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  1. Recent studies suggest potential benefits of applying L-carnitine in the treatment of cancer cachexia, but the precise mechanisms underlying these benefits remain unknown. This study was conducted to determine...

    Authors: Changpeng Wu, Mingxing Zhu, Zongliang Lu, Yaowen Zhang, Long Li, Na Li, Liangyu Yin, He Wang, Wei Song and Hongxia Xu
    Citation: Nutrition & Metabolism 2021 18:98
  2. Early postnatal overfeeding could result in metabolic imprinting that decreases energy expenditure following white adipose tissue (WAT) gain throughout life. This research investigated whether curcumin (CUR) s...

    Authors: Xiaolei Zhu, Susu Du, Qinhui Yan, Cuiting Min, Nan Zhou, Wei Zhou and Xiaonan Li
    Citation: Nutrition & Metabolism 2021 18:97
  3. The association between dietary fats and the risk of cardiovascular disease (CVD) is under debate. We aimed to determine the potential effects of dietary saturated fats (SFA), mono-unsaturated (MUFA) and poly-...

    Authors: Zahra Gaeini, Parvin Mirmiran, Zahra Bahadoran, Maryam Aghayan and Fereidoun Azizi
    Citation: Nutrition & Metabolism 2021 18:96
  4. We prospectively examined the association between serum uric acid (SUA) levels and chronic kidney disease (CKD) in China and updated the evidence through a comprehensive meta-analysis of prospective studies wo...

    Authors: Nianwei Wu, Jing Xia, Sen Chen, Chuan Yu, Ying Xu, Chengfu Xu, Tong Yan, Ningxiu Li, Yanjun Liu and Xiong-Fei Pan
    Citation: Nutrition & Metabolism 2021 18:94
  5. In the last few years, the effects of bioactive food components have received much attention because of their beneficial effects including decreasing inflammation, scavenging free radicals, and regulating cell...

    Authors: Nasim Abedimanesh, Somayyeh Asghari, Kosar Mohammadnejad, Zahra Daneshvar, Soudeh Rahmani, Samaneh Shokoohi, Amir Hasan Farzaneh, Seyed Hojjat Hosseini, Iraj Jafari Anarkooli, Maryam Noubarani, Sina Andalib, Mohammad Reza Eskandari and Behrooz Motlagh
    Citation: Nutrition & Metabolism 2021 18:92
  6. Flaxseed is widely used as a functional food for its rich sources of linolenic acid, lignans and dietary fibers in the world. This systematic review and dose–response meta-analysis on randomized controlled tri...

    Authors: Chao Yang, Hui Xia, Min Wan, Yifei Lu, Dengfeng Xu, Xian Yang, Ligang Yang and Guiju Sun
    Citation: Nutrition & Metabolism 2021 18:91
  7. Limited information is available on arterial stiffness risk among hypertensive patients with metabolically abnormal but normal weight. Visceral adiposity index (VAI) is a novel indicator for visceral fat mass ...

    Authors: Junpei Li, Jian Zhu, Ziheng Tan, Yun Yu, Linfei Luo, Wei Zhou, Linjuan Zhu, Tao Wang, Tianyu Cao, Lishun Liu, Huihui Bao, Xiao Huang and Xiaoshu Cheng
    Citation: Nutrition & Metabolism 2021 18:90
  8. Time-restricted feeding is an emerging dietary intervention that is becoming increasingly popular. There are, however, no randomised clinical trials of time-restricted feeding in overweight patients with type ...

    Authors: Tingting Che, Cheng Yan, Dingyuan Tian, Xin Zhang, Xuejun Liu and Zhongming Wu
    Citation: Nutrition & Metabolism 2021 18:88
  9. This study assessed the performance of visceral adiposity index and body shape index in predicting diabetes mellitus (DM) risk and compared their predictive ability to that of body mass index and waist circumf...

    Authors: Meng-Ting Tsou, Yu-Chen Chang, Ching-Ping Hsu, Yang-Che Kuo, Chun-Ho Yun, Wei-Hsin Huang, Kuang-Chun Hu, Chia-Yuan Liu, Ying-Ju Chen, Kuo-Tzu Sung, Chuan-Chuan Liu, Chung-Lieh Hung, Jen-Yuan Kuo, Tung-Ying Chen, Ta-Chuan Hung and Hung-I. Yeh
    Citation: Nutrition & Metabolism 2021 18:87
  10. Precocious puberty is frequently associated with obesity, which will lead to long-term effects, especially on growth and reproduction. However, the effect of precocious puberty on children's neurodevelopment i...

    Authors: Tingbei Bo, Jing Wen, Wenting Gao, Liqiu Tang, Min Liu and Dehua Wang
    Citation: Nutrition & Metabolism 2021 18:86
  11. Androgen receptor (AR) exerts important roles in exercise-induced alterations of muscle mass, in which the proliferation and differentiation of satellite cells or myoblasts are crucial. Our previous study in C...

    Authors: Shaoting Fu, Xiaojing Lin, Lijun Yin and Xiaohui Wang
    Citation: Nutrition & Metabolism 2021 18:85
  12. Increased oxidative/dicarbonyl stress and chronic inflammation are considered key pathophysiological mediators in the progression of complications in obesity and type 2 diabetes (T2D). Lifestyle and diet compo...

    Authors: Hana Malinska, Marta Klementová, Michaela Kudlackova, Jiri Veleba, Eva Hoskova, Olena Oliyarnyk, Irena Markova, Lenka Thieme, Martin Hill, Terezie Pelikanova and Hana Kahleova
    Citation: Nutrition & Metabolism 2021 18:84
  13. Oxidative stress in hepatocytes was important pathogenesis of nonalcoholic steatohepatitis (NASH). Autophagy was a cellular process that can remove damaged organelles under oxidative stress, and thus presented...

    Authors: Li Huang, Xianglong Zeng, Bo Li, Cong Wang, Min Zhou, Hedong Lang, Long Yi and Mantian Mi
    Citation: Nutrition & Metabolism 2021 18:83
  14. As a newly proposed diagnosis, data on the prevalence of metabolic dysfunction-associated fatty liver disease (MAFLD) is rare. We aimed to assess the prevalence and risk factors of MAFLD using new definition i...

    Authors: Jiahua Fan, Shiyun Luo, Yongxin Ye, Jingmeng Ju, Zhuoyu Zhang, Ludi Liu, Jialu Yang and Min Xia
    Citation: Nutrition & Metabolism 2021 18:82
  15. Sanziguben polysaccharides (SZP) are large amounts of classical Chinese medicines from Sanziguben (SZGB). Moreover, SZGB is a widely applied compound prescription for diabetic nephropathy (DN) treatment, but t...

    Authors: Kang Zhou, Jianing Zhang, Chang Liu, Lijuan Ou, Fan Wang, Yang Yu, Yumei Wang and Shasha Bai
    Citation: Nutrition & Metabolism 2021 18:81
  16. This study aimed to examine the effect of yoga training combined with vitamin D supplementation on the expression of survival-related genes in leukocytes and psycho-physical status in breast cancer survivors.

    Authors: Vahid Khedmati Zare, Maedeh Javadi, Sadegh Amani-shalamzari and Mojtaba Kaviani
    Citation: Nutrition & Metabolism 2021 18:80
  17. Gestational diabetes mellitus (GDM), one of the most common pregnancy complications, can lead to morbidity and mortality in both the mother and the infant. Metabolomics has provided new insights into the patho...

    Authors: Wenqian Lu, Mingjuan Luo, Xiangnan Fang, Rong Zhang, Shanshan Li, Mengyang Tang, Xiangtian Yu and Cheng Hu
    Citation: Nutrition & Metabolism 2021 18:79
  18. Hypertension increases the likelihood of cardiovascular diseases (CVDs). Cytochrome P450 1A2 (CYP1A2) single nucleotide polymorphism (SNP) is related to caffeine metabolism and the risk of CVD among coffee dri...

    Authors: Chien-Chou Hou, Disline Manli Tantoh, Chuan-Chao Lin, Pei-Hsin Chen, Hao-Jan Yang and Yung-Po Liaw
    Citation: Nutrition & Metabolism 2021 18:78
  19. Obesity is associated with many comorbidities including inflammatory bowel disease (IBD). We investigated prophylactic effects of an herbal extract (HE) on the DSS-induced colitis mice challenged with high AGE...

    Authors: Fatemeh Azizian-Farsani, Marcin Osuchowski, Navid Abedpoor, Farzad Seyed Forootan, Maryam Derakhshan, Mohammad Hossein Nasr-Esfahani, Mohammad Hasan Sheikhha and Kamran Ghaedi
    Citation: Nutrition & Metabolism 2021 18:77
  20. Data from the 2010–2012 Chinese National Nutrition and Health Survey showed that the vast majority of postmenopausal women in China had dual deficiencies in calcium and estrogen.

    Authors: Hongmei Mao, Wenjun Wang, Lili Shi, Chen Chen, Chao Han, Jinpeng Zhao, Qin Zhuo, Shi Shen, Yan Li and Junsheng Huo
    Citation: Nutrition & Metabolism 2021 18:76
  21. Insulin resistance is associated with prediabetes and further progression to type 2 diabetes mellitus (T2DM). This study aims to investigate novel hepatic lncRNAs associated with key genes in insulin resistanc...

    Authors: Fatemeh Kazeminasab, Sayed Mohammad Marandi, Maryam Baharlooie, Mohammad Hossein Nasr-Esfahani and Kamran Ghaedi
    Citation: Nutrition & Metabolism 2021 18:75
  22. It was evidenced that saturated fatty acids (FAs) have a detrimental effect on pancreatic β-cells function and survival, leading to endoplasmic reticulum (ER) calcium release, ER stress, and apoptosis. In the ...

    Authors: Jan Šrámek, Vlasta Němcová and Jan Kovář
    Citation: Nutrition & Metabolism 2021 18:74
  23. Despite the worldwide burden of diverticular disease, the connections between diverticular disease and dietary habits remain poorly understood, particularly in an asymptomatic representative sample. We investi...

    Authors: Esther Askani, Susanne Rospleszcz, Theresa Rothenbacher, Nina Wawro, Helmut Messmann, Carlo N. De Cecco, Ricarda von Krüchten, Charlotte Kulka, Lena S. Kiefer, Wolfgang Rathmann, Annette Peters, Christopher L. Schlett, Fabian Bamberg, Jakob Linseisen and Corinna Storz
    Citation: Nutrition & Metabolism 2021 18:73
  24. Cardiac hypertrophy is an independent risk factor of many cardiovascular diseases. Studies have demonstrated that microRNA-126 (miR-126) was involved in angiogenesis during physiological and pathological proce...

    Authors: Haiyu Li, Xiaoxu Tian, Yongjuan Ruan, Junhui Xing and Zhe Meng
    Citation: Nutrition & Metabolism 2021 18:71
  25. Hypertension is a known risk factor for multiple chronic diseases. Existing literature on the association between frequency of spicy food consumption and hypertension shows mixed findings.

    Authors: Hao Wang, Lingli Chen, Dun Shen, Yuan Cao, Xiaoyi Zhang, Kaixu Xie, Chunmei Wang, Shuiqing Zhu, Pei Pei, Yu Guo, Fiona Bragg, Min Yu, Zhengming Chen and Liming Li
    Citation: Nutrition & Metabolism 2021 18:70
  26. The incidence of obesity is increasing worldwide, and it is a risk factor for diabetes, dyslipidemia, and nonalcoholic fatty liver disease. Our previous study had demonstrated that high-fat diet induced increa...

    Authors: Hongying Cai, Zhiguo Wen, Kun Meng and Peilong Yang
    Citation: Nutrition & Metabolism 2021 18:69
  27. Metabolic syndrome (MetS) is significantly associated with the risk of cardiovascular disease and its prevalence is showing a trend of getting younger. Previous studies on the relationship between elements and...

    Authors: Huidi Zhang, Qingqing Man, Pengkun Song, Siran Li, Xiaobing Liu, Lijuan Wang, Yuqian Li, Yichun Hu and Lichen Yang
    Citation: Nutrition & Metabolism 2021 18:67
  28. Dairy intake has been implicated in later ovarian aging but mechanism underlying the association is unknown. This study aimed to investigate (1) associations between dairy intake and metabolites previously sho...

    Authors: Nazanin Moslehi, Rezvan Marzbani, Hassan Rezadoost, Parvin Mirmiran, Fahimeh Ramezani Tehrani and Fereidoun Azizi
    Citation: Nutrition & Metabolism 2021 18:66
  29. Impaired hepatic fatty acid metabolism and persistent mitochondrial dysfunction are phenomena commonly associated with liver failure. Decreased serum levels of L-carnitine, a amino acid derivative involved in ...

    Authors: Pengtao Li, Zhengguo Xia, Weichang Kong, Qiong Wang, Ziyue Zhao, Ashley Arnold, Qinglian Xu and Jiegou Xu
    Citation: Nutrition & Metabolism 2021 18:65
  30. This study investigated the mechanisms underlying the preventive effect of dihydromyricetin (DHM) against liver fibrosis involving hepatic stellate cells (HSCs) and hepatic natural killer (NK) cells.

    Authors: Xi Zhou, Li Yu, Min Zhou, Pengfei Hou, Long Yi and Mantian Mi
    Citation: Nutrition & Metabolism 2021 18:64
  31. Previous reports regarding the predictive power of adiposity indices remain inconsistent, and longitudinal studies on this top are limited. The associations of hyperuricemia risk with changes in obesity status...

    Authors: Zonglei Zhou, Kunpeng Li, Xianzhi Li, Rongsheng Luan and Ruzhen Zhou
    Citation: Nutrition & Metabolism 2021 18:62
  32. Previous work in HEK-293 cells demonstrated the importance of amino acid-induced mTORC1 translocation to the lysosomal surface for stimulating mTORC1 kinase activity and protein synthesis. This study tested th...

    Authors: Michael S. Borack, Jared M. Dickinson, Christopher S. Fry, Paul T. Reidy, Melissa M. Markofski, Rachel R. Deer, Kristofer Jennings, Elena Volpi and Blake B. Rasmussen
    Citation: Nutrition & Metabolism 2021 18:61
  33. The practical relevance of metabolic adaptation remains a controversial issue. To the best of our knowledge, no study has properly evaluated the role of metabolic adaptation in modulating weight loss outcomes....

    Authors: Catia Martins, Jessica Roekenes, Barbara A. Gower and Gary R. Hunter
    Citation: Nutrition & Metabolism 2021 18:60
  34. To prospectively examine the associations of baseline serum uric acid (SUA) and SUA changes with incident metabolic syndrome (MetS) and update the evidence through a meta-analysis.

    Authors: Sen Chen, Nianwei Wu, Chuan Yu, Ying Xu, Chengfu Xu, Yuli Huang, Jian Zhao, Ningxiu Li and Xiong-Fei Pan
    Citation: Nutrition & Metabolism 2021 18:59
  35. Feeding rhythm disruption contributes to the development of obesity. The receptors of glucagon-like peptide-1 (GLP-1) are distributed in the wide regions of the brain. Among these regions, GLP-1 receptors (GLP...

    Authors: Yuko Maejima, Shoko Yokota, Masaru Shimizu, Shoichiro Horita, Daisuke Kobayashi, Akihiro Hazama and Kenju Shimomura
    Citation: Nutrition & Metabolism 2021 18:58
  36. Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders among women of reproductive age. This study was designed to investigate the effects of melatonin and/or magnesium supplementation ...

    Authors: Mohammad Alizadeh, Majid Karandish, Mohammad Asghari Jafarabadi, Lida Heidari, Roshan Nikbakht, Hossein Babaahmadi Rezaei and Reihaneh Mousavi
    Citation: Nutrition & Metabolism 2021 18:57
  37. High-fat diet (HFD)-induced obesity causes immune cells to infiltrate adipose tissue, leading to chronic inflammation and metabolic syndrome. Brown adipose tissue (BAT) can dissipate the energy produced by lip...

    Authors: Pengyu Fu, Rongxin Zhu, Jie Jia, Yang Hu, Chengjun Wu, Pawel Cieszczyk, Hans-Christer Holmberg and Lijing Gong
    Citation: Nutrition & Metabolism 2021 18:56
  38. The TM4 (UBAC2) protein, which contains 4 transmembrane domains and one ubiquitin binding domain, is mainly expressed in cell and nuclear membranes. The current research aimed to explore the role of TM4 in metabo...

    Authors: Lili Chen, Kuanping Ye, Xiaocheng Feng, Lianxi Li, Qin Li, Ying Huang, Xuanchun Wang, Rumei Li, Cheng Hu, Zhen Yang, Bin Lu, Yehong Yang, Jie Wen, Zhaoyun Zhang, Min He, Qinghua Wang…
    Citation: Nutrition & Metabolism 2021 18:54
  39. Soybean oil is a very common edible oil in daily life. With the changes in the dietary composition, the intake of soybean oil increased. However, the effects of dietary intake of soybean oil on testosterone pr...

    Authors: Yu Su, Zhenhua Tian, Xiangyu Qi, Dandan Luo, Luna Liu, Shuang Liu, Dongmei Zheng, Fang Wei, Zhao He and Qingbo Guan
    Citation: Nutrition & Metabolism 2021 18:53
  40. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Pariyarath Sangeetha Thondre, Helen Lightowler, Lis Ahlstrom and Andrew Gallagher
    Citation: Nutrition & Metabolism 2021 18:52

    The original article was published in Nutrition & Metabolism 2021 18:41

  41. Whether vitamin D supplementation has any effect on body fat percentage, especially among elite athletes, remains unclear. The aim of this study was to evaluate the effect of vitamin D supplementation on serum...

    Authors: Itaru Kawashima, Takashi Tsukahara, Ryosuke Kawai, Takafumi Mizuno, Shinya Ishizuka, Hideki Hiraiwa and Shiro Imagama
    Citation: Nutrition & Metabolism 2021 18:51
  42. Mitochondrial dysfunction has been implicated as a significant factor in the liver disease process. Blueberry juice and probiotics (BP) synergistically improve liver function in alcoholic fatty liver disease (...

    Authors: Houmin Fan, Yanyan Shen, Ya Ren, Qiuju Mou, Tao Lin, Lili Zhu and Tingting Ren
    Citation: Nutrition & Metabolism 2021 18:50

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