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  1. Although type 2 diabetes mellitus (T2DM) is primarily characterized by sustained high levels of circulating glucose, other factors, such as obesity, chronic inflammation, fatty liver, and islet dysfunction sig...

    Authors: Yoo Kim, Michael Rouse, Isabel González-Mariscal, Josephine M. Egan and Jennifer F. O’Connell

    Citation: Nutrition & Metabolism 2019 16:48

    Content type: Research

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  2. Flavonoids are a class of plant and fungus secondary metabolites and are the most common group of polyphenolic compounds in the human diet. In recent studies, flavonoids have been shown to induce browning of w...

    Authors: Xuejun Zhang, Xin Li, Huang Fang, Fengjin Guo, Feng Li, Anmin Chen and Shilong Huang

    Citation: Nutrition & Metabolism 2019 16:47

    Content type: Review

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  3. There is a growing interest in the pathopysiological consequences of postprandial hyperglycemia. It is well known that in diabetic patients 2 h plasma glucose is a better risk predictor for coronary heart dise...

    Authors: María González-Rodríguez, Marcos Pazos-Couselo, José M. García-López, Santiago Rodríguez-Segade, Javier Rodríguez-García, Carmen Túñez-Bastida and Francisco Gude

    Citation: Nutrition & Metabolism 2019 16:46

    Content type: Research

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  4. Trehalose is well known as a functional disaccharide with anti-metabolic activities such as suppression of adipocyte hypertrophy in mice and alleviation of impaired glucose tolerance in humans. Recently, a new...

    Authors: Chikako Arai, Norie Arai, Shigeyuki Arai, Chiyo Yoshizane, Satomi Miyata, Akiko Mizote, Aki Suyama, Shin Endo, Toshio Ariyasu, Hitoshi Mitsuzumi and Shimpei Ushio

    Citation: Nutrition & Metabolism 2019 16:45

    Content type: Research

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  5. Visceral adiposity has been reported to play a key role in hypertension compared with other measurements of regional or general obesity. The aim of current study was to evaluate the relationship between viscer...

    Authors: Xiaohui Guo, Yifan Xu, Hairong He, Hao Cai, Jianfen Zhang, Yibin Li, Xinyu Yan, Man Zhang, Na Zhang, Rolando L. Maddela and Guansheng Ma

    Citation: Nutrition & Metabolism 2019 16:44

    Content type: Research

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  6. The chemokine receptor CCR7, expressed on various immune cells, is associated with cell migration and lympho-node homing. Mice lacking Ccr7 are protected from diet-induced obesity and subsequent insulin resist...

    Authors: Tomomi Sano, Taiki Sanada, Yusuke Sotomaru, Takanori Shinjo, Misaki Iwashita, Akiko Yamashita, Takao Fukuda, Terukazu Sanui, Tomoichiro Asano, Takashi Kanematsu and Fusanori Nishimura

    Citation: Nutrition & Metabolism 2019 16:43

    Content type: Research

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  7. Endothelial oxidative injury is a key event in the pathogenesis of atherosclerosis (AS). Resveratrol (RSV) attenuates the oxidative injury in human umbilical vein endothelial cells (HUVECs). Autophagy is criti...

    Authors: Xi Zhou, Jining Yang, Min Zhou, Yu Zhang, Yang Liu, Pengfei Hou, Xianglong Zeng, Long Yi and Mantian Mi

    Citation: Nutrition & Metabolism 2019 16:42

    Content type: Research

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  8. Apolipoprotein A-IV (ApoA-IV) exists in relatively high levels in the circulation systems of animals, but its roles are not fully elucidated. It is known that the Apoa4 gene resides in the cluster Apoa1/Apoc3/Apo...

    Authors: Zhenguo Wang, Lu Wang, Zhuzhen Zhang, Li Feng, Xue Song and Jiarui Wu

    Citation: Nutrition & Metabolism 2019 16:41

    Content type: Research

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  9. As reported previously by our group, medium-chain triglycerides can ameliorate atherosclerosis. Given that TLR4 is closely related to atherosclerosis, we hypothesized herein that caprylic acid (C8:0) would sup...

    Authors: Xinsheng Zhang, Changyong Xue, Qing Xu, Yong Zhang, Huizi Li, Feng Li, Yinghua Liu and Changjiang Guo

    Citation: Nutrition & Metabolism 2019 16:40

    Content type: Research

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  10. Long non-coding RNAs (lncRNAs) are involved in numerous physiological functions. Yet, their mechanisms in coronary artery disease (CAD) are not well understood.

    Authors: Liu Miao, Rui-Xing Yin, Qing-Hui Zhang, Xi-Jiang Hu, Feng Huang, Wu-Xian Chen, Xiao-Li Cao and Jin-Zhen Wu

    Citation: Nutrition & Metabolism 2019 16:39

    Content type: Research

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  11. The incidence of metabolic syndrome linked to dyslipidemia and insulin resistance has increased; thus, studies must be conducted to elucidate this phenomenon. The present study aimed to investigate the protect...

    Authors: Oeuk Jeong and Hyun-Sook Kim

    Citation: Nutrition & Metabolism 2019 16:38

    Content type: Research

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  12. Proliferative diabetic retinopathy (PDR), a sight-threatening retinopathy, is the leading cause of irreversible blindness in adults. Despite strict control of systemic risk factors, a fraction of patients with...

    Authors: Xiao-Rong Zhu, Fang-yuan Yang, Jing Lu, Hui-rong Zhang, Ran Sun, Jian-Bo Zhou and Jin-Kui Yang

    Citation: Nutrition & Metabolism 2019 16:37

    Content type: Research

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  13. High levels circulating saturated fatty acids are associated with diabetes, obesity and hyperlipidemia. In heart, the accumulation of saturated fatty acids has been determined to play a role in the development...

    Authors: Kuen-Ming Wu, Yuan-Man Hsu, Mei-Chin Ying, Fuu-Jen Tsai, Chang-Hai Tsai, Jing-Gung Chung, Jai-Sing Yang, Chih-Hsin Tang, Li-Yi Cheng, Po-Hua Su, Vijaya Padma Viswanadha, Wei-Wen Kuo and Chih-Yang Huang

    Citation: Nutrition & Metabolism 2019 16:36

    Content type: Research

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  15. Blueberry is rich in bioactive substances and possesses powerful antioxidant potential, which can protect against oxidant-induced and inflammatory cell damage and cytotoxicity. The aim of this study was to det...

    Authors: Weixiang Liu, Yiping Mao, Jacob Schoenborn, Zhihong Wang, Guiliang Tang and Xiaoqing Tang

    Citation: Nutrition & Metabolism 2019 16:34

    Content type: Research

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  16. Cutaneous malignant melanoma is a heterogeneous disease, being the consequence of specific genetic alterations along several molecular pathways. Despite the increased knowledge about the biology and pathogenes...

    Authors: Maria Neve Ombra, Panagiotis Paliogiannis, Luigia Stefania Stucci, Maria Colombino, Milena Casula, Maria Cristina Sini, Antonella Manca, Grazia Palomba, Ignazio Stanganelli, Mario Mandalà, Sara Gandini, Amelia Lissia, Valentina Doneddu, Antonio Cossu and Giuseppe Palmieri

    Citation: Nutrition & Metabolism 2019 16:33

    Content type: Review

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  17. Adipogenesis, the process of preadipocyte differentiation to mature adipocytes accompanied by accumulation of intracytoplasmic lipid droplets, is regulated by various genetic and environmental factors, and clo...

    Authors: Yusuke Ando, Fumiaki Sato, Hazuki Fukunaga, Yusuke Iwasaki, Yoshihiko Chiba, Masahiko Tebakari, Yuki Daigo, Junichi Kawashima and Junzo Kamei

    Citation: Nutrition & Metabolism 2019 16:32

    Content type: Research

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  18. Obesity increases the risk of metabolic dysfunction such as dyslipidemia, hypertension, and fatty liver. Physcion (PY) is an anthraquinone that reportedly has anti-inflammatory and anti-bacterial properties. H...

    Authors: Seon-Jeong Lee, Su-Jung Cho, Eun-Young Kwon and Myung-Sook Choi

    Citation: Nutrition & Metabolism 2019 16:31

    Content type: Research

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  19. Several biomarkers are used to measure iron deficiency (ID) during pregnancy, but the prevalence of ID and its association with adverse birth outcomes shows inconsistent results. The aim of this study was to e...

    Authors: Xiaosong Yuan, Huiwen Hu, Ming Zhang, Wei Long, Jianbing Liu, Jian Jiang and Bin Yu

    Citation: Nutrition & Metabolism 2019 16:30

    Content type: Research

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  20. It is not clear whether the frequently reported phenomenon of exercise-induced anorexia is exacerbated or blunted in warm or cold environments. Therefore, this study investigated the effects of exercise in thr...

    Authors: Iva Mandic, Mavra Ahmed, Shawn Rhind, Len Goodman, Mary L’Abbe and Ira Jacobs

    Citation: Nutrition & Metabolism 2019 16:29

    Content type: Research

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  21. This study aimed to assess the potential effects of long-term intake of caffeine and habitual consumption of coffee and tea on the occurrence of cardio-renal events among an Iranian population with low coffee ...

    Authors: Zahra Gaeini, Zahra Bahadoran, Parvin Mirmiran and Fereidoun Azizi

    Citation: Nutrition & Metabolism 2019 16:28

    Content type: Research

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  22. Reprogramming of fast-to-slow myofiber switch can improve endurance capacity and alleviate fatigue. Accumulating evidence suggests that a muscle-specific microRNA, miR-499 plays a crucial role in myofiber type...

    Authors: Luting Wu, Li Ran, Hedong Lang, Min Zhou, Li Yu, Long Yi, Jundong Zhu, Lei Liu and Mantian Mi

    Citation: Nutrition & Metabolism 2019 16:27

    Content type: Research

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  23. Prolonged over-consumption of a high-fat diet (HFD) commonly leads to obesity and insulin resistance. However, even 3 days of HFD consumption has been linked to inflammation within the key homeostatic brain re...

    Authors: Fiona H. McLean, Fiona M. Campbell, Rosamund F. Langston, Domenico Sergi, Cibell Resch, Christine Grant, Amanda C. Morris, Claus D. Mayer and Lynda M. Williams

    Citation: Nutrition & Metabolism 2019 16:26

    Content type: Research

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  24. Myricetin, a major flavonoid found in several foods including berries, grapes and wine, exhibited strong antioxidant potency, yet the effect on atherosclerosis is not fully understood. In this study, we examin...

    Authors: Zhe Meng, Mengyu Wang, Junhui Xing, Yuzhou Liu and Haiyu Li

    Citation: Nutrition & Metabolism 2019 16:25

    Content type: Research

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  25. Consumption of diet high in soy products is suggested to contribute to lower prostate cancer incidence in Asian men. But little has been known about the influences of dietary patterns on gut microbiota and mic...

    Authors: Yufei Liu, Xiaobo Wu and Haowen Jiang

    Citation: Nutrition & Metabolism 2019 16:24

    Content type: Research

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  26. The process of atherosclerosis begins early in childhood and usually remains asymptomatic until later in life. Carotid intima-media thickness (cIMT) as a marker of subclinical atherosclerosis could identify ea...

    Authors: Maryam Aghayan, Golaleh Asghari, Emad Yuzbashian, Pooneh Dehghan, Hossein Khadem Haghighian, Parvin Mirmiran and Maryam Javadi

    Citation: Nutrition & Metabolism 2019 16:23

    Content type: Research

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  27. Chronic inflammation and metabolic dysregulation may eventually cause tissue damage in obesity-related diseases such as type 2 diabetes. The effects of SIRT1 on integration of metabolism and inflammation may p...

    Authors: Hung-Wen Liu, Hao-Han Kao and Chi-Hang Wu

    Citation: Nutrition & Metabolism 2019 16:22

    Content type: Research

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  28. Differences in total body and regional adiposity according to sex are observed from an early age, but these differences become more evident after puberty due to hormonal changes. We aimed to assess the evoluti...

    Authors: Silvana Paiva Orlandi, Leonardo Pozza Santos, Ana Maria Baptista Menezes, Fernando C. Wehrmeister, Helen Gonçalves and Maria Cecília Formoso Assunção

    Citation: Nutrition & Metabolism 2019 16:21

    Content type: Research

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  29. Maternal undernutrition programs fetal energy homeostasis and increases the risk of metabolic disorders later in life. This study aimed to identify the signs of hepatic metabolic programming in utero and durin...

    Authors: Xiaoling Zhou, Hong Yang, Qiongxian Yan, Ao Ren, Zhiwei Kong, Shaoxun Tang, Xuefeng Han, Zhiliang Tan and Abdelfattah Z. M. Salem

    Citation: Nutrition & Metabolism 2019 16:20

    Content type: Research

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  30. Maternal riboflavin deficiency (RD) induces embryonic death in poultry. The underlying mechanisms, however, remain to be established and an overview of molecular alterations at the protein level is still lacki...

    Authors: Jing Tang, Jian Hu, Ming Xue, Zhanbao Guo, Ming Xie, Bo Zhang, Zhengkui Zhou, Wei Huang and Shuisheng Hou

    Citation: Nutrition & Metabolism 2019 16:19

    Content type: Research

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  31. Gut derived toxins such as p-cresol, p-cresyl sulfate (pCS) and indoxyl sulfate (IS), which belong to protein-bound uremic toxins that promote development of fibrosis inflammatory state associated with chronic...

    Authors: Hamid Tayebi Khosroshahi, Behzad Abedi, Morteza Ghojazadeh, Azam Samadi and Abolghasem Jouyban

    Citation: Nutrition & Metabolism 2019 16:18

    Content type: Research

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  32. To investigate the influences of exercise on the levels of chemerin and its receptor chemokine-like receptor (CMKLR1) in the peripheral metabolic organs of obesity and diabetes rats, and whether the mechanism ...

    Authors: Xiaojing Lin, Yanan Yang, Jing Qu and Xiaohui Wang

    Citation: Nutrition & Metabolism 2019 16:17

    Content type: Research

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  34. Epidemiological and experimental studies have extensively indicated that chronic subclinical systemic inflammation (CSSI) and oxidative stress are risk factors for several chronic diseases, including cancer, a...

    Authors: Yazan Ranneh, Abdah Md Akim, Hasiah Ab Hamid, Huzwah Khazaai, Abdulmannan Fadel and Ayman M. Mahmoud

    Citation: Nutrition & Metabolism 2019 16:15

    Content type: Research

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  35. Adiponectin exerts several beneficial cardiovascular effects, however their specific molecular mechanisms require additional understanding. This study investigated the mechanisms of adiponectin action in the h...

    Authors: Amy Botta, Ying Liu, Sivaporn Wannaiampikul, Rungsunn Tungtrongchitr, Keith Dadson, Tae-Sik Park and Gary Sweeney

    Citation: Nutrition & Metabolism 2019 16:14

    Content type: Research

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  36. Iron is a critical component of metabolic homeostasis, but consumption of dietary iron has increased dramatically in the last 30 years, corresponding with the rise of metabolic disease. While the link between ...

    Authors: Mario A. Miranda, Celine L. St Pierre, Juan F. Macias-Velasco, Huyen Anh Nguyen, Heather Schmidt, Lucian T. Agnello, Jessica P. Wayhart and Heather A. Lawson

    Citation: Nutrition & Metabolism 2019 16:13

    Content type: Research

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  37. Oil tea is a type of traditional tea beverage used for treating various ailments in minority population in Guangxi, China. Our previous study showed oil tea improved glucose and lipid levels in type 2 diabetic...

    Authors: Qiantu Hu, Huafeng Chen, Yanli Zuo, Qin He, Xuan He, Steve Simpson Jr, Wei Huang, Hui Yang, Haiying Zhang and Rui Lin

    Citation: Nutrition & Metabolism 2019 16:12

    Content type: Research

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  38. Catch-up growth in adult (CUGA) is characterized by visceral fat accumulation, ectopic lipid deposition and insulin resistance (IR). Here, we investigated the determinants of these pathophysiological consequen...

    Authors: Yan Li, Shan Yu, Lulu Chen, Xiang Hu, Juan Zheng and Xiuling Deng

    Citation: Nutrition & Metabolism 2019 16:11

    Content type: Research

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  40. Oxidative stress-induced damage in endothelial cells is a crucial initiator of atherosclerosis (AS), which is highly related to excessive reactive oxygen species (ROS) and mitochondrial dynamics. Resveratrol (...

    Authors: Jining Yang, Xi Zhou, Xianglong Zeng, Ou Hu, Long Yi and Mantian Mi

    Citation: Nutrition & Metabolism 2019 16:9

    Content type: Research

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  41. Since lifestyle changes are main therapies for non-alcoholic fatty liver disease (NAFLD), changing dietary components (nutritional or bioactive) may play a parallel important role. Few studies have assessed th...

    Authors: Seyed Ali Jazayeri-Tehrani, Seyed Mahdi Rezayat, Siavash Mansouri, Mostafa Qorbani, Seyed Moayed Alavian, Milad Daneshi-Maskooni and Mohammad-Javad Hosseinzadeh-Attar

    Citation: Nutrition & Metabolism 2019 16:8

    Content type: Research

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  42. Small dense LDL cholesterol (sdLDL-c) has been established to be highly associated with metabolic disorder. However, the relationship between circulating sdLDL-c and the presence of metabolic syndrome (MetS) h...

    Authors: Jiahua Fan, Yangqing Liu, Songping Yin, Nixuan Chen, Xinxiu Bai, Qiuyi Ke, Jia Shen and Min Xia

    Citation: Nutrition & Metabolism 2019 16:7

    Content type: Research

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  43. Obesity has become a public health concern worldwide because it is linked to numerous metabolic disorders, such as hyperlipidemia, hypertension and cardiovascular disease. Therefore, there is an urgent need to...

    Authors: Licong Yang, Yan Zhao, Yongfang Pan, Dongming Li and Guodong Zheng

    Citation: Nutrition & Metabolism 2019 16:6

    Content type: Research

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  44. The GC haplotype of the vitamin D binding protein (encoded by the GC gene) might be a risk factor to the vitamin D (VD) nutritional status for many populations, while evidences from the Chinese Han population are...

    Authors: Ji-Chang Zhou, Yumei Zhu, Chunmei Gong, Xiongshun Liang, Xiaoying Zhou, Yuanfei Xu, Deliang Lyu, Junluan Mo, Jian Xu, Jinping Song, Xiaoling Che, Shiqiang Sun, Changhua Huang and Xiao-Li Liu

    Citation: Nutrition & Metabolism 2019 16:5

    Content type: Research

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  45. Osteoporosis is one of the world’s major medical burdens in the twenty-first century. Pharmaceutical intervention currently focusses on decelerating bone loss, but phytochemicals such as baicalein, which is a ...

    Authors: Dominik Saul, Marie Weber, Marc Hendrik Zimmermann, Robyn Laura Kosinsky, Daniel Bernd Hoffmann, Björn Menger, Stefan Taudien, Wolfgang Lehmann, Marina Komrakova and Stephan Sehmisch

    Citation: Nutrition & Metabolism 2019 16:4

    Content type: Research

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  46. Although retinol binding protein 4 (RBP4) has been implicated in insulin resistance in experimental studies, the association between RBP4 and risk of type 2 diabetes remains unclear. We assessed this associati...

    Authors: Yeli Wang, Liang Sun, Xu Lin, Jian-Min Yuan, Woon-Puay Koh and An Pan

    Citation: Nutrition & Metabolism 2019 16:3

    Content type: Research

    Published on:

  47. Effective evaluation or prediction of therapy response could be helpful for treatment of chronic kidney disease (CKD), which may rely on accurate biomarkers. Acylcarnitines are involved with lipid metabolism a...

    Authors: Fang-Ying Xia, Li Zhu, Chao Xu, Qing-Qing Wu, Wan-Jia Chen, Rong Zeng and Yue-Yi Deng

    Citation: Nutrition & Metabolism 2019 16:2

    Content type: Research

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  48. Increased consumption of linoleic acid (LA, omega-6) in Western diets coupled with the pro-inflammatory and adipogenic properties of its derivatives has led to suggestions that fetal exposure to this dietary p...

    Authors: Sally A. V. Draycott, Ge Liu, Zoe C. Daniel, Matthew J. Elmes, Beverly S. Muhlhausler and Simon C. Langley-Evans

    Citation: Nutrition & Metabolism 2019 16:1

    Content type: Research

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  49. Higher dietary intake of fibers and coffee, but lower red meat intake is associated with reduced risk for type 2 diabetes in epidemiological studies. We hypothesized that a calorie-restricted diet, which is hi...

    Authors: Yanislava Karusheva, Lejla Kunstein, Alessandra Bierwagen, Bettina Nowotny, Stefan Kabisch, Jan B. Groener, Ann Kristin Fleitmann, Christian Herder, Giovanni Pacini, Klaus Strassburger, Hans-Ulrich Häring, Peter P. Nawroth, Andreas F. H. Pfeiffer, Volker Burkart, Karsten Müssig, Michael Roden…

    Citation: Nutrition & Metabolism 2018 15:90

    Content type: Research

    Published on:

  50. In a previous study, we showed that consumption of diets enriched in saturated fatty acids causes changes in alternative splicing of pre-mRNAs encoding a number of proteins in rat skeletal muscle, including th...

    Authors: Adam J. Black, Rudolf J. Schilder and Scot R. Kimball

    Citation: Nutrition & Metabolism 2018 15:87

    Content type: Research

    Published on:

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