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  1. Previous reports regarding the predictive power of adiposity indices remain inconsistent, and longitudinal studies on this top are limited. The associations of hyperuricemia risk with changes in obesity status...

    Authors: Zonglei Zhou, Kunpeng Li, Xianzhi Li, Rongsheng Luan and Ruzhen Zhou

    Citation: Nutrition & Metabolism 2021 18:62

    Content type: Research

    Published on:

  2. Previous work in HEK-293 cells demonstrated the importance of amino acid-induced mTORC1 translocation to the lysosomal surface for stimulating mTORC1 kinase activity and protein synthesis. This study tested th...

    Authors: Michael S. Borack, Jared M. Dickinson, Christopher S. Fry, Paul T. Reidy, Melissa M. Markofski, Rachel R. Deer, Kristofer Jennings, Elena Volpi and Blake B. Rasmussen

    Citation: Nutrition & Metabolism 2021 18:61

    Content type: Research

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  3. The practical relevance of metabolic adaptation remains a controversial issue. To the best of our knowledge, no study has properly evaluated the role of metabolic adaptation in modulating weight loss outcomes....

    Authors: Catia Martins, Jessica Roekenes, Barbara A. Gower and Gary R. Hunter

    Citation: Nutrition & Metabolism 2021 18:60

    Content type: Research

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  4. To prospectively examine the associations of baseline serum uric acid (SUA) and SUA changes with incident metabolic syndrome (MetS) and update the evidence through a meta-analysis.

    Authors: Sen Chen, Nianwei Wu, Chuan Yu, Ying Xu, Chengfu Xu, Yuli Huang, Jian Zhao, Ningxiu Li and Xiong-Fei Pan

    Citation: Nutrition & Metabolism 2021 18:59

    Content type: Research

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  5. Feeding rhythm disruption contributes to the development of obesity. The receptors of glucagon-like peptide-1 (GLP-1) are distributed in the wide regions of the brain. Among these regions, GLP-1 receptors (GLP...

    Authors: Yuko Maejima, Shoko Yokota, Masaru Shimizu, Shoichiro Horita, Daisuke Kobayashi, Akihiro Hazama and Kenju Shimomura

    Citation: Nutrition & Metabolism 2021 18:58

    Content type: Research

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  6. Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders among women of reproductive age. This study was designed to investigate the effects of melatonin and/or magnesium supplementation ...

    Authors: Mohammad Alizadeh, Majid Karandish, Mohammad Asghari Jafarabadi, Lida Heidari, Roshan Nikbakht, Hossein Babaahmadi Rezaei and Reihaneh Mousavi

    Citation: Nutrition & Metabolism 2021 18:57

    Content type: Research

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  7. High-fat diet (HFD)-induced obesity causes immune cells to infiltrate adipose tissue, leading to chronic inflammation and metabolic syndrome. Brown adipose tissue (BAT) can dissipate the energy produced by lip...

    Authors: Pengyu Fu, Rongxin Zhu, Jie Jia, Yang Hu, Chengjun Wu, Pawel Cieszczyk, Hans-Christer Holmberg and Lijing Gong

    Citation: Nutrition & Metabolism 2021 18:56

    Content type: Research

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  8. The TM4 (UBAC2) protein, which contains 4 transmembrane domains and one ubiquitin binding domain, is mainly expressed in cell and nuclear membranes. The current research aimed to explore the role of TM4 in metabo...

    Authors: Lili Chen, Kuanping Ye, Xiaocheng Feng, Lianxi Li, Qin Li, Ying Huang, Xuanchun Wang, Rumei Li, Cheng Hu, Zhen Yang, Bin Lu, Yehong Yang, Jie Wen, Zhaoyun Zhang, Min He, Qinghua Wang…

    Citation: Nutrition & Metabolism 2021 18:54

    Content type: Research

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  9. Soybean oil is a very common edible oil in daily life. With the changes in the dietary composition, the intake of soybean oil increased. However, the effects of dietary intake of soybean oil on testosterone pr...

    Authors: Yu Su, Zhenhua Tian, Xiangyu Qi, Dandan Luo, Luna Liu, Shuang Liu, Dongmei Zheng, Fang Wei, Zhao He and Qingbo Guan

    Citation: Nutrition & Metabolism 2021 18:53

    Content type: Research

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  10. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Pariyarath Sangeetha Thondre, Helen Lightowler, Lis Ahlstrom and Andrew Gallagher

    Citation: Nutrition & Metabolism 2021 18:52

    Content type: Correction

    Published on:

    The original article was published in Nutrition & Metabolism 2021 18:41

  11. Whether vitamin D supplementation has any effect on body fat percentage, especially among elite athletes, remains unclear. The aim of this study was to evaluate the effect of vitamin D supplementation on serum...

    Authors: Itaru Kawashima, Takashi Tsukahara, Ryosuke Kawai, Takafumi Mizuno, Shinya Ishizuka, Hideki Hiraiwa and Shiro Imagama

    Citation: Nutrition & Metabolism 2021 18:51

    Content type: Research

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  12. Mitochondrial dysfunction has been implicated as a significant factor in the liver disease process. Blueberry juice and probiotics (BP) synergistically improve liver function in alcoholic fatty liver disease (...

    Authors: Houmin Fan, Yanyan Shen, Ya Ren, Qiuju Mou, Tao Lin, Lili Zhu and Tingting Ren

    Citation: Nutrition & Metabolism 2021 18:50

    Content type: Research

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  13. Tight junction proteins play crucial roles in maintaining the intestinal mucosal barrier. Although previous studies have shown that Notch signaling is closely related to tight junction proteins, the mechanism ...

    Authors: Fubin Qiu, Zehui Zhang, Linxue Yang, Rui Li and Ying Ma

    Citation: Nutrition & Metabolism 2021 18:49

    Content type: Research

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  14. Caloric restriction (CR) has become increasingly attractive in the treatment of type 2 diabetes mellitus (T2DM) because of the increasingly common high-calorie diet and sedentary lifestyle. This study aimed to...

    Authors: Li Zhang, Ying-juan Huang, Jia-pan Sun, Ting-ying Zhang, Tao-li Liu, Bin Ke, Xian-fang Shi, Hui Li, Geng-peng Zhang, Zhi-yu Ye, Jianguo Hu and Jian Qin

    Citation: Nutrition & Metabolism 2021 18:48

    Content type: Research

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  15. Application of mixed meal tolerance tests (MMTT) to measure beta-cell function in long-term studies is limited by modification of the commercial products occurring over time. This study assessed the intra-indi...

    Authors: Theresa Kössler, Pavel Bobrov, Klaus Strassburger, Oliver Kuss, Oana-Patricia Zaharia, Yanislava Karusheva, Clara Möser, Kálmán Bódis, Volker Burkart, Michael Roden and Julia Szendroedi

    Citation: Nutrition & Metabolism 2021 18:47

    Content type: Brief communication

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  16. Withania coagulans (Stocks) Dunal fruits are used in the therapeutics of several ailments due to possessing of potent phytoconstituents which is also used traditionally for curing the diabetes.

    Authors: Heera Ram, Pramod Kumar, Ashok Purohit, Priya Kashyap, Suresh Kumar, Shivani Kumar, Garima Singh, Abdulaziz A. Alqarawi, Abeer Hashem, Elsayed Fathi Abd-Allah, Al-Bandari Fahad Al-Arjani and Bhim Pratap Singh

    Citation: Nutrition & Metabolism 2021 18:43

    Content type: Research

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  17. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Amin Salehpour, Mehdi Hedayati, Farzad Shidfar, Asal Neshatbini Tehrani, Ali Asghar Farshad and Saeed Mohammadi

    Citation: Nutrition & Metabolism 2021 18:42

    Content type: Correction

    Published on:

    The original article was published in Nutrition & Metabolism 2021 18:29

  18. There are many benefits of maintaining healthy blood glucose levels, and studies have shown that lifestyle changes such as changes to diet can successfully restore normoglycaemia in participants with dysglycae...

    Authors: Pariyarath Sangeetha Thondre, Helen Lightowler, Lis Ahlstrom and Andrew Gallagher

    Citation: Nutrition & Metabolism 2021 18:41

    Content type: Research

    Published on:

    The Correction to this article has been published in Nutrition & Metabolism 2021 18:52

  19. To meet the needs of foetal growth and development, marked changes in lipid profiles occur during pregnancy. Abnormal lipid metabolism is often accompanied by adverse pregnancy outcomes, which seriously affect...

    Authors: Jiayu Lu, Ying Gong, Xinhong Wei, Zhenyu Yao, Rui Yang, Jinxing Xin, Ling Gao and Shanshan Shao

    Citation: Nutrition & Metabolism 2021 18:40

    Content type: Research

    Published on:

  20. Mechanism exploitation of energy homeostasis is urgently required because of the worldwide prevailing of obesity-related metabolic disorders in human being. Although it is well known that leptin plays a centra...

    Authors: Huimin Liu, Tianxin Du, Chen Li and Guoqing Yang

    Citation: Nutrition & Metabolism 2021 18:39

    Content type: Review

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  21. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Zhiliang Cai, Qiaoxuan Zhang, Ziqiang Xia, Songbai Zheng, Lilan Zeng, Liqiao Han, Jun Yan, Peifeng Ke, Junhua Zhuang, Xinzhong Wu and Xianzhang Huang

    Citation: Nutrition & Metabolism 2021 18:38

    Content type: Correction

    Published on:

    The original article was published in Nutrition & Metabolism 2020 17:8

  22. Hypercholesterolemia is a major risk factor for cardiovascular disease. It has been reported that pineapple contains healthy nutrients and phytochemicals associated with antioxidant and anti-inflammatory capac...

    Authors: Porrnthanate Seenak, Sarawut Kumphune, Wachirawadee Malakul, Ratanon Chotima and Nitirut Nernpermpisooth

    Citation: Nutrition & Metabolism 2021 18:36

    Content type: Research

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  23. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Wanzi Jiang, Shushu Huang, Shuai Ma, Yingyun Gong, Zhenzhen Fu, Li Zhou, Wen Hu, Guofang Mao, Zhimin Ma, Ling Yang, Guangfeng Tang, Xiaofang Sun, Ping Zhang, Jianling Bai, Lei Chen, Bimin Shi…

    Citation: Nutrition & Metabolism 2021 18:35

    Content type: Correction

    Published on:

    The original article was published in Nutrition & Metabolism 2021 18:17

  24. Leucine deprivation modulates the dietary amino acid composition, reducing the fat content and improving the glucose tolerance, thus protecting the organism against obesity. However, a complete deprivation of ...

    Authors: Ziheng Zhou, Hanrui Yin, Yajie Guo, Yuanyuan Fang, Feixiang Yuan, Shanghai Chen and Feifan Guo

    Citation: Nutrition & Metabolism 2021 18:34

    Content type: Research

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  25. Many chronic disease patients experience a concurrent loss of lean muscle mass. Skeletal muscle is a dynamic tissue maintained by continuous protein turnover and progenitor cell activity. Muscle stem cells, or...

    Authors: Josiane Joseph and Jason D. Doles

    Citation: Nutrition & Metabolism 2021 18:33

    Content type: Review

    Published on:

  26. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Golbarg Rahimi, Salime Heydari, Bahareh Rahimi, Navid Abedpoor, Iman Niktab, Zahra Safaeinejad, Maryam Peymani, Farzad Seyed Forootan, Zahra Derakhshan, Mohammad Hossein Nasr Esfahani and Kamran Ghaedi

    Citation: Nutrition & Metabolism 2021 18:32

    Content type: Correction

    Published on:

    The original article was published in Nutrition & Metabolism 2021 18:14

  27. Due to the lack of evidence, advice pertaining to glycemic load (GL) can be misleading. Does the excessive restriction of GL, mostly through an extreme reduction in carbohydrate intake, result in a relatively ...

    Authors: Fengyi He, Chaogang Chen, Feng Li, Yiqin Qi, Xiuhong Lin, Ping Liang, Meng Ren and Li Yan

    Citation: Nutrition & Metabolism 2021 18:31

    Content type: Research

    Published on:

  28. Neck circumference, a proxy for upper-body subcutaneous fat, is a unique and pathogenic fat depot that confers additional metabolic risk. The purpose of present study was to determine whether neck circumferenc...

    Authors: Jie Shi, Zixuan Wang, Weiwei Zhang, Yixin Niu, Ning Lin, Xiaoyong Li, Hongmei Zhang, Guang Ning, Jiangao Fan, Li Qin, Qing Su and Zhen Yang

    Citation: Nutrition & Metabolism 2021 18:30

    Content type: Research

    Published on:

  29. 1,25-dihydroxyvitamin D3 may regulate adipogenesis in adipocytes in-vitro, but little is known about possible molecular mechanisms related to the inhibitory effect of 1,25-dihydroxyvitamin D3 on adipogenesis i...

    Authors: Amin Salehpour, Mehdi Hedayati, Farzad Shidfar, Asal Neshatbini Tehrani, Ali Asghar Farshad and Saeed Mohammadi

    Citation: Nutrition & Metabolism 2021 18:29

    Content type: Research

    Published on:

    The Correction to this article has been published in Nutrition & Metabolism 2021 18:42

  30. Cardiovascular diseases (CVDs) are associated with an unhealthy lifestyle, including poor diet. Indices reflecting the overall quality of diets are more effective than single food or nutrient-based approaches ...

    Authors: Fatemeh Nouri, Masoumeh Sadeghi, Noushin Mohammadifard, Hamidreza Roohafza, Awat Feizi and Nizal Sarrafzadegan

    Citation: Nutrition & Metabolism 2021 18:28

    Content type: Research

    Published on:

  31. Cancer-associated cachexia is a multifactorial syndrome defined by progressive weight loss with ongoing loss of adipose tissue and skeletal muscle. Adipose loss occurs in the early stage of cachexia and is ass...

    Authors: Jun Han, Lei Shen, Zheng Zhan, Yuguo Liu, Chang Zhang, Ruochen Guo, Yangjun Luo, Zhiqin Xie, Ying Feng and Guohao Wu

    Citation: Nutrition & Metabolism 2021 18:27

    Content type: Research

    Published on:

  32. Nonalcoholic fatty liver disease (NAFLD) is the most prevalent liver disease and is characterized by excessive fat accumulation. Kaili Sour Soup, a food typical of Guizhou Province, is believed to have signifi...

    Authors: Shuo Cong, Zhengchao Li, Lei Yu, Yongmei Liu, Yaxin Hu, Ying Bi and Mingliang Cheng

    Citation: Nutrition & Metabolism 2021 18:26

    Content type: Research

    Published on:

  33. The link between total cholesterol (TC) and all-cause and specific mortality has not been elucidated. Herein, we aimed to evaluate the effect of TC levels on all-cause, cardiovascular disease (CVD), and cancer...

    Authors: Guo-dong He, Xiao-cong Liu, Lin Liu, Yu-ling Yu, Chao-lei Chen, Jia-yi Huang, Kenneth Lo, Yu-qing Huang and Ying-qing Feng

    Citation: Nutrition & Metabolism 2021 18:25

    Content type: Research

    Published on:

  34. The low carbohydrate, high fat ketogenic diet can be an effective anticonvulsant treatment in some pediatric patients with pharmacoresistant epilepsy. Its mechanism(s) of action, however, remain uncertain. Dir...

    Authors: Susan A. Masino, David N. Ruskin, Natalie R. Freedgood, Marie Lindefeldt and Maria Dahlin

    Citation: Nutrition & Metabolism 2021 18:23

    Content type: Research

    Published on:

  35. One of the most prevalent diseases worldwide without a fully-known mechanism is non-alcoholic fatty liver disease (NAFLD). Recently, long non-coding RNAs (lncRNAs) have emerged as significant regulatory molecu...

    Authors: Arezoo Gowhari Shabgah, Fatemeh Norouzi, Mahdiyeh Hedayati-Moghadam, Davood Soleimani, Naseh Pahlavani and Jamshid Gholizadeh Navashenaq

    Citation: Nutrition & Metabolism 2021 18:22

    Content type: Review

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  36. Body composition may explain partially why non-obese individuals still at the risk of developing non-alcoholic fatty liver disease (NAFLD). The ratio of fat mass to fat-free mass (FM/FFM) has been proposed to ...

    Authors: Huajie Dai, Jiali Xiang, Yanan Hou, Liping Xuan, Tiange Wang, Mian Li, Zhiyun Zhao, Yu Xu, Jieli Lu, Yuhong Chen, Weiqing Wang, Guang Ning, Yufang Bi and Min Xu

    Citation: Nutrition & Metabolism 2021 18:21

    Content type: Research

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  37. Patients with estrogen receptor negative (ER) breast cancer have poor prognosis due to high rates of metastasis. However, there is no effective treatment and drugs for ER breast cancer metastasis. Our purpose o...

    Authors: Yuelin Tong, Zhongwei Li, Yikuan Wu, Shenglong Zhu, Keke Lu and Zhao He

    Citation: Nutrition & Metabolism 2021 18:20

    Content type: Research

    Published on:

  38. More studies have shown that serum calcium has a crucial role in many types of cancers. However, few studies have determined the association between serum calcium levels and renal impairment (RI) and all-cause...

    Authors: Jun Cheng, Wen Zhang, Yi Zhao, Xiayu Li, Rong Lv, Heng Li and Jianghua Chen

    Citation: Nutrition & Metabolism 2021 18:19

    Content type: Research

    Published on:

  39. Diabetes was a major risk factor for numerous chronic diseases. However, the associations between daytime napping and diabetes in the existing literature is still inconsistent.

    Authors: Hao Wang, Lingli Chen, Dun Shen, Yuan Cao, Xiaoyi Zhang, Kaixu Xie, Chunmei Wang, Shuiqing Zhu, Yu Guo, Bragg Fiona, Min Yu, Zhengming Chen and Liming Li

    Citation: Nutrition & Metabolism 2021 18:18

    Content type: Research

    Published on:

  40. Obesity is a globally increasing health epidemic requiring early lifestyle intervention. Our main objective was to examine the effectiveness of companion-intensive multi-aspect weight management (CIMWM) in Chi...

    Authors: Wanzi Jiang, Shushu Huang, Shuai Ma, Yingyun Gong, Zhenzhen Fu, Li Zhou, Wen Hu, Guofang Mao, Zhimin Ma, Ling Yang, Guangfeng Tang, Xiaofang Sun, Ping Zhang, Jianling Bai, Lei Chen, Bimin Shi…

    Citation: Nutrition & Metabolism 2021 18:17

    Content type: Research

    Published on:

    The Correction to this article has been published in Nutrition & Metabolism 2021 18:35

  41. Since evidence regarding to low carbohydrate diet (LCD) and psychiatric disorders is little and controversial, this study aimed to assess relation between LCD score and psychological disorders including depres...

    Authors: Zohreh Sadat Sangsefidi, Amin Salehi-Abarghouei, Zahra Sadat Sangsefidi, Masoud Mirzaei and Mahdieh Hosseinzadeh

    Citation: Nutrition & Metabolism 2021 18:16

    Content type: Research

    Published on:

  42. Nutritional ergogenic aids are foods or nutrients that can improve physical performance. Among these foods with ergogenic properties, caffeine has shown that it can increase the fat catabolism, strength, and i...

    Authors: Kelvin Euton Oliveira Carmo, Diego Ignácio Valenzuela Pérez, Charles Nardelli Valido, Jymmys Lopes dos Santos, Bianca Miarka, Raquel Simões Mendes-Netto, Marina Macedo Rodrigues Leite, Naiara Ribeiro Antoniêtto, Esteban Ariel Aedo-Muñoz and Ciro José Brito

    Citation: Nutrition & Metabolism 2021 18:15

    Content type: Research

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  43. Lipotoxicity-induced cell death plays a detrimental role in the pathogenesis of metabolic diseases. Ferulic acid, widespread in plant-based food, is a radical scavenger with multiple bioactivities. However, th...

    Authors: Tiantian Xu, Qing Song, Li Zhou, Wenwen Yang, Xiangyao Wu, Qianyu Qian, Hui Chai, Qiang Han, Hongzhi Pan, Xiaobing Dou and Songtao Li

    Citation: Nutrition & Metabolism 2021 18:13

    Content type: Research

    Published on:

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