabolic function in reverse cholesterol transport (RCT), a process whereby excess cellular cholesterol is taken up from peripheral cells, processed ...

    Authors: Laeticia Lichtenstein, Nizar Serhan, Wijtske Annema, Guillaume Combes, Bernard Robaye, Jean-Marie Boeynaems, Bertrand Perret, Uwe J F Tietge, Muriel Laffargue and Laurent O Martinez

    Citation: Nutrition & Metabolism 2013 10:67

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  10. Content type: Research

    Zerumbone is one of the pungent constituents of Zingiber zerumbet (L) Smith (Zingiberaceae family). The aim of the present study was to examine the effects of zerumbone in rats with streptozotocin-induced diabeti...

    Authors: Thing-Fong Tzeng, Shorong-Shii Liou, Chia Ju Chang and I-Min Liu

    Citation: Nutrition & Metabolism 2013 10:64

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  11. Content type: Research

    For decades in Finland, intensive population strategies and preventive activities have been used to lower the risk of atherosclerotic coronary heart disease (CHD). Lifestyle changes, with the emphasis on diet,...

    Authors: Maarit Hallikainen, Janne Halonen, Jussi Konttinen, Harri Lindholm, Piia Simonen, Markku J Nissinen and Helena Gylling

    Citation: Nutrition & Metabolism 2013 10:62

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  12. Content type: Perspective

    Milk protein intake has recently been suggested to improve metabolic health. This Perspective provides evidence that metabolic effects of milk protein intake have to be regarded in the context of the individua...

    Authors: Bodo C Melnik, Gerd Schmitz, Swen Malte John, Pedro Carrera-Bastos, Staffan Lindeberg and Loren Cordain

    Citation: Nutrition & Metabolism 2013 10:60

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  13. Content type: Research

    Lower serum total (TC), high-density lipoprotein (HDL-C) and low-density lipoprotein cholesterols (LDL-C) have been linked to an increased risk of cancer in various sites, but its underlying mechanism remains ...

    Authors: Hiroyuki Kikuchi, Akiko Nanri, Ai Hori, Masao Sato, Kazuaki Kawai, Hiroshi Kasai and Tetsuya Mizoue

    Citation: Nutrition & Metabolism 2013 10:59

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  14. Content type: Research

    Low levels of high-density lipoproteins (HDL) are considered an important risk factor for cardiovascular disease and constitute one of the criteria for the Metabolic Syndrome (MetS). Lifestyle interventions pr...

    Authors: Lillian Kent, Darren Morton, Paul Rankin, Ewan Ward, Ross Grant, John Gobble and Hans Diehl

    Citation: Nutrition & Metabolism 2013 10:58

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  15. Content type: Research

    Currently, there is a lack of studies examining the effects of adenosine-5′-triphosphate (ATP) supplementation utilizing a long-term, periodized resistance-training program (RT) in resistance-trained populatio...

    Authors: Jacob M Wilson, Jordan M Joy, Ryan P Lowery, Michael D Roberts, Christopher M Lockwood, Anssi H Manninen, John C Fuller Jr., Eduardo O De Souza, Shawn M Baier, Stephanie MC Wilson and John A Rathmacher

    Citation: Nutrition & Metabolism 2013 10:57

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  16. Content type: Research

    Microsomal triglyceride transfer protein (MTTP) is an essential chaperone that assists in the assembly of apolipoprotein B-containing lipoproteins to transport lipids. We have shown that microRNA (miR)-30c reg...

    Authors: James Soh and M Mahmood Hussain

    Citation: Nutrition & Metabolism 2013 10:56

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  17. Content type: Research

    Previously, we reported that ProAlgaZyme (PAZ) and its biologically active fraction improved plasma lipids in hypercholesterolemic hamsters, by significantly increasing the high density lipoprotein cholesterol...

    Authors: Andreea Geamanu, Arvind Goja, Nadia Saadat, Pramod Khosla and Smiti V Gupta

    Citation: Nutrition & Metabolism 2013 10:55

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  18. Content type: Review

    Epidemiological studies indicate that the consumption of fructose-containing caloric sweeteners (FCCS: mainly sucrose and high-fructose corn syrup) is associated with obesity. The hypothesis that FCCS plays a ...

    Authors: Luc Tappy, Leonie Egli, Virgile Lecoultre and Pascal Schneider

    Citation: Nutrition & Metabolism 2013 10:54

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  19. Content type: Research

    Beneficial effects of glutamine (GLN) have been described in many gastrointestinal disorders. The aim of the present study was to evaluate the preventative effect of oral GLN supplementation against acetic aci...

    Authors: Forat Swaid, Igor Sukhotnik, Ibrahim Matter, Drora Berkowitz, Christopher Hadjittofi, Yulia Pollak and Alexandra Lavy

    Citation: Nutrition & Metabolism 2013 10:53

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  20. Content type: Letter to the Editor

    We examined the methodological approach to the assessment of monosodium glutamate intake. The high carbohydrate and low fat consumption characteristic of this study population would be conducive to the develop...

    Authors: Karuthan Chinna and Tilakavati Karupaiah

    Citation: Nutrition & Metabolism 2013 10:52

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  21. Content type: Research

    It is increasingly being realized that failure of pancreatic beta cells to secrete enough insulin to adequately compensate for obesity and insulin resistance is the primary defects of type 2 diabetes mellitus ...

    Authors: Ye Ding, Zhaofeng Zhang, Xiaoqian Dai, Yanfei Jiang, Lei Bao, Yujie Li and Yong Li

    Citation: Nutrition & Metabolism 2013 10:51

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  22. Content type: Research

    The conjugated linoleic acid isomer cis9trans11 CLA can be endogenously synthesized from trans vaccenic acid (C18:1 t11) via desaturation at the delta 9 position catalyzed by the stearoyl-CoA desaturase 1 (SCD...

    Authors: Salma A Abdelmagid, Shannon E Clarke, Jeremy Wong, Kaitlin Roke, Daiva Nielsen, Alaa Badawi, Ahmed El-Sohemy, David M Mutch and David WL Ma

    Citation: Nutrition & Metabolism 2013 10:50

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  23. Content type: Research

    Disorders such as the metabolic syndrome (MetS), impaired glucose tolerance and diabetes, are associated with increased risk of cognitive decline. Also several of the individual key features that define the Me...

    Authors: Anne Nilsson, Juscelino Tovar, Maria Johansson, Karl Radeborg and Inger Björck

    Citation: Nutrition & Metabolism 2013 10:49

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  24. Content type: Research

    In the present study, we tested the hypothesis that carnitine supplementation counteracts obesity-induced muscle fiber transition from type I to type II.

    Authors: Aline Couturier, Robert Ringseis, Frank-Christoph Mooren, Karsten Krüger, Erika Most and Klaus Eder

    Citation: Nutrition & Metabolism 2013 10:48

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    The Erratum to this article has been published in Nutrition & Metabolism 2014 11:16

  25. Content type: Research

    Recent studies in animal models, based on the hypothesis that malignant glioma cells are more dependent on glycolysis for energy generation, have shown promising results using ketogenic diet (KD) therapy as an...

    Authors: Howard T Chang, Lawrence Karl Olson and Kenneth A Schwartz

    Citation: Nutrition & Metabolism 2013 10:47

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  26. Content type: Review

    Whether dietary fructose (as sucrose or high fructose corn syrup) has unique effects separate from its role as carbohydrate, or, in fact, whether it can be considered inherently harmful, even a toxin, has assu...

    Authors: Richard D Feinman and Eugene J Fine

    Citation: Nutrition & Metabolism 2013 10:45

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  27. Content type: Research

    The human diet has altered markedly during the past four decades, with the introduction of Trans hydrogenated fat, which extended the shelf-life of dietary oils and promoted a dramatic increase in elaidic acid (T...

    Authors: Kate S Collison, Nadine J Makhoul, Marya Z Zaidi, Angela Inglis, Bernard L Andres, Rosario Ubungen, Soad Saleh and Futwan A Al-Mohanna

    Citation: Nutrition & Metabolism 2013 10:44

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  28. Content type: Research

    Although evidence indicates that fatty acids (FA) can affect insulin resistance (IR), not all FA contribute equally to the process. Indeed, monounsaturated FA (MUFA) and polyunsaturated FA (PUFA) are reported ...

    Authors: Jessica C Ralston, Michael A Zulyniak, Daiva E Nielsen, Shannon Clarke, Alaa Badawi, Ahmed El-Sohemy, David WL Ma and David M Mutch

    Citation: Nutrition & Metabolism 2013 10:42

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  29. Content type: Research

    Supplementation studies have suggested a role of n-3 polyunsaturated fatty acids (PUFAs) in homocysteine metabolism, but the evidence is limited and inconsistent among studies that measured blood levels of n-3...

    Authors: Ayami Kume, Kayo Kurotani, Masao Sato, Yuko Ejima, Ngoc Minh Pham, Akiko Nanri, Keisuke Kuwahara and Tetsuya Mizoue

    Citation: Nutrition & Metabolism 2013 10:41

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  30. Content type: Research

    The cardiovascular (CV) and metabolic health benefits or risks associated with consumption of multi-ingredient performance supplements (MIPS) in conjunction with periodized resistance training (RT) in resistan...

    Authors: Michael J Ormsbee, Dennison David Thomas, William Kyle Mandler, Emery G Ward, Amber W Kinsey, Lynn B Panton, Timothy P Scheett, Shirin Hooshmand, Emily Simonavice and Jeong-Su Kim

    Citation: Nutrition & Metabolism 2013 10:39

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  31. Content type: Research

    Both exercise and vitamin E supplementation have been shown to reduce oxidative stress and cardiovascular disease risk in older adults, and when combined there is evidence suggesting that they act synergistica...

    Authors: Jong-Hwan Park, Masashi Miyashita, Masaki Takahashi, Noriaki Kawanishi, Seong-Ryu Bae, Hyun-Shik Kim, Katsuhiko Suzuki and Yoshio Nakamura

    Citation: Nutrition & Metabolism 2013 10:38

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  32. Content type: Research

    Monomethylsilanetriol (MMST) has been used for decades as an oral silicon supplement for bone and connective tissue health, although there are no formal data on its in vivo utilisation or safety following sustain...

    Authors: Ravin Jugdaohsingh, Maio Hui, Simon HC Anderson, Stephen D Kinrade and Jonathan J Powell

    Citation: Nutrition & Metabolism 2013 10:37

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  33. Content type: Brief communication

    Total fat and omega-3 fatty acids in the diet may affect breast cancer risk by altering estrogen metabolism. The purpose of this study was to elucidate the effects of differing total fat and omega-3 fatty acid...

    Authors: Lindsay R Young, Susan K Raatz, William Thomas, J Bruce Redmon and Mindy S Kurzer

    Citation: Nutrition & Metabolism 2013 10:36

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  34. Content type: Research

    Type 2 diabetes mellitus (DM), characterized by peripheral insulin resistance, is the most common form of diabetes. Probiotics are live micro-organisms that, when administered in adequate amounts, confer delay...

    Authors: Feng-Ching Hsieh, Chia-Lin Lee, Chee-Yin Chai, Wan-Tzu Chen, Ying-Chen Lu and Ching-Shuang Wu

    Citation: Nutrition & Metabolism 2013 10:35

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  35. Content type: Review

    Gaucher disease (GD) type I is the most common type of GD. Its main clinical manifestations are hepatosplenomegaly as well as bone and hematological abnormalities. The objective of the present study was to per...

    Authors: Divair Doneda, Cristina B Netto, Cileide C Moulin and Ida Vanessa D Schwartz

    Citation: Nutrition & Metabolism 2013 10:34

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  36. Content type: Research

    Glucagon-like Peptide-1 (GLP-1) is an incretin hormone secreted from the gastrointestinal tract that facilitates the glucose-dependent insulin response. Additionally, GLP-1 is thought to be involved in energy ...

    Authors: Danny Wadden, Farrell Cahill, Peyvand Amini, Edward Randell, Sudesh Vasdev, Yanqing Yi, Jon Church and Guang Sun

    Citation: Nutrition & Metabolism 2013 10:33

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  37. Content type: Research

    Fructose produces hepatic insulin resistance in humans and animals. We have proposed that the selective metabolism of fructose by the liver can, under conditions of elevated fructose delivery, inflict a metabo...

    Authors: Yuren Wei, Dong Wang, Gretchen Moran, Andrea Estrada and Michael J Pagliassotti

    Citation: Nutrition & Metabolism 2013 10:32

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  38. Content type: Review

    Lipid metabolic disorder is a critical risk factor for metabolic syndrome, triggering debilitating diseases like obesity and diabetes. Both obesity and diabetes are the epicenter of important medical issues, r...

    Authors: Sarwar Hashmi, Yi Wang, Ranjit S Parhar, Kate S Collison, Walter Conca, Futwan Al-Mohanna and Randy Gaugler

    Citation: Nutrition & Metabolism 2013 10:31

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  39. Content type: Research

    Metabolic syndrome has become a major public health concern, but the role of diet in the etiology of this syndrome is not well understood. This study investigated the association between major dietary patterns...

    Authors: Shamima Akter, Akiko Nanri, Ngoc Minh Pham, Kayo Kurotani and Tetsuya Mizoue

    Citation: Nutrition & Metabolism 2013 10:30

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  40. Content type: Research

    Obesity is associated with low-grade inflammation and impaired immune response. Caloric restriction (CR) has been shown to inhibit inflammatory response and enhance cell-mediated immune function. Curcumin, the...

    Authors: Junpeng Wang, Sally M Vanegas, Xiaogang Du, Timothy Noble, Jean-Marc A Zingg, Mohsen Meydani, Simin Nikbin Meydani and Dayong Wu

    Citation: Nutrition & Metabolism 2013 10:29

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  41. Content type: Research

    Recently, it has been shown that carnitine down-regulates genes involved in the ubiquitin-proteasome system (UPS) in muscle of pigs and rats. The mechanisms underlying this observation are yet unknown. Based o...

    Authors: Janine Keller, Aline Couturier, Melanie Haferkamp, Erika Most and Klaus Eder

    Citation: Nutrition & Metabolism 2013 10:28

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  42. Content type: Research

    Soy oil is a major vegetable oil consumed in the US. A recently developed soybean variety produces oil with a lower concentration of α-linolenic acid, hence a higher (n-6)/(n-3) ratio, than regular soy oil. Th...

    Authors: Ramesh B Potu, Hang Lu, Olayiwola Adeola and Kolapo M Ajuwon

    Citation: Nutrition & Metabolism 2013 10:27

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  43. Content type: Research

    Visceral fat accumulation is caused by over-nutrition and physical inactivity. Excess accumulation of visceral fat associates with atherosclerosis. Polyunsaturated fatty acids have an important role in human n...

    Authors: Kana Inoue, Ken Kishida, Ayumu Hirata, Tohru Funahashi and Iichiro Shimomura

    Citation: Nutrition & Metabolism 2013 10:25

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