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  1. Sphingomyelin (SM) is the major phospholipid in cell membranes and in lipoproteins. In human plasma, SM is mainly found in atherogenic lipoproteins; thus, high levels of SM may promote atherogenesis.

    Authors: Axel Schlitt, Stefan Blankenberg, Daoguang Yan, Hans von Gizycki, Michael Buerke, Karl Werdan, Christoph Bickel, Karl J Lackner, Juergen Meyer, Hans J Rupprecht and Xian-Cheng Jiang
    Citation: Nutrition & Metabolism 2006 3:5
  2. Impaired vasodilatation has been suggested to be caused by inhibition of nitric oxide generation by the recently described asymmetric dimethylarginine (ADMA). In the present study we wanted to explore whether ...

    Authors: Hilde MA Eid, Harald Arnesen, Elsa M Hjerkinn, Torstein Lyberg, Ingrid Ellingsen and Ingebjørg Seljeflot
    Citation: Nutrition & Metabolism 2006 3:4
  3. Holotranscobalamin, cobalamin-saturated transcobalamin, is the minor fraction of circulating cobalamin (vitamin B12), which is available for cellular uptake and hence is physiologically relevant. Currently, no...

    Authors: Lars Orning, Anne Rian, Andrew Campbell, Jeff Brady, Sergey N Fedosov, Birgit Bramlage, Keith Thompson and Edward V Quadros
    Citation: Nutrition & Metabolism 2006 3:3
  4. We examined aerobic and anaerobic exercise energy expenditure and excess post-exercise oxygen consumption (EPOC) between a 250 Watt, 1-minute bout of cycling and uphill treadmill running.

    Authors: Christopher B Scott, Nathanael D Littlefield, Jeffrey D Chason, Michael P Bunker and Elizabeth M Asselin
    Citation: Nutrition & Metabolism 2006 3:1
  5. Polycystic ovary syndrome (PCOS) is the most common endocrine disorder affecting women of reproductive age and is associated with obesity, hyperinsulinemia, and insulin resistance. Because low carbohydrate die...

    Authors: John C Mavropoulos, William S Yancy, Juanita Hepburn and Eric C Westman
    Citation: Nutrition & Metabolism 2005 2:35
  6. The metabolic function of PEPCK-C is not fully understood; deletion of the gene for the enzyme in mice provides an opportunity to fully assess its function.

    Authors: Parvin Hakimi, Mark T Johnson, Jianqi Yang, David F Lepage, Ronald A Conlon, Satish C Kalhan, Lea Reshef, Shirley M Tilghman and Richard W Hanson
    Citation: Nutrition & Metabolism 2005 2:33
  7. There is an emerging theory suggesting that insulin, which is known to be the predominant postprandial anabolic hormone, is also a major regulator of mitochondrial oxidative phosphorylation in human skeletal m...

    Authors: Laurence Baillet-Blanco, Marie-Christine Beauvieux, Henri Gin, Vincent Rigalleau and Jean-Louis Gallis
    Citation: Nutrition & Metabolism 2005 2:32
  8. Metabolic Syndrome (MetS) represents a constellation of markers that indicates a predisposition to diabetes, cardiovascular disease and other pathologic states. The definition and treatment are a matter of cur...

    Authors: Jeff S Volek and Richard D Feinman
    Citation: Nutrition & Metabolism 2005 2:31
  9. Alzheimer's disease (AD) is a progressive neurodegenerative disorder that primarily strikes the elderly. Studies in both humans and animal models have linked the consumption of cholesterol and saturated fats w...

    Authors: Ingrid Van der Auwera, Stefaan Wera, Fred Van Leuven and Samuel T Henderson
    Citation: Nutrition & Metabolism 2005 2:28
  10. We have previously reported that rheumatoid arthritis patients, who adopted a modified Cretan Mediterranean diet, obtained a reduction in disease activity and an improvement in physical function and vitality. ...

    Authors: Linda Hagfors, Ingela Nilsson, Lars Sköldstam and Gunnar Johansson
    Citation: Nutrition & Metabolism 2005 2:26
  11. Recent trends in weight loss diets have led to a substantial increase in protein intake by individuals. As a result, the safety of habitually consuming dietary protein in excess of recommended intakes has been...

    Authors: William F Martin, Lawrence E Armstrong and Nancy R Rodriguez
    Citation: Nutrition & Metabolism 2005 2:25
  12. Epidemiological studies have linked low dietary magnesium (Mg) to low bone mineral density and osteoporosis. Mg deficiency in animal models has demonstrated a reduction in bone mass and increase in skeletal fr...

    Authors: Robert K Rude, Helen E Gruber, Livia Y Wei and Angelica Frausto
    Citation: Nutrition & Metabolism 2005 2:24
  13. Studies on the effects of (-)-hydroxycitric acid (HCA) in humans are controversial. As differences in the HCA preparations may contribute to this apparent discrepancy, the aim of the current study is to compar...

    Authors: Johanna Louter-van de Haar, Peter Y Wielinga, Anton JW Scheurink and Arie G Nieuwenhuizen
    Citation: Nutrition & Metabolism 2005 2:23
  14. Melatonin, originally discovered as a hormone of the pineal gland, is also produced in other organs and represents, additionally, a normal food constituent found in yeast and plant material, which can influenc...

    Authors: Rüdiger Hardeland and SR Pandi-Perumal
    Citation: Nutrition & Metabolism 2005 2:22
  15. Unloading of skeletal muscle causes atrophy and loss of contractile function. In part, this response is believed to be mediated by the transcription factor nuclear factor-kappa B (NF-κB). Both curcumin, a comp...

    Authors: Mehran Farid, Michael B Reid, Yi-Ping Li, Eric Gerken and William J Durham
    Citation: Nutrition & Metabolism 2005 2:20
  16. The Family Blood Pressure Program is an ongoing, NHLBI-sponsored, multi-center program to study the genetic determinants of high blood pressure. The goal of this particular study was to study patterns of metab...

    Authors: Aldi T Kraja, DC Rao, Alan B Weder, Thomas H Mosley, Stephen T Turner, Chao Agnes Hsiung, Thomas Quertermous, Richard Cooper, J David Curb and Michael A Province
    Citation: Nutrition & Metabolism 2005 2:17
  17. A low fat, high carbohydrate diet in combination with regular exercise is the traditional recommendation for treating diabetes. Compliance with these lifestyle modifications is less than satisfactory, however,...

    Authors: Surender K Arora and Samy I McFarlane
    Citation: Nutrition & Metabolism 2005 2:16
  18. Obesity is associated with insulin resistance that can often be improved by caloric restriction and weight reduction. Although many physiological changes accompanying insulin resistance and its treatment have ...

    Authors: R Michael Raab, John Bullen, Joanne Kelleher, Christos Mantzoros and Gregory Stephanopoulos
    Citation: Nutrition & Metabolism 2005 2:15
  19. Plasma total homocysteine (tHcy) is commonly elevated in persons with diabetes. This may be due to effects of insulin and/or glucose and/or metabolic control on the metabolism or plasma levels of tHcy. This st...

    Authors: Glen E Duncan, Sierra M Li and Xiao-Hua Zhou
    Citation: Nutrition & Metabolism 2005 2:13
  20. Energy and Zinc (Zn) deficiencies have been associated with nutritional related growth retardation as well as growth hormone (GH) resistance. In this study, the relationship between suboptimal energy and/or Zn...

    Authors: Russell Rising, Julio F Scaglia, Conrad Cole, Rozalia Tverskaya, Debora Duro and Fima Lifshitz
    Citation: Nutrition & Metabolism 2005 2:10
  21. Osteoporosis is a major public health problem with low bone mass affecting nearly half the women aged 50 years or older. Evidence from various studies has shown that higher body mass index (BMI) is a protectiv...

    Authors: Jonathan P Castro, Linda A Joseph, John J Shin, Surender K Arora, John Nicasio, Joshua Shatzkes, Irina Raklyar, Irina Erlikh, Vincent Pantone, Gul Bahtiyar, Leon Chandler, Lina Pabon, Sara Choudhry, Nilofar Ghadiri, Pramodini Gosukonda, Rangnath Muniyappa…
    Citation: Nutrition & Metabolism 2005 2:9
  22. Cholesterol ester transfer protein (CETP) plays a major role in regulating the levels of LDL- and HDL-cholesterol. We previously observed a fish-oil-induced elevation of low-density lipoprotein (LDL)-and very-...

    Authors: Pujitha P de Silva, Alka Agarwal-Mawal, Phillip J Davis and Sukhinder Kaur Cheema
    Citation: Nutrition & Metabolism 2005 2:8
  23. Although feeding deficits have been reported in snakes and lizards following vomeronasal system disruption, no deficit has been previously reported in a mammal. We tested gray short-tailed opossums with items ...

    Authors: Mimi Halpern, Yasmine Daniels and Ido Zuri
    Citation: Nutrition & Metabolism 2005 2:6
  24. Obesity and type 2 diabetes are occurring at epidemic rates in the United States and many parts of the world. The "obesity epidemic" appears to have emerged largely from changes in our diet and reduced physica...

    Authors: Heather Basciano, Lisa Federico and Khosrow Adeli
    Citation: Nutrition & Metabolism 2005 2:5
  25. Ancel Keys, Ph.D., who died in November, 2004, at the age of 100, was among the first scientists to recognize that human atherosclerosis is not an inevitable consequence of aging, and that a high-fat diet can ...

    Authors: Theodore B VanItallie
    Citation: Nutrition & Metabolism 2005 2:4
  26. In 2001 the National Cholesterol Education Program (NCEP) provided a categorical definition for metabolic syndrome (c-MetS). We studied the extent to which two ethnic groups, Blacks and Whites were affected by...

    Authors: Aldi T Kraja, Steven C Hunt, James S Pankow, Richard H Myers, Gerardo Heiss, Cora E Lewis, DC Rao and Michael A Province
    Citation: Nutrition & Metabolism 2005 2:2
  27. Phytoestrogens derived from soy foods (or isoflavones) have received prevalent usage due to their 'health benefits' of decreasing: a) age-related diseases, b) hormone-dependent cancers and c) postmenopausal sy...

    Authors: Edwin D Lephart, James P Porter, Trent D Lund, Lihong Bu, Kenneth DR Setchell, Gina Ramoz and William R Crowley
    Citation: Nutrition & Metabolism 2004 1:16
  28. It is commonly held that "a calorie is a calorie", i.e. that diets of equal caloric content will result in identical weight change independent of macronutrient composition, and appeal is frequently made to the...

    Authors: Eugene J Fine and Richard D Feinman
    Citation: Nutrition & Metabolism 2004 1:15
  29. To compare the effects of isocaloric, energy-restricted very low-carbohydrate ketogenic (VLCK) and low-fat (LF) diets on weight loss, body composition, trunk fat mass, and resting energy expenditure (REE) in o...

    Authors: JS Volek, MJ Sharman, AL Gómez, DA Judelson, MR Rubin, G Watson, B Sokmen, R Silvestre, DN French and WJ Kraemer
    Citation: Nutrition & Metabolism 2004 1:13
  30. There are likely many scenarios and pathways that can lead to metabolic syndrome. This paper reviews mechanisms by which the accumulation of visceral adipose tissue (VAT) may contribute to the metabolic syndro...

    Authors: Eric S Freedland
    Citation: Nutrition & Metabolism 2004 1:12
  31. The high fat, low carbohydrate ketogenic diet (KD) was developed as an alternative to fasting for seizure management. While the mechanisms by which fasting and the KD inhibit seizures remain speculative, alter...

    Authors: John G Mantis, Nicole A Centeno, Mariana T Todorova, Richard McGowan and Thomas N Seyfried
    Citation: Nutrition & Metabolism 2004 1:11
  32. The topical role of uric acid and its relation to cardiovascular disease, renal disease, and hypertension is rapidly evolving. Its important role both historically and currently in the clinical clustering phen...

    Authors: Melvin R Hayden and Suresh C Tyagi
    Citation: Nutrition & Metabolism 2004 1:10
  33. Epidemiological studies suggest a non-monotonic effect of alcohol consumption on cardiovascular risk, while there is strong evidence concerning the involvement of homocysteine levels on thrombosis. The aim of ...

    Authors: Christos Pitsavos, Demosthenes B Panagiotakos, Meropi D Kontogianni, Christina Chrysohoou, Yannis Chloptsios, Antonis Zampelas, Antonia Trichopoulou and Christodoulos Stefanadis
    Citation: Nutrition & Metabolism 2004 1:9
  34. Although the effects of resistant starch (RS) on postprandial glycemia and insulinemia have been extensively studied, little is known about the impact of RS on fat metabolism. This study examines the relations...

    Authors: Janine A Higgins, Dana R Higbee, William T Donahoo, Ian L Brown, Melanie L Bell and Daniel H Bessesen
    Citation: Nutrition & Metabolism 2004 1:8
  35. Following a low carbohydrate diet, there is a shift towards more fat and less carbohydrate oxidation to provide energy to skeletal muscle, both at rest and during exercise. This review summarizes recent work o...

    Authors: Sandra J Peters and Paul J LeBlanc
    Citation: Nutrition & Metabolism 2004 1:7

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