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  1. Diets that restrict carbohydrate (CHO) have proven to be a successful dietary treatment of obesity for many people, but the degree of weight loss varies across individuals. The extent to which genetic factors ...

    Authors: Gualberto Ruaño, Andreas Windemuth, Mohan Kocherla, Theodore Holford, Maria Luz Fernandez, Cassandra E Forsythe, Richard J Wood, William J Kraemer and Jeff S Volek
    Citation: Nutrition & Metabolism 2006 3:20
  2. Increasing evidence supports carbohydrate restricted diets (CRD) for weight loss and improvement in traditional markers for cardiovascular disease (CVD); less is known regarding emerging CVD risk factors. We p...

    Authors: Richard J Wood, Jeff S Volek, Steven R Davis, Carly Dell'Ova and Maria Luz Fernandez
    Citation: Nutrition & Metabolism 2006 3:19
  3. Asian Indian immigrants have an increased risk for developing cardiovascular disease (CVD); however, there is very little data examining how the adipokines leptin and adiponectin relate to CVD risk factors suc...

    Authors: Jessica Smith, Maha Al-Amri, Allan Sniderman and Katherine Cianflone
    Citation: Nutrition & Metabolism 2006 3:18
  4. We studied the regulation of brain acetyl CoA carboxylase (ACC) activity during food deprivation and under the influence of hormones of glucose homeostasis: glucagon and insulin. Mice were deprived of food and...

    Authors: Kristophe J Karami, John Coppola, Karthik Krishnamurthy, Domingo J Llanos, Amrita Mukherjee and KV Venkatachalam
    Citation: Nutrition & Metabolism 2006 3:15
  5. The determinants of bone mineral density (BMD) at multiple sites were examined in a fit college population. Subjects were 755 males (mean age = 18.7 years) entering the United States Military Academy. A questi...

    Authors: JA Ruffing, F Cosman, M Zion, Susan Tendy, P Garrett, R Lindsay and JW Nieves
    Citation: Nutrition & Metabolism 2006 3:14
  6. Thyroid abnormalities (hyperthyroid and hypothyroid) are accompanied by changes in intermediary metabolism including alterations in body weight, insulin resistance and lipid profile. The aims of this study wer...

    Authors: Haiying Yu, Yan Yang, Muxun Zhang, Huiling Lu, Jianhua Zhang, Hongwei Wang and Katherine Cianflone
    Citation: Nutrition & Metabolism 2006 3:13
  7. All treatments for obesity, including dietary restriction of carbohydrates, have a goal of reducing the storage of fat in adipocytes. The chief enzyme responsible for the mobilization of FFA from adipose tissu...

    Authors: Fredric B Kraemer and Wen-Jun Shen
    Citation: Nutrition & Metabolism 2006 3:12
  8. Conjugated linoleic acid (CLA) is a group of polyunsaturated fatty acids which have been extensively studied in the past two decades. However, conjugated octadecatrienoic acid such as cis-9,trans-11,cis-15 and ci...

    Authors: Mélanie Plourde, Jean-Pierre Sergiel, Jean-Michel Chardigny, Stéphane Grégoire, Paul Angers and Jean-Louis Sébédio
    Citation: Nutrition & Metabolism 2006 3:8
  9. It is speculated that high saturated fat very low carbohydrate diets (VLCARB) have adverse effects on cardiovascular risk but evidence for this in controlled studies is lacking. The objective of this study was...

    Authors: Manny Noakes, Paul R Foster, Jennifer B Keogh, Anthony P James, John C Mamo and Peter M Clifton
    Citation: Nutrition & Metabolism 2006 3:7
  10. Approximately 1/3 of individuals have a high plasma response to dietary cholesterol (hyper-responders). Although increases in both LDL and HDL cholesterol have been observed, limited data exist regarding effec...

    Authors: Christine M Greene, David Waters, Richard M Clark, John H Contois and Maria Luz Fernandez
    Citation: Nutrition & Metabolism 2006 3:6
  11. Sphingomyelin (SM) is the major phospholipid in cell membranes and in lipoproteins. In human plasma, SM is mainly found in atherogenic lipoproteins; thus, high levels of SM may promote atherogenesis.

    Authors: Axel Schlitt, Stefan Blankenberg, Daoguang Yan, Hans von Gizycki, Michael Buerke, Karl Werdan, Christoph Bickel, Karl J Lackner, Juergen Meyer, Hans J Rupprecht and Xian-Cheng Jiang
    Citation: Nutrition & Metabolism 2006 3:5
  12. Impaired vasodilatation has been suggested to be caused by inhibition of nitric oxide generation by the recently described asymmetric dimethylarginine (ADMA). In the present study we wanted to explore whether ...

    Authors: Hilde MA Eid, Harald Arnesen, Elsa M Hjerkinn, Torstein Lyberg, Ingrid Ellingsen and Ingebjørg Seljeflot
    Citation: Nutrition & Metabolism 2006 3:4
  13. Holotranscobalamin, cobalamin-saturated transcobalamin, is the minor fraction of circulating cobalamin (vitamin B12), which is available for cellular uptake and hence is physiologically relevant. Currently, no...

    Authors: Lars Orning, Anne Rian, Andrew Campbell, Jeff Brady, Sergey N Fedosov, Birgit Bramlage, Keith Thompson and Edward V Quadros
    Citation: Nutrition & Metabolism 2006 3:3
  14. We examined aerobic and anaerobic exercise energy expenditure and excess post-exercise oxygen consumption (EPOC) between a 250 Watt, 1-minute bout of cycling and uphill treadmill running.

    Authors: Christopher B Scott, Nathanael D Littlefield, Jeffrey D Chason, Michael P Bunker and Elizabeth M Asselin
    Citation: Nutrition & Metabolism 2006 3:1
  15. Polycystic ovary syndrome (PCOS) is the most common endocrine disorder affecting women of reproductive age and is associated with obesity, hyperinsulinemia, and insulin resistance. Because low carbohydrate die...

    Authors: John C Mavropoulos, William S Yancy, Juanita Hepburn and Eric C Westman
    Citation: Nutrition & Metabolism 2005 2:35
  16. The metabolic function of PEPCK-C is not fully understood; deletion of the gene for the enzyme in mice provides an opportunity to fully assess its function.

    Authors: Parvin Hakimi, Mark T Johnson, Jianqi Yang, David F Lepage, Ronald A Conlon, Satish C Kalhan, Lea Reshef, Shirley M Tilghman and Richard W Hanson
    Citation: Nutrition & Metabolism 2005 2:33
  17. There is an emerging theory suggesting that insulin, which is known to be the predominant postprandial anabolic hormone, is also a major regulator of mitochondrial oxidative phosphorylation in human skeletal m...

    Authors: Laurence Baillet-Blanco, Marie-Christine Beauvieux, Henri Gin, Vincent Rigalleau and Jean-Louis Gallis
    Citation: Nutrition & Metabolism 2005 2:32
  18. Metabolic Syndrome (MetS) represents a constellation of markers that indicates a predisposition to diabetes, cardiovascular disease and other pathologic states. The definition and treatment are a matter of cur...

    Authors: Jeff S Volek and Richard D Feinman
    Citation: Nutrition & Metabolism 2005 2:31
  19. Alzheimer's disease (AD) is a progressive neurodegenerative disorder that primarily strikes the elderly. Studies in both humans and animal models have linked the consumption of cholesterol and saturated fats w...

    Authors: Ingrid Van der Auwera, Stefaan Wera, Fred Van Leuven and Samuel T Henderson
    Citation: Nutrition & Metabolism 2005 2:28
  20. We have previously reported that rheumatoid arthritis patients, who adopted a modified Cretan Mediterranean diet, obtained a reduction in disease activity and an improvement in physical function and vitality. ...

    Authors: Linda Hagfors, Ingela Nilsson, Lars Sköldstam and Gunnar Johansson
    Citation: Nutrition & Metabolism 2005 2:26
  21. Recent trends in weight loss diets have led to a substantial increase in protein intake by individuals. As a result, the safety of habitually consuming dietary protein in excess of recommended intakes has been...

    Authors: William F Martin, Lawrence E Armstrong and Nancy R Rodriguez
    Citation: Nutrition & Metabolism 2005 2:25
  22. Epidemiological studies have linked low dietary magnesium (Mg) to low bone mineral density and osteoporosis. Mg deficiency in animal models has demonstrated a reduction in bone mass and increase in skeletal fr...

    Authors: Robert K Rude, Helen E Gruber, Livia Y Wei and Angelica Frausto
    Citation: Nutrition & Metabolism 2005 2:24
  23. Studies on the effects of (-)-hydroxycitric acid (HCA) in humans are controversial. As differences in the HCA preparations may contribute to this apparent discrepancy, the aim of the current study is to compar...

    Authors: Johanna Louter-van de Haar, Peter Y Wielinga, Anton JW Scheurink and Arie G Nieuwenhuizen
    Citation: Nutrition & Metabolism 2005 2:23
  24. Melatonin, originally discovered as a hormone of the pineal gland, is also produced in other organs and represents, additionally, a normal food constituent found in yeast and plant material, which can influenc...

    Authors: Rüdiger Hardeland and SR Pandi-Perumal
    Citation: Nutrition & Metabolism 2005 2:22
  25. Unloading of skeletal muscle causes atrophy and loss of contractile function. In part, this response is believed to be mediated by the transcription factor nuclear factor-kappa B (NF-κB). Both curcumin, a comp...

    Authors: Mehran Farid, Michael B Reid, Yi-Ping Li, Eric Gerken and William J Durham
    Citation: Nutrition & Metabolism 2005 2:20
  26. The Family Blood Pressure Program is an ongoing, NHLBI-sponsored, multi-center program to study the genetic determinants of high blood pressure. The goal of this particular study was to study patterns of metab...

    Authors: Aldi T Kraja, DC Rao, Alan B Weder, Thomas H Mosley, Stephen T Turner, Chao Agnes Hsiung, Thomas Quertermous, Richard Cooper, J David Curb and Michael A Province
    Citation: Nutrition & Metabolism 2005 2:17
  27. A low fat, high carbohydrate diet in combination with regular exercise is the traditional recommendation for treating diabetes. Compliance with these lifestyle modifications is less than satisfactory, however,...

    Authors: Surender K Arora and Samy I McFarlane
    Citation: Nutrition & Metabolism 2005 2:16
  28. Obesity is associated with insulin resistance that can often be improved by caloric restriction and weight reduction. Although many physiological changes accompanying insulin resistance and its treatment have ...

    Authors: R Michael Raab, John Bullen, Joanne Kelleher, Christos Mantzoros and Gregory Stephanopoulos
    Citation: Nutrition & Metabolism 2005 2:15
  29. Plasma total homocysteine (tHcy) is commonly elevated in persons with diabetes. This may be due to effects of insulin and/or glucose and/or metabolic control on the metabolism or plasma levels of tHcy. This st...

    Authors: Glen E Duncan, Sierra M Li and Xiao-Hua Zhou
    Citation: Nutrition & Metabolism 2005 2:13
  30. Energy and Zinc (Zn) deficiencies have been associated with nutritional related growth retardation as well as growth hormone (GH) resistance. In this study, the relationship between suboptimal energy and/or Zn...

    Authors: Russell Rising, Julio F Scaglia, Conrad Cole, Rozalia Tverskaya, Debora Duro and Fima Lifshitz
    Citation: Nutrition & Metabolism 2005 2:10
  31. Osteoporosis is a major public health problem with low bone mass affecting nearly half the women aged 50 years or older. Evidence from various studies has shown that higher body mass index (BMI) is a protectiv...

    Authors: Jonathan P Castro, Linda A Joseph, John J Shin, Surender K Arora, John Nicasio, Joshua Shatzkes, Irina Raklyar, Irina Erlikh, Vincent Pantone, Gul Bahtiyar, Leon Chandler, Lina Pabon, Sara Choudhry, Nilofar Ghadiri, Pramodini Gosukonda, Rangnath Muniyappa…
    Citation: Nutrition & Metabolism 2005 2:9
  32. Cholesterol ester transfer protein (CETP) plays a major role in regulating the levels of LDL- and HDL-cholesterol. We previously observed a fish-oil-induced elevation of low-density lipoprotein (LDL)-and very-...

    Authors: Pujitha P de Silva, Alka Agarwal-Mawal, Phillip J Davis and Sukhinder Kaur Cheema
    Citation: Nutrition & Metabolism 2005 2:8
  33. Although feeding deficits have been reported in snakes and lizards following vomeronasal system disruption, no deficit has been previously reported in a mammal. We tested gray short-tailed opossums with items ...

    Authors: Mimi Halpern, Yasmine Daniels and Ido Zuri
    Citation: Nutrition & Metabolism 2005 2:6

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